Navigation Links
Drug Offers Promising Approach to Improve Outcome for Children with High-risk Leukemia
Date:11/15/2013

Memphis, Tenn. (PRWEB) November 15, 2013

Combining the drug gemtuzumab ozogamicin (GO) with conventional chemotherapy may improve the outcome of bone marrow transplantation for some children battling high-risk acute myeloid leukemia (AML), according to a study led by St. Jude Children’s Research Hospital. The results appear in the current edition of the journal Cancer.

For young AML patients with suitable bone marrow donors, transplantation offers the best chance of a cure. Being free of even low levels of detectable cancer cells prior to transplantation is associated with better patient survival. This analysis found that combination therapy helped to eliminate minimal residual disease (MRD) in young AML patients who initially had a poor response to chemotherapy. By reducing MRD levels prior to transplantation, it is likely that GO contributed to the excellent outcome of these patients, researchers said.

The drug, trade named Mylotarg, received accelerated approval from the U.S. Food and Drug Administration in 2000 for treatment of AML in adults. The drug was voluntarily withdrawn in 2010 following questions about its safety and efficacy. Since then several studies conducted while the drug was authorized reported promising results in adults with AML. Those reports prompted this analysis of pediatric AML patients who received GO in a clinical trial conducted while the drug was available.

Researchers said the results add to evidence that both adults and children battling AML may benefit from treatments that use a similar mechanism as GO to combat AML. The drug was not associated with severe toxicity in this or other recent studies.

Unlike traditional chemotherapy that kills rapidly dividing cells, both malignant and healthy, GO was designed to kill more selectively. The drug works by targeting a protein carried on the surface of about 90 percent of AML cells. Work has begun on new strategies, includ
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Drug offers promising approach to improve outcome for children with high-risk leukemia
2. Absolute Bird Control Offers Complete Line of Woodpecker Deterrents
3. Spectrum Surgical Offers a Range of Surgical Instrument Education Programs and Products for Ongoing Training and to Make Patients Safer
4. Medorizon Offers EMR and ICD-10 Training to Help Medical Community with Change
5. 4leafcity.com Is Launching Special Offers On Its Cardigan Sweaters For Men
6. UC Davis Children's Hospital Offers Access to Pediatric Subspecialty Care for Rural Newborns With PEANUT Program
7. Winter Issue of ChopChop Magazine Offers Edible Gift Ideas for Kids to Make for Family and Friends
8. Asbestos Found in Winnebago County Jail, Florida Asbestos Testing Company AGC Environmental Offers Tip How to Avoid the Mineral Fiber's Fatal Health Effects
9. Goji Advance Weight Loss Formula Offers and Deals: Now Customers Can Get One Extra Bottle on Select Packages
10. Venapro: The Natural Hemorrhoids Treatment Product Now Offers 50% Discount on Select Packages for Limited Time
11. Adventure To Fitness Offers Trial Weekend For Thanksgiving
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... Dallas, TX (PRWEB) May 06, 2015 ... 2, Issue 1 of Patient Experience Journal (PXJ), ... and proven practices around understanding and improving patient experience. ... elevating the patient experience conversation globally, helps align the ... and impact. , Published in association with The ...
(Date:5/6/2015)... Marketing Maven announces a ... sanitation and hygiene nonprofit by GuideStar’s Philanthropedia. , “WaterAid ... and it brings our agency great joy to work ... “The ongoing relationship between WaterAid and Marketing ... learn about and support the nonprofit as they aim ...
(Date:5/6/2015)... (PRWEB) May 06, 2015 Wolters ... healthcare professionals and students, announced today that in a ... confirmed that use of the clinical decision support resource ... the end of 2014, UpToDate users in more than ... topics per month, on average. In Germany alone, 95% ...
(Date:5/6/2015)... 06, 2015 TU-Automotive has opened press ... autonomous vehicles make it to the headlines of major ... Nissan, GM, Volvo and Hyundai ready to share their ... is the only way for press to go behind ... Wright, marketing director, TU-Automotive said “This year we’re releasing ...
(Date:5/6/2015)... GA (PRWEB) May 06, 2015 ... chosen Hexagon Geospatial technology to manage and distribute imagery, ... Australia is one of the driest continents on earth, ... through times of drought and erratic seasonal rainfalls has ... supply solutions. , Water NSW manages raw water supplies ...
Breaking Medicine News(10 mins):Health News:Patient Experience Journal Releases Spring 2015 Issue 2Health News:Marketing Maven Expands Partnership with the #1 Ranked International Water, Sanitation and Hygiene Nonprofit 2Health News:Marketing Maven Expands Partnership with the #1 Ranked International Water, Sanitation and Hygiene Nonprofit 3Health News:Current, Evidence-Based Knowledge for Physicians: UpToDate supports quick and accurate decision support for diagnosis and treatment 2Health News:Current, Evidence-Based Knowledge for Physicians: UpToDate supports quick and accurate decision support for diagnosis and treatment 3Health News:Press Registration for TU-Automotive Detroit Now Open 2Health News:Water NSW Unlocks Imagery and Elevation Data Archive Across the Enterprise using Hexagon Geospatial Solutions 2Health News:Water NSW Unlocks Imagery and Elevation Data Archive Across the Enterprise using Hexagon Geospatial Solutions 3
... Sept. 4 The American Water Works,Association (AWWA) ... y,Saneamiento de Mexico, A.C. (ANEAS) -- the National ... established that they will share expertise,and resources through ... Ruiz Morcillo and Director Roberto Olivares met,with AWWA ...
... Study finds a 37% reduction in total sleep when moms ... Nicotine in breast milk disrupts babies, sleep patterns and shortens ... , "Infants spent less time sleeping overall and woke up ... lead author Julie A. Mennella, a psychobiologist at the Monell ...
... (Nasdaq and SWX: BMRN) announced today that Emil,Kakkis, M.D., ... update at the Bear Stearns 20th Annual Healthcare Conference ... 3:00 p.m. ET. Interested parties may access a ... of the BioMarin website, http://www.BMRN.com . A,replay of ...
... Medical Inc.,(NYSE: SMA ), an independent provider ... other medical markets, announced today that it has,completed ... and Ultra Containers of America (UCA), a leading ... About Symmetry Medical Inc. Symmetry Medical Inc. ...
... Boston, MA It has been known that countries ... that results from undernutrition and overnutrition. People living in ... resources, while affluent individuals may suffer from diseases that ... the Harvard School of Public Health (HSPH) and the ...
... researchers static image of beating heart could be new screening ... to build up in the hearts of pre-diabetic people before ... new study. , Researchers at the University of Texas Southwestern ... technique that could become a new screening tool for people ...
Cached Medicine News:Health News:AWWA, National Association of Water and Sanitation of Mexico, Agree to Share Expertise and Resources for Improved Water Supply 2Health News:Nicotine in Breast Milk Shortens Baby's Naptime 2Health News:Symmetry Medical Completes Acquisition Of Specialty Surgical Instruments 2Health News:Income inequality associated with overnourishment and undernourishment in India 2Health News:Fat Builds Up in Hearts Before Diabetes Onset 2
(Date:5/6/2015)... 6, 2015 Medizone International, Inc. ... AsepticSure® Hospital Disinfection System, have recently announced that ... instrument sterilization in autoclaves, may also be used ... hospital room disinfection. Biological indicators are ... monitor the lethality of a given cleaning process ...
(Date:5/6/2015)... May 6, 2015 /PRNewswire/ -- Concord Medical Services Holdings ... ), a leading specialty hospital management solution provider ... and diagnostic imaging centers in China ... a multi-year strategic development agreement with The University ... an internationally renowned cancer research, treatment and education ...
(Date:5/6/2015)... 6, 2015 According to ... Isolation Market by Technology (Precipitation, Dialysis, Electrophoresis, Western ... (Instruments, Kits, Reagents, Resins) by Application & End ... MarketsandMarkets,  the global Protein Purification and Isolation Market ... and is expected to reach $ 6,370 Million ...
Breaking Medicine Technology:Hospital Rooms Cleaned to Autoclave Standards 2Concord Medical Services Signs Multi-year Strategic Collaboration Agreement with MD Anderson Cancer Center 2Concord Medical Services Signs Multi-year Strategic Collaboration Agreement with MD Anderson Cancer Center 3Concord Medical Services Signs Multi-year Strategic Collaboration Agreement with MD Anderson Cancer Center 4Protein Purification and Isolation Market Worth $6,370 Million by 2020 2Protein Purification and Isolation Market Worth $6,370 Million by 2020 3Protein Purification and Isolation Market Worth $6,370 Million by 2020 4
... Editor , ,Celiac disease (CD) is an ... is triggered in genetically susceptible persons by the ... and possibly oats. The condition is thought to ... and B-cell immune response, leading to mucosal inflammation, ...
... Rossi Medical Hematology and Oncology CHU Lapeyronie, Montpellier ... protein that has long been recognized as a ... a range of diagnostic markers to monitor infection ... becomes a necessity throughout the health care sector, ...
Cached Medicine Technology:Non-Invasive Diagnostic Tests for Celiac Disease 2Non-Invasive Diagnostic Tests for Celiac Disease 3Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing 2Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing 3Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: