Navigation Links
Drug-Resistant Staph Threatens Cystic Fibrosis Patients

Risk of death is 1.3 times higher for those with MRSA in respiratory tract, study shows

TUESDAY, June 15 (HealthDay News) -- Cystic fibrosis patients with methicillin-resistant staphylococcus aureus (MRSA) in their respiratory tract have worse survival rates than those without the drug-resistant bacteria, researchers have found.

The new study, published in the June 16 issue of the Journal of the American Medical Association, included 19,833 cystic fibrosis patients, aged 6 to 45, who were enrolled in the study from January 1996 to December 2006 and followed-up until December 2008. During the study period, 2,537 of the patients died and 5,759 had MRSA detected in their respiratory tract.

The death rate was 27.7 per 1,000 patient-years among those with MRSA and 18.3 deaths per 1,000 patient-years for those without MRSA. After adjusting for a number of factors, the researchers concluded that the risk of death was 1.3 times higher for patients with MRSA.

"These findings suggest that MRSA may be a potentially modifiable risk factor for death" in patients with cystic fibrosis, Dr. Elliott C. Dasenbrook, of Case Western Reserve University School of Medicine and University Hospitals Case Medical Center in Cleveland, and colleagues wrote in their report.

The new findings, along with previous data, suggest the need for more aggressive treatment of cystic fibrosis patients who are persistently MRSA-positive, Dasenbrook and colleagues pointed out, adding that the treatment should ideally be conducted in the context of clinical trials. They concluded that "the study results also reinforce the importance of following current [cystic fibrosis] infection-control guidelines to minimize transmission of MRSA," particularly in outpatient clinics with a high volume of cystic fibrosis patients.

Cystic fibrosis is a genetic, life-threatening disorder that causes severe lung damage and nutritional shortfalls. Among cystic fibrosis patients, the most common cause of death is respiratory failure secondary to lung infection. The prevalence of MRSA infection in the respiratory tract of cystic fibrosis patients has increased in recent years and is now more than 20 percent, according to background information provided in a news release from the journal's publisher.

More information

The U.S. National Heart, Lung, and Blood Institute has more about cystic fibrosis.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, June 15, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Einstein awarded NIH grant to study drug-resistant TB
2. Rapid development of drug-resistant 2009 H1N1 influenza reported in 2 cases
3. ANY LAB TEST NOW Launches New Infectious Disease Panels - Affordable Panels Test for H1N1, Staph, E. coli and Other Infectious Diseases
4. Proposed Medicaid Cuts Threatens Health Care Access for 400,000 Maryland Children
5. Fear of Frailty: Research Shows Lack of Activity Threatens Seniors' Independence
6. Women with Polycystic Ovarian Syndrome and Insulin Resistance can Lose Weight and Balance Hormones Naturally with Katie Humphrey's New E-book
7. Older patients offer insight into the future of cystic fibrosis
8. Azithromycin Doesnt Always Help Lungs in Cystic Fibrosis Patients
9. Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
10. Experimental Drug Offers Hope for Cystic Fibrosis Patients
11. Philanthropist Mark Jenney Donates to Cystic Fibrosis Foundation
Post Your Comments:
Related Image:
Drug-Resistant Staph Threatens Cystic Fibrosis Patients
(Date:11/30/2015)... ... 2015 , ... World Patent Marketing , a vertically ... invention that provides an economical and easy way of gaining customized curtains. , ... 2.6%," says Scott Cooper, CEO and Creative Director of World Patent Marketing. "There ...
(Date:11/29/2015)... (PRWEB) , ... November 30, 2015 , ... ... today from the new company, Sublime Beauty NATURALS®. All products are available on ... products, like essential oils, organic facial serums and USDA Certified Organic Sesame Oil ...
(Date:11/29/2015)... ... , ... The Cyber Monday deal is a deep 40% or more discount on every item ... for the skin care lover in your circle. Each Christmas, Sublime Beauty offers a ... 3 serums are staples: Collagen, Retinol and Hyaluronic Serums. , Stocking stuffers like Skin Brushes, ...
(Date:11/29/2015)... ... November 29, 2015 , ... While conventional walkers afford considerable help ... access to exercise weights. Fortunately, an inventor from Uniontown, Pa., has found a way ... enhance the benefits of a standard walker to improve the user’s quality of life. ...
(Date:11/29/2015)... IL (PRWEB) , ... November 29, 2015 , ... Effective ... In addition starting on Black Friday Target is offering a “Buy One ... This is a rare opportunity to purchase IguanaMed at a discounted price. ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 27, 2015 /PRNewswire/ ... --> Medical ... response system (PERS) market is ... 5 years with APAC being ... to see a high CAGR ...
(Date:11/26/2015)... November 26, 2015 --> ... combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced ... approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... has found that immunotherapy can be efficiently combined with ...
(Date:11/26/2015)... 26, 2015 Research and Markets ( ) ... Pacemaker Market Outlook to 2019 - Rise in Cardiac Disorders ... report to their offering. Boston ... Boston scientific and others. --> ... Biotronik, Boston scientific and others. ...
Breaking Medicine Technology: