Navigation Links
Drug Resistance Is Slowing Global Fight Against TB

Current strategies can't beat this growing challenge, researchers say

FRIDAY, Aug. 1 (HealthDay News) -- Standard methods of treating tuberculosis are failing in countries with high rates of multi-drug resistant (MDR) forms of the disease, say researchers who analyzed World Health Organization data from 2003 to 2004 for 155 countries.

In countries with high rates of MDR-TB, patients are nearly twice as likely to fail their initial treatment than patients in countries with low rates of MDR-TB -- 21.4 percent vs. 11.9 percent. The findings suggest that current TB treatment regimens need to be updated and revised, the study authors said.

"In countries where the prevalence of initial drug resistance exceeds three percent, we believe it is urgent to strengthen capacity to perform drug sensitivity testing, or to reevaluate these standard treatment regimens, given the unacceptably high rates of failure and relapse," wrote lead author Dr. Dick Menzies, director of the respiratory division at McGill University in Montreal, and colleagues.

The study was published in the first issue for August of the American Journal of Respiratory and Critical Care Medicine.

When current TB treatment regimens were developed, MDR-TB was much less common, the researchers pointed out.

In the short term, higher treatment failure and relapse rates "mean greater morbidity and mortality for patients, with greater social and economic harm for their families and communities. In the longer term, these standardized regimens may be contributing to amplification of multi-drug resistance in these countries," the researchers wrote.

"Unless those with the responsibility to boost control and research efforts increase their commitments and their financial investments by several fold, we may never see elimination of this major scourge in the decades to come," they concluded.

More information

The U.S. Centers for Disease Control and Prevention has more about TB.

-- Robert Preidt

SOURCE: American Thoracic Society, news release, Aug. 1, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Fat on chest and upper back increases risk of insulin resistance
2. Molecular fingerprint of breast-cancer drug resistance can predict response to treatment
3. Cell skeleton may hold key to overcoming drug resistance in cancer
4. Genetic approach provides new insight into trastuzumab resistance in breast cancer
5. Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
6. HIV drug resistance risk in mothers reduced by combination of common drugs
7. Overlooked Mutation Can Spur HIV Drug Resistance
8. Aspirin Resistance Boosts Heart Risks in Cardiac Patients
9. CIHR news: U of S scientists find plant gene that affects stress resistance
10. The onchocerciasis parasite showing signs of resistance
11. Unsuspected protein determines resistance to breast cancer treatment
Post Your Comments:
Related Image:
Drug Resistance Is Slowing Global Fight Against TB
(Date:11/30/2015)... ... November 30, 2015 , ... ... four states in the U.S. require dental technicians to be certified or obtain ... industry, NADL created the “What’s In Your Mouth?” campaign to inform dentists that ...
(Date:11/30/2015)... MN (PRWEB) , ... November 30, 2015 , ... ... at . The directory is specialized and only includes chiropractic clinics ... to find a competent and trustworthy alternative health practitioner when back pain sets ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... experience this summer, ushering in a new era of publicly accessible automated technology. ... shuttle, will continue to offer guests an up-close look at the shuttle at ...
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... and fun atmosphere for Halloween festivities, the Word of Life Christian Church of ... board game, and featuring a giant 1.25 ton pile of candy dubbed “Candy ...
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... community across the United States to access life-saving information provided directly ... Mesothelioma will consist of three individual conferences in three major cities: Houston, ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... 30, 2015 Nevro Corp. (NYSE: NVRO ), ... solutions for the treatment of chronic pain, today announced that ... Patent and Trademark Office (USPTO) has denied instituting an ... (the ,102 patent).  --> ... Scientific Corporation filed two petitions challenging the validity of certain ...
(Date:11/30/2015)... SAN FRANCISCO , Nov. 30, 2015 ... and Designers of Things (DoT ) co-located events ... Printing and the Internet of Things, will draw more ... San Jose Convention Center. The events, combined ... their latest technologies. --> ...
(Date:11/30/2015)... and BOCA RATON, Fla. ... for the Commercialization of Public Research (the Institute) ... with KynderMed , a medical device start-up company ... supports new company creation based on publicly-funded research, and ... Florida -based universities and research institutions. ...
Breaking Medicine Technology: