Navigation Links
Drug Resistance Is Slowing Global Fight Against TB
Date:8/1/2008

Current strategies can't beat this growing challenge, researchers say

FRIDAY, Aug. 1 (HealthDay News) -- Standard methods of treating tuberculosis are failing in countries with high rates of multi-drug resistant (MDR) forms of the disease, say researchers who analyzed World Health Organization data from 2003 to 2004 for 155 countries.

In countries with high rates of MDR-TB, patients are nearly twice as likely to fail their initial treatment than patients in countries with low rates of MDR-TB -- 21.4 percent vs. 11.9 percent. The findings suggest that current TB treatment regimens need to be updated and revised, the study authors said.

"In countries where the prevalence of initial drug resistance exceeds three percent, we believe it is urgent to strengthen capacity to perform drug sensitivity testing, or to reevaluate these standard treatment regimens, given the unacceptably high rates of failure and relapse," wrote lead author Dr. Dick Menzies, director of the respiratory division at McGill University in Montreal, and colleagues.

The study was published in the first issue for August of the American Journal of Respiratory and Critical Care Medicine.

When current TB treatment regimens were developed, MDR-TB was much less common, the researchers pointed out.

In the short term, higher treatment failure and relapse rates "mean greater morbidity and mortality for patients, with greater social and economic harm for their families and communities. In the longer term, these standardized regimens may be contributing to amplification of multi-drug resistance in these countries," the researchers wrote.

"Unless those with the responsibility to boost control and research efforts increase their commitments and their financial investments by several fold, we may never see elimination of this major scourge in the decades to come," they concluded.

More information

The U.S. Centers for Disease Control and Prevention has more about TB.



-- Robert Preidt



SOURCE: American Thoracic Society, news release, Aug. 1, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Fat on chest and upper back increases risk of insulin resistance
2. Molecular fingerprint of breast-cancer drug resistance can predict response to treatment
3. Cell skeleton may hold key to overcoming drug resistance in cancer
4. Genetic approach provides new insight into trastuzumab resistance in breast cancer
5. Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
6. HIV drug resistance risk in mothers reduced by combination of common drugs
7. Overlooked Mutation Can Spur HIV Drug Resistance
8. Aspirin Resistance Boosts Heart Risks in Cardiac Patients
9. CIHR news: U of S scientists find plant gene that affects stress resistance
10. The onchocerciasis parasite showing signs of resistance
11. Unsuspected protein determines resistance to breast cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Resistance Is Slowing Global Fight Against TB
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin ... companies that call for a minimum wage raise to $12 an hour by 2020 and ... This will restore the lost value of the minimum wage, assure the wage floor does ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
Breaking Medicine Technology: