Navigation Links
Drug blocks 2 of world's deadliest emerging viruses
Date:3/5/2009

NEW YORK (March 5, 2009) -- Two highly lethal viruses that have emerged in recent outbreaks are susceptible to chloroquine, an established drug used to prevent and treat malaria, according to a new basic science study by researchers at Weill Cornell Medical College in the Journal of Virology. Due to the study's significance, it was published yesterday, online, in advance of the first April print issue.

The two henipaviruses that are the subject of the study -- Hendra Virus (HeV) and Nipah Virus (NiV) -- emerged during the 1990s in Australia and Southeast Asia. Harbored by fruit bats, they cause potentially fatal encephalitis and respiratory disease in humans, with a devastating 75 percent fatality rate. More recently, NiV outbreaks in Bangladesh involving human-to-human transmission have focused attention on NiV as a global health concern.

The researchers, based in Weill Cornell's pediatrics department, were surprised by their discovery that chloroquine, a safe, low-cost agent that has been used to combat malaria for more than 50 years, is a highly active inhibitor of infection by Hendra and Nipah.

"The fact that chloroquine is safe and widely used in humans means that it may bypass the usual barriers associated with drug development and move quickly into clinical trials," says Dr. Anne Moscona, professor of pediatrics and microbiology & immunology at Weill Cornell Medical College and senior author of the study. She is also vice chair for research of pediatrics at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

"Chloroquine stands a good chance of making it through the development process in time to prevent further outbreaks of these deadly infections," adds Dr. Moscona.

Like the avian flu, SARS, and Ebola viruses, Hendra and Nipah are zoonotic pathogens. That means they originate in certain animals but can jump between animal species and between animals and humans. There are currently no vaccin
'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. NLRB Blocks New Organizations Attempts to Divide UHW; SEIU UHW Committed to Securing Good Contracts With Members
2. Beta Blocker Blocks Feelings of Bad Memories
3. USC study finds that green tea blocks benefits of cancer drug
4. Jefferson researchers show antibody to breast cancer-secreted protein blocks metastasis
5. Experimental agent blocks prostate cancer in animal study
6. C5 Medical Werks Applies for Clearance, Certification and Licensing for the Global Marketing of ZirDent(TM) Ceramic CAD/CAM Dental Blocks
7. Monkey Gene That Blocks AIDS Viruses Evolved More Than Once
8. Iowa State chemists track how drug changes, blocks flu virus
9. Super-Thin Drug-Free Coating Hides Stent as It Unblocks Heart Arteries
10. Grape powder blocks genes linked to colon cancer
11. Drug Combo Blocks Pain Without Impairing Movement
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... (PRWEB) August 28, 2014 After more ... Paul Vitenas is excited to announce the opening ... its kind in any city, Mirror Mirror Beauty Boutique ... , Situated on the corner of Richmond and Drexel ... architecture, luxurious amenities, and cutting-edge technology in a private, ...
(Date:8/28/2014)... THURSDAY, Aug. 28, 2014 (HealthDay News) -- Having greater ... your ability to see distant objects in hazy conditions, ... University of Georgia researchers simulated hazy conditions in order ... levels of yellow pigment (also called macular pigment) in ... of yellow pigment, which represents accumulations of the nutrients ...
(Date:8/28/2014)... 2014 The Foundation for Women’s ... in September by alerting women to the link between ... the symptoms of endometrial cancer. , Endometrial cancer ... most common cancer. More than 52,600 will learn of ... for women with weight management challenges to know the ...
(Date:8/28/2014)... Vitals, a recognized and trusted website for ... Cosmetic Laser Dermatology one of their Top 10 Doctors ... to share their doctor experiences and rate their doctors on ... follow-ups. The Vitals Top 10 Doctor recognition means that out ... one of the highest by patients. , “I’m honored to ...
(Date:8/28/2014)... August 28, 2014 Dr. Bryan McIntosh ... downloadable ebook guide to the tummy tuck cosmetic ... surgery, the procedure itself, and how to recover well ... candid explanations. Dr. McIntosh also discusses how to have ... ensure that the procedure is as successful as possible. ...
Breaking Medicine News(10 mins):Health News:Mirror Mirror Beauty Boutique to Welcome Its First Patients 2Health News:Eye Pigment May Help Vision in Hazy Conditions 2Health News:Foundation for Women's Cancer Alerts Women to Link Between Obesity and Endometrial Cancer 2Health News:Dr. Sabrina Fabi of Cosmetic Laser Dermatology Recognized as Vitals Top 10 Doctor 2Health News:The Ultimate Guide to the Tummy Tuck Surgery eBook is Released by Dr. Bryan McIntosh 2
... U.S. HIV/AIDS Atlas , , WASHINGTON, June 22 ... Atlas ( http://www.MapHIV.org ) that highlights ... United States. The Atlas makes information on HIV/AIDS prevalence ... painting a comprehensive picture of the varying intensity of the ...
... Hoag ... of Cardiology) as its executive medical director of the Hoag Heart and Vascular Institute (HHVI). ... Newport Beach, Calif. ... Tancredi, M.D., F.A.C.C. (Fellow of the American College of Cardiology) as its executive medical director ...
... Time for Fitness! , , LOS ANGELES, June 22 ... the park or along the beach. Now a brand new product ... equipment on wheels, but with a unique design to allow your ... new concept of fitness, will be introduced to California starting from ...
... study finds, , MONDAY, June 22 (HealthDay News) -- ... blood pressure, but new research finds those extra pounds can ... especially if she experiences early menopause. , Published in the ... found that women with a body-mass index (BMI) greater than ...
... CRO expertise in $1 billion market for cancer support ... , WATERTOWN, Mass., June 22 Biomodels LLC, ... today announced that its customized research program allowed ActoGeniX ... Food and Drug Administration (FDA) approval for Phase 1b ...
... LLC, the rising star of the Sports Nutrition Industry, ... each of Vitamin Shoppe,s 400+ locations nationwide. , ... of our entire line of products," MUSCLEPHARM president Brad ... in nearly every neighborhood across the nation! Vitamin Shoppe ...
Cached Medicine News:Health News:MapHIV.org Shows California's San Francisco County Seriously Impacted by HIV 2Health News:MapHIV.org Shows California's San Francisco County Seriously Impacted by HIV 3Health News:Nationally Acclaimed Cardiologist Joins Hoag Heart and Vascular Institute as Executive Medical Director 2Health News:Pumgo Fitness Scooter Will Highlight Venice Beach This Summer 2Health News:Obesity Greatly Raises Endometrial Cancer Risk 2Health News:Obesity Greatly Raises Endometrial Cancer Risk 3Health News:Biomodels' Oral Mucositis Expertise Speeds FDA Approval for ActoGeniX's Phase 1b Trial of AGO13 in Cancer Patients 2Health News:MUSCLEPHARM Products Hit Vitamin Shoppe Shelves With a Bang! 2
(Date:8/28/2014)... , Aug. 28, 2014 MGC Diagnostics Corporation ... a conference call to discuss its financial results for ... 2014. The call will be at 4:30 p.m. ET ... financial results for the third quarter of fiscal 2014 ... Participants can dial (877) 317-6789 or ...
(Date:8/28/2014)... SAN ANTONIO , Aug. 28, 2014 ... therapeutics for the treatment of cancer, announces the recent ... the journal Steroids . The recent ... below), reviews the evolution and development of GenSpera,s prodrug technology ... activity of thapsigargin (from the plant Thapsia garganica ...
(Date:8/28/2014)... 2014 Auxilium Pharmaceuticals, Inc. (NASDAQ: ... data from trials evaluating the use of collagenase clostridium histolyticum ... adult patients with a palpable cord will be presented at ... Society for Surgery of the Hand (ASSH) being held in ... ® (CCH) is a biologic approved in the U.S., ...
Breaking Medicine Technology:MGC Diagnostics Corporation to Report Third Quarter Fiscal 2014 Financial Results on Tuesday, September 9, 2014 2GenSpera Media Advisory; "Targeting thapsigargin towards tumors" Published in Steroids 2GenSpera Media Advisory; "Targeting thapsigargin towards tumors" Published in Steroids 3Auxilium Pharmaceuticals, Inc. To Present CCH Data For Concurrent Treatment Of Multiple Dupuytren's Cords At ASSH Annual Meeting 2Auxilium Pharmaceuticals, Inc. To Present CCH Data For Concurrent Treatment Of Multiple Dupuytren's Cords At ASSH Annual Meeting 3Auxilium Pharmaceuticals, Inc. To Present CCH Data For Concurrent Treatment Of Multiple Dupuytren's Cords At ASSH Annual Meeting 4Auxilium Pharmaceuticals, Inc. To Present CCH Data For Concurrent Treatment Of Multiple Dupuytren's Cords At ASSH Annual Meeting 5Auxilium Pharmaceuticals, Inc. To Present CCH Data For Concurrent Treatment Of Multiple Dupuytren's Cords At ASSH Annual Meeting 6
... Cognizant (NASDAQ: CTSH ), a ... outsourcing services, today announced a multi-year agreement with ... services to generate clinical study reports. ... statistical programming, statistical analysis, medical writing, and document ...
... 29, 2011  Buffalo Heart Group, LLP, 2011 :  Today ... of the AngelMed Guardian cardiac monitor and alert system. The ... to get to the emergency room during an impending heart ... state of New York, and is among the very first ...
Cached Medicine Technology:Cognizant to Deliver Comprehensive Biostatistics and Medical Reporting Services for AstraZeneca 2Cognizant to Deliver Comprehensive Biostatistics and Medical Reporting Services for AstraZeneca 3Buffalo Heart Group Investigates Early Heart Attack Detection Device Developed By Angel Medical Systems 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: