Navigation Links
Drug addiction study offers new insight on compulsive behavior
Date:6/25/2012

The same neurological mechanism involved in the transition from habitual to compulsive drug use could underlie less severe, but still harmful, compulsive behaviours.

"We're trying to understand individuality in addictive behaviour. Many people can be exposed to drugs with addictive potential, for instance, but not everyone will become addicted," explains Eric Dumont, an associate professor in the Department of Biomedical and Molecular Sciences. "We believe we've identified a mechanism that makes certain people predisposed to developing addictions, and it's possible that the same mechanism underlies many - perhaps most - compulsive behaviours."

The mechanism occurs in a reward pathway of the brain. In this pathway, the brain maintains a delicate balance between pleasure and aversion, ensuring that moment-to-moment desires and dislikes remain in sync with the biological needs of the body.

Dr. Dumont and his team found unusual activity in this pathway when modeling drug addiction in rats, which exhibit a genetic predisposition to addiction comparable to humans. They believe that the pathway's balance is prone to becoming unbalanced in a certain percentage of the population. The signal to stop an activity reverses to a green light.

The team hopes that by identifying this mechanism, and possibly others like it, they will allow researchers to better understand and monitor a range of compulsive behaviours. Accordingly, Dr. Dumont's team collaborates with Dr. Cella Olmstead, associate professor of Psychology at Queen's, who recently developed an animal model of compulsive sucrose intake.

Dr. Dumont and this team were recently awarded a $520,000 operating grant from Canadian Institutes of Health Research (CIHR) to support their work for the next five years in understanding the neurological processes behind addiction behaviour.


'/>"/>

Contact: Anne Craig
anne.craig@queensu.ca
613-533-2877
Queen's University
Source:Eurekalert

Page: 1

Related medicine news :

1. Therapy exploits addiction of leukemia cells
2. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
3. New method to measure work addiction
4. Optogenetics project takes top NIDA Addiction Science Award
5. British experts update addiction treatment guidelines
6. Pornography and Masturbation Addiction Can Be Cured – Las Vegas Therapist Shares His Ideas
7. Professional Help Can Do Wonders For People Who Are Suffering From Porn And Masturbation Addiction
8. Study Suggests Vaccine May Help Kids With Brain Cancer
9. Study reveals how cancer drug causes diabetic-like state
10. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
11. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... January 16, 2017 , ... Atlanta-based incentive company Incentive ... the wheelchair accessibility industry, BraunAbility . Incentive Solutions will provide BraunAbility a ... vehicles. With this new incentive plan, BraunAbility plans to continue their tradition of ...
(Date:1/16/2017)... ... January 16, 2017 , ... Date aired: January 9, ... , Sharon Kleyne, America’s leading water educator, researcher and advocate welcomed health activist, ... The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health ...
(Date:1/16/2017)... ... January 16, 2017 , ... ... first-quality education and high-level training standards to an international multidisciplinary group of healthcare ... problems. As a way to further its mission at the grassroots level, iaedp ...
(Date:1/16/2017)... ... January 16, 2017 , ... San Francisco dentist, Dr. Ben Amini ... 3-D scanning device which is capable of taking digital impressions of teeth and gums. ... as CAD CAM restorations , in terms of speed, efficiency and patient comfort. ...
(Date:1/16/2017)... ... ... NexTec Group has been selected as a member of the Bob Scott’s VAR ... field of midmarket financial software. , Members of the VAR Stars were selected based ... on revenue and those firms chosen represent a wide range of size and many ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... , Jan. 16, 2017 CBDRx, the ... large amounts of phyto-nutrient rich hemp extract to Veteran,s ... donation of their proprietary hemp extract to Veteran,s groups ... the best hemp company in the world and through ... most nutritious, full spectrum phyto-nutrient rich hemp extract available. ...
(Date:1/13/2017)... Inc. ("InMed") (CSE: IN; OTCQB: IMLFF), today announced that ... at Eli Lilly & Company, has been appointed to InMed ... years of senior financial and executive leadership to InMed,s Board ... ... leadership position in financial and business expertise with one of ...
(Date:1/13/2017)... MURRIETA, Calif. , Jan. 13, 2017  Alfalfa, cattle, ... COPAN Diagnostic,s new environmental sampling film , which emphasizes the ... video, released today, highlights how COPAN,s ... product that simplifies the surface sampling process in the wake ... . In addition, COPAN is expanding ...
Breaking Medicine Technology: