Navigation Links
Drug-Resistant Staph Threatens Cystic Fibrosis Patients

Risk of death is 1.3 times higher for those with MRSA in respiratory tract, study shows

TUESDAY, June 15 (HealthDay News) -- Cystic fibrosis patients with methicillin-resistant staphylococcus aureus (MRSA) in their respiratory tract have worse survival rates than those without the drug-resistant bacteria, researchers have found.

The new study, published in the June 16 issue of the Journal of the American Medical Association, included 19,833 cystic fibrosis patients, aged 6 to 45, who were enrolled in the study from January 1996 to December 2006 and followed-up until December 2008. During the study period, 2,537 of the patients died and 5,759 had MRSA detected in their respiratory tract.

The death rate was 27.7 per 1,000 patient-years among those with MRSA and 18.3 deaths per 1,000 patient-years for those without MRSA. After adjusting for a number of factors, the researchers concluded that the risk of death was 1.3 times higher for patients with MRSA.

"These findings suggest that MRSA may be a potentially modifiable risk factor for death" in patients with cystic fibrosis, Dr. Elliott C. Dasenbrook, of Case Western Reserve University School of Medicine and University Hospitals Case Medical Center in Cleveland, and colleagues wrote in their report.

The new findings, along with previous data, suggest the need for more aggressive treatment of cystic fibrosis patients who are persistently MRSA-positive, Dasenbrook and colleagues pointed out, adding that the treatment should ideally be conducted in the context of clinical trials. They concluded that "the study results also reinforce the importance of following current [cystic fibrosis] infection-control guidelines to minimize transmission of MRSA," particularly in outpatient clinics with a high volume of cystic fibrosis patients.

Cystic fibrosis is a genetic, life-threatening disorder that causes severe lung damage and nutritional shortfalls. Among cystic fibrosis patients, the most common cause of death is respiratory failure secondary to lung infection. The prevalence of MRSA infection in the respiratory tract of cystic fibrosis patients has increased in recent years and is now more than 20 percent, according to background information provided in a news release from the journal's publisher.

More information

The U.S. National Heart, Lung, and Blood Institute has more about cystic fibrosis.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, June 15, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Einstein awarded NIH grant to study drug-resistant TB
2. Rapid development of drug-resistant 2009 H1N1 influenza reported in 2 cases
3. ANY LAB TEST NOW Launches New Infectious Disease Panels - Affordable Panels Test for H1N1, Staph, E. coli and Other Infectious Diseases
4. Proposed Medicaid Cuts Threatens Health Care Access for 400,000 Maryland Children
5. Fear of Frailty: Research Shows Lack of Activity Threatens Seniors' Independence
6. Women with Polycystic Ovarian Syndrome and Insulin Resistance can Lose Weight and Balance Hormones Naturally with Katie Humphrey's New E-book
7. Older patients offer insight into the future of cystic fibrosis
8. Azithromycin Doesnt Always Help Lungs in Cystic Fibrosis Patients
9. Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
10. Experimental Drug Offers Hope for Cystic Fibrosis Patients
11. Philanthropist Mark Jenney Donates to Cystic Fibrosis Foundation
Post Your Comments:
Related Image:
Drug-Resistant Staph Threatens Cystic Fibrosis Patients
(Date:11/27/2015)... ... 27, 2015 , ... Keeping in mind challenges faced by ... wellness consultation, has collaborated with a leading web-based marketplace for extra-curricular activities for ... parents and bring advice from parenting experts within their reach. As a part ...
(Date:11/27/2015)... ... November 27, 2015 , ... Avid collector, Andrew Hawley from Vintage Rock ... concert posters. This is one of Joplin's most famous and beautiful concert posters. The ... of Michigan in Ann Arbor. The According to Hawley, "It is hard to believe ...
(Date:11/26/2015)... and Cambridge, ON (PRWEB) , ... November 26, ... ... the availability of a real-time eReferral system for diagnostic imaging in the Waterloo ... X-rays, mammography, BMD and Nuclear Medicine tests directly from their electronic medical record ...
(Date:11/26/2015)... ... ... PRMA Plastic Surgery is updating their record books yet again with an ... breast reconstruction surgery! , “What an accomplishment for the PRMA team, says Dr. ... an honor to have served all of these women.” , PRMA is one of ...
(Date:11/26/2015)... ... November 26, 2015 , ... Indosoft Inc., developer and distributor ... application server to improve system efficiency and reliability. , The new Q-Suite 6 platform ... standards, the system avoids locking itself into a specific piece of software for many ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Drug Monitoring (TDM) Market: Supplier Shares, ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
(Date:11/26/2015)... 26, 2015 Research and Markets ( ... "2016 Future Horizons and Growth Strategies in ... Shares, Country Segment Forecasts, Competitive Intelligence, Emerging Opportunities" ... --> --> This new ... Italian therapeutic drug monitoring market, including emerging tests, ...
(Date:11/25/2015)... , Nov. 25, 2015 ... addition of the "Global Brain Monitoring ... offering. --> ) has ... Brain Monitoring Devices Market 2015-2019" report ... and Markets ( ) has announced ...
Breaking Medicine Technology: