Navigation Links
Drug dosing for older heart patients should differ
Date:8/16/2013

esults led to warnings by the U.S. Food and Drug Administration and the European Medicines Agency for the use of the 10 mg/day maintenance dose of prasugrel in those populations, and consideration of a reduced dose (5 mg/day) to mitigate bleeding complications.

To examine whether older patients might benefit from a lower dosage of prasugrel, the Duke-led researchers analyzed more than 2,000 older patients who participated in a large trial called TRILOGY ACS that compared prasugrel with clopidogrel to manage acute coronary syndromes without coronary stent implantation or coronary bypass surgery.

The findings from this study, the first long-term data on outcomes specifically from elderly patients treated with the reduced dose of prasugrel, determined that a smaller dosage of 5-mg/day of prasugrel presented no greater risk of bleeding problems than the commonly prescribed 75-mg dose of clopidogrel in the elderly population.

"The findings from our study indicate how difficult it is to identify the right dose of anti-clotting medications for the elderly, to improve outcomes after a heart attack," said co-author Magnus Ohman, professor of medicine at Duke and chairman of the TRILOGY ACS study. "While a lower dose seemed intuitive, it was safe but not more effective. Future dedicated studies need to continue to find the right therapies for the vulnerable elderly patients."


'/>"/>

Contact: Sarah Avery
sarah.avery@duke.edu
919-660-1306
Duke University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Metering Pump / Chemical Injection (Metering /Dosing) Pump Market to $4.1 Billion by 2017, With a CAGR of 5.3% From 2012 to 2017 – New Report by MarketsandMarkets
2. Study of tenofovir vaginal gel shows daily dosing ineffective due to lack of adherence
3. NIH-funded analysis estimates effective PrEP dosing
4. Prisons must do more to provide health and social care to growing population of older prisoners
5. Virtual adviser helps older Latino adults get more exercise, Stanford researcher says
6. Spectrum Surgical Offers Veterinary Gold-Handled Needle Holder Repair & Refurbishing Services
7. BMA Affordable Assisted Living Community Conducts Weekly Strength Training Classes for Older Adults
8. Single dose of ADHD drug can reduce fall risk in older adults -- Ben-Gurion U researchers
9. Elevate Ventures Partners with Southwest Indiana Region Community Stakeholders to Launch Regional Entrepreneurship Action Plan
10. Research finds racial/ethnic disparities in health care among older male cancer survivors
11. Tailoring diabetes treatment to older patients yields dramatic results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... , ... July 29, 2015 , ... Today marks a ... which invests in women-led, growth companies and is led by a group of experienced ... responded positively, and voted with their dollars to be a part of the fund. ...
(Date:7/29/2015)... ... ... are privileged to announce that U.S. News & World Report has ranked the ... the nation for 2015-2016. This marks the 21st consecutive year that the USC Eye Institute ... honor to be included in the top 10 ophthalmology hospitals by U.S. News & World ...
(Date:7/29/2015)... ... July 29, 2015 , ... Fastline ... fall of 2015 on RFD-TV. , Fastline is dedicated to quality agricultural advertising, ... which contains the largest and freshest searchable agriculture equipment database in the world. ...
(Date:7/29/2015)... ... July 29, 2015 , ... Inspired by ... in March, Steven W. Meier M.D., a prominent orthopedic surgeon and regenerative medicine ... with demonstrated financial need. , “We are thrilled for this opportunity to offer ...
(Date:7/29/2015)... ... July 29, 2015 , ... It is unique for ... is a tremendous model of care. One that is very hands on and resident ... director of Monarch Landing. “She’s bringing great passion and energy, as well as a ...
Breaking Medicine News(10 mins):Health News:Sofia Fund Surpasses Investor Goals 2Health News:21 Years & Counting: The USC Eye Institute Ranks in the Top 10 Ophthalmology Hospitals in America 2Health News:21 Years & Counting: The USC Eye Institute Ranks in the Top 10 Ophthalmology Hospitals in America 3Health News:Fastline Publications to Partner with American Farmer in Upcoming Episode Airing on RFD-TV 2Health News:Orthopedic Surgeon Announces New Pro Bono Prolotherapy and Regenerative Medicine Clinic for Underserved Communities in Los Angeles 2Health News:New Medical Director Readies To Take Reins at Monarch Landing 2Health News:New Medical Director Readies To Take Reins at Monarch Landing 3
... Calif., March 11 HOYA ConBio(TM), a global,leader ... dentists who,purchase DioDent(TM) Micro 980 soft tissue lasers ... Advanced Laser,Training, a company dedicated to dental laser ... ConBio,s corporate commitment to comprehensive,laser dentistry education., ...
... EUSA,s Transatlantic ... Commercialization Platform ... Raises Over US$50 Million to Fund Acquisition and Other Investments, ... Inc (,EUSA,), a transatlantic specialty pharmaceutical company,focused on oncology, pain ...
... $0.51 Price Target, DALLAS, March 11 ... staffing company, today announced that,Wasserman Morris & Company, ... Company with a ,Speculative Buy, rating and a,price ... available at, http://www.crdentia.com/corporate/about/investor/ and through, http://www.wassermanmorris.com ., ...
... Cardiac Science,Corporation (Nasdaq: CSCX ), a ... and informatics products, announced that,Mexico,s Instituto de ... Estado (ISSSTE) ordered 282 electrocardiograph systems (ECGs) ... Science history. Instrumentation,Technologies de Mexico, Cardiac Science,s ...
... Now Available in Europe, Asia and Latin America, ... today that it has received CE Mark (Conformite Europeene),approval ... Everolimus Eluting,Coronary Stent System, offering physicians a smaller stent ... deliverability of,XIENCE V. The addition of the 2.25 mm ...
... a longtime resident of Southern,Nevada, I share our community,s ... this situation. I understand that many have questions about ... Endoscopy Center of,Southern Nevada. While I wish I were ... do so at this time on the advice of ...
Cached Medicine News:Health News:HOYA ConBio Partners With Advanced Laser Training to Offer Complementary Laser Certification Course in Dentistry 2Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 2Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 3Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 4Health News:EUSA Pharma to Acquire US Specialty Oncology Company Cytogen 5Health News:Wasserman Morris Initiates Research Coverage on Crdentia 2Health News:Cardiac Science Delivers Largest Order of Electrocardiograph Systems in Company History 2Health News:Cardiac Science Delivers Largest Order of Electrocardiograph Systems in Company History 3Health News:Cardiac Science Delivers Largest Order of Electrocardiograph Systems in Company History 4Health News:Abbott Receives CE Mark for Smaller-Size XIENCE(TM) V Drug Eluting Stent 2Health News:Abbott Receives CE Mark for Smaller-Size XIENCE(TM) V Drug Eluting Stent 3
(Date:7/29/2015)... 29, 2015  PDL BioPharma, Inc. (NASDAQ: PDLI ... revenue interest assignment agreement (the "Agreement") in which it ... ARIA ) with up to $200 million in revenue ... revenues of Iclusig ® (ponatinib).  Funding of the ... of $50 million each, with the initial amount having ...
(Date:7/29/2015)... , July 29, 2015 Touro College has announced ... CanniCare,s application for one of five media marijuana licenses to ... Dept. of Health (DOH).  If CanniCare ... medicinal cannabis.  "Our college is supportive of ... president of the Touro College System. "There is still a ...
(Date:7/29/2015)... July 29, 2015  Henry Schein, Inc. (NASDAQ: ... health care products and services to office-based dental, ... second quarter financial results. Net sales ... $2.6 billion, an increase of 0.5% compared with ... 7.5% growth in local currencies and a 7.0% ...
Breaking Medicine Technology:PDL BioPharma Completes Royalty Transaction with ARIAD Pharmaceuticals 2PDL BioPharma Completes Royalty Transaction with ARIAD Pharmaceuticals 3PDL BioPharma Completes Royalty Transaction with ARIAD Pharmaceuticals 4PDL BioPharma Completes Royalty Transaction with ARIAD Pharmaceuticals 5Touro College Announces Support for CanniCare's Medical Cannabis License Application 2Henry Schein Reports Record Second Quarter Results 2Henry Schein Reports Record Second Quarter Results 3Henry Schein Reports Record Second Quarter Results 4Henry Schein Reports Record Second Quarter Results 5Henry Schein Reports Record Second Quarter Results 6Henry Schein Reports Record Second Quarter Results 7Henry Schein Reports Record Second Quarter Results 8Henry Schein Reports Record Second Quarter Results 9Henry Schein Reports Record Second Quarter Results 10Henry Schein Reports Record Second Quarter Results 11Henry Schein Reports Record Second Quarter Results 12Henry Schein Reports Record Second Quarter Results 13Henry Schein Reports Record Second Quarter Results 14Henry Schein Reports Record Second Quarter Results 15Henry Schein Reports Record Second Quarter Results 16Henry Schein Reports Record Second Quarter Results 17Henry Schein Reports Record Second Quarter Results 18Henry Schein Reports Record Second Quarter Results 19Henry Schein Reports Record Second Quarter Results 20Henry Schein Reports Record Second Quarter Results 21Henry Schein Reports Record Second Quarter Results 22Henry Schein Reports Record Second Quarter Results 23Henry Schein Reports Record Second Quarter Results 24Henry Schein Reports Record Second Quarter Results 25
This adjustable lid speculum is angled 45 degrees and has 17 mm wire blades. It was designed to aspirate excess fluid around the eye during cataract and refractive procedures....
Angled 45 degrees. Open 13 mm blades. Screw-controlled locking mechanism. Dull finish....
Open blade design with aspiration capabilities for removing fluids from the operative site....
Solid 15 mm blades with 8 mm narrowed portion. Screw-controlled locking mechanism with stabilizing disk. Dull finish....
Medicine Products: