Navigation Links
Drug Offers Hope Against Tough-to-Treat Hypertension
Date:9/13/2009

than those targeted by conventional blood pressure medications, such as calcium channel blockers and diuretics.

The study, done at 117 sites across the globe, enrolled 379 people with systolic blood pressure (the higher number in a reading) that remained at 140 or higher (130 for those with diabetes or chronic kidney disease). The recommended blood pressure reading is 120/80. All patients received 14 weeks of treatment with daily doses of 50, 100 or 300 milligrams of darusentan, or a placebo, an inactive substance.

On average, the participants' systolic blood pressure dropped 17 points with the 50-milligram dose of darusentan and 18 points with both the 100-milligram and the 300-milligram dose. A 9-point drop was recorded in the placebo group.

"That was a very meaningful reduction in blood pressure," said study lead author Dr. Michael A. Weber, professor of medicine in the cardiology division of State University of New York, Downstate College of Medicine. "Even if you subtract what happened in the placebo group, you still get about a 10-point drop, which is a clinically important finding. It translates into a meaningful reduction in the likelihood of strokes and other cardiovascular outcomes."

The major side effect was edema, excess fluid accumulation, which occurred in 27 percent of people taking the active drug and 14 percent of those taking placebo.

Because of edema, "to be really effective, darusentan probably should be used along with effective diuretic therapy," Weber said. Diuretics, which increase the flow of fluid from the body, are already widely used against high blood pressure.

If darusentan works as hoped, it will be especially useful for older people with resistant high blood pressure, Weber said. "They tend to be middle-aged or older, often with some impairment of kidney function," he said. "It is harder and harder to treat them and even more necessary to get their blood pressure treated, s
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Health care incentive model offers collaborative approach
2. Eye-staining technique offers early detection for dry eye syndrome
3. Governor Rendell Offers adultBasic Coverage to 35,000 Uninsured Pennsylvanians
4. Mylan Commences Tender Offers and Consent Solicitations for Its 5.750% Senior Notes Due 2010 and 6.375% Senior Notes Due 2015 in Connection With Its Proposed Acquisition of Mercks Generic Pharmaceutical Business
5. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
6. ADDAS Awareness Campaign Offers Resources and Education to Adults Living with AD/HD and Professionals Working With Them
7. Regence Offers InterM to Fill Gap for the Uninsured
8. National Non-Profit Organization Offers Free Mental Health Services to Military and Military Families
9. Blue Cross Blue Shield of Michigan Offers New Approach to Customer Group Wellness
10. ProAssurance Group Offers Coverage for Community Based Hospitals in Michigan
11. Super Jake Foundation Offers Hope for Pediatric Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Offers Hope Against Tough-to-Treat Hypertension
(Date:3/31/2015)... 2015 Healthpointe’s team of hip ... of their clinics. Specialties include hip dislocations, fractures, bursitis, ... athletes with hip injuries, Healthpointe has a renowned team ... the symptoms and underlying causes of the hip pain. ... prevent future damage, while taking into consideration the patient’s ...
(Date:3/31/2015)... 2015 Former 49ers linebacker Chris Borland turned ... first year of a promising NFL career. In a March ... Senior Writer Will Leitch explores the curious case of ... about the decision making process that Borland and other football ... over a large paycheck, and what impact, if any, he ...
(Date:3/31/2015)... March 31, 2015 Array Health ... technology, has announced that Lance Hood, Senior Director of ... Private Exchange Forum on April 1, 2015. The session, ... Benaissance, will address how employers can streamline and simplify ... , WHAT: “ Optimizing Employee and Employer Needs in ...
(Date:3/31/2015)... March 31, 2015 As the scientific ... Energy Balance Network (GEBN) is poised to make ... public health. GEBN is a network of scientists ... Africa, Asia and Oceania who have banded together to ... by the body (energy balance) and apply this understanding ...
(Date:3/31/2015)... York (PRWEB) March 31, 2015 Lipitor ... individuals who allegedly developed new-onset Type 2 diabetes due ... move forward in the federal multidistrict litigation now underway ... to an Order issued on March 26th, jury selection ... November 4, 2015. (In re Lipitor (Atorvastatin) Litigation, MDL ...
Breaking Medicine News(10 mins):Health News:Healthpointe Now Treating Hip Dislocations, Hip Fractures, Hip Bursitis, and Hip Strains at Locations in Southern California 2Health News:Will Leitch and the Curious Case of Chris Borland on SCI TV 2Health News:Will Leitch and the Curious Case of Chris Borland on SCI TV 3Health News:Array Health’s Senior Director of Marketing to Co-Present with Benaissance at The Institute for HealthCare Consumerism Private Exchange Forum 2Health News:Global Energy Balance Network Experts from Six Continents Join Forces to Reduce Obesity, Including the University of Colorado Anschutz Health and Wellness Center's James O. Hill, PhD 2Health News:Global Energy Balance Network Experts from Six Continents Join Forces to Reduce Obesity, Including the University of Colorado Anschutz Health and Wellness Center's James O. Hill, PhD 3Health News:Lipitor Lawsuit News: Jury Selection for First Federal Bellwether Trial to Commence November 4th 2Health News:Lipitor Lawsuit News: Jury Selection for First Federal Bellwether Trial to Commence November 4th 3
... July 31 Nevique(TM), a newly,founded skin care ... revolutionary new Omega 3 skin care technology at ... TX on August 5-8, 2008. The,Nevique(TM) skin care ... balm formulas: 1) Ultra Moisturizer, 2) Daily Conditioner, ...
... Cyberonics, Inc. (Nasdaq:,CYBX) today announced that the company will report ... its fiscal year ending April 24,2009 on Thursday, August 21, ... call to discuss those results on the same day at ... Conference Call Instructions, To listen to the conference call ...
... cells to treat fatal disease, researchers say , , THURSDAY, July ... patients with Lou Gehrig,s disease into motor neurons that are ... number of these neurons can now be created and studied ... better understanding of the disease and, one day, lead to ...
... , ... Orlando, FL (Vocus) July 31, 2008 -- ... in its "Hype Cycle for Healthcare Payers, 2008" report. Connextions, a ... retain and manage individual and small group members. , ...
... Announced, ROCHESTER, Mich., July 31 Oakland,University,s ... Robert,Folberg, M.D., as the founding dean of the ... in 2010 with a charter class of,50 students. ... of the,school -- Oakland University William Beaumont School ...
... president & chief operating officer, Medco Health Solutions, Inc.,(NYSE: ... Capital Markets 2008 Focus on,Healthcare Conference in New York ... the Millennium Broadway Hotel will begin at 9:00,a.m. ET. ... to,attend., The presentation may be heard live via ...
Cached Medicine News:Health News:Nevique Skin Care Company Introducing the Revolutionary New Omega 3 Skin Care Technology 2Health News:Cyberonics Announces Conference Call to Discuss Fiscal Year 2009 First Quarter Financial Results 2Health News:Scientists Turn Skin Cells Into Motor Neurons in ALS Patients 2Health News:Scientists Turn Skin Cells Into Motor Neurons in ALS Patients 3Health News:Connextions Cited in Leading Industry Analyst Firm's "Hype Cycle" For Health Care Provider Marketing Applications 2Health News:Connextions Cited in Leading Industry Analyst Firm's "Hype Cycle" For Health Care Provider Marketing Applications 3Health News:OU, Beaumont Name Dean of New Medical School 2Health News:OU, Beaumont Name Dean of New Medical School 3Health News:Medco to Present at the BMO Capital Markets 2008 Focus on Healthcare Conference 2
(Date:3/31/2015)... , March 31, 2015  The efficacy of continuous ... in a recently published study 1 of ultraviolet ... research team, including Curtis Donskey , M.D.  The ... for the same length of time from the same ... unit.  The results showed surprisingly low pathogen kill rates ...
(Date:3/31/2015)... According to a new ... Market (Chromatography, Electrophoresis, DNA Sequencer, PCR, Microplate Reader, Robotics, ... Centrifuge) - Global Forecast to 2019", published by ... Market is expected to reach $48.84 Billion by ... 2019. Browse   9 ...
(Date:3/31/2015)... Calif. , March 31, 2015  Frequentz Inc., ... has released a white paper to help the pharmaceutical ... 2013 Drug Supply Chain Security Act (DSCSA). The white ... stages of the GS1 EPCIS Standard(s) and ... outlook on the product tracing requirements that need to ...
Breaking Medicine Technology:VA Funded Study Validates Continuous UV-C Technology For Pathogen Reduction 2VA Funded Study Validates Continuous UV-C Technology For Pathogen Reduction 3VA Funded Study Validates Continuous UV-C Technology For Pathogen Reduction 4Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 2Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 3Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 4Life Science and Chemical Instrumentation Market Worth $48.84 Billion by 2019 5Frequentz Releases White Paper Addressing DSCSA's Current & Future Impact 2Frequentz Releases White Paper Addressing DSCSA's Current & Future Impact 3
... Causing Mitochondrial Disease More Common Than Previously,Believed, ... (UMDF) today announced landmark research finding that,one in ... could potentially cause a,mitochondrial disease in them or ... fatal disease, and mitochondrial disorders are at,the core ...
... Sanofi-aventis,(EURONEXT: SAN and NYSE: SNY) announced today ... priority review status for its New Drug,Application (NDA) ... July 31, 2008., The priority review is ... new drug product, if approved, has the potential ...
Cached Medicine Technology:New Research Shows One in 200 People Born with DNA Mutation That Can Lead to Devastating, Often Fatal Disease 2New Research Shows One in 200 People Born with DNA Mutation That Can Lead to Devastating, Often Fatal Disease 3Multaq(R) (dronedarone) Granted FDA Priority Review for Patients with Atrial Fibrillation 2Multaq(R) (dronedarone) Granted FDA Priority Review for Patients with Atrial Fibrillation 3
... designed to optimize the accuracy and precision ... products is widely recognized by customers throughout ... extended over the years and now covers ... tips including filter tips, certified pure tips, ...
... Processor is a primary component of an ... processing, sampling, and slide preparation all ... MonoPrep LBP Processor produces high-quality sample slides ... range of cytology specimen types. It processes ...
... innovative, quick and easy automated refill ... less space on your laboratory bench ... amazingly easy-to-use, one-hand system, you only ... range of Diamond Tips. All sizes ...
200 L, Racked, Pre-sterilized, 96 tips/rack, clear Recommended for 20, 25, 50, 100 and 200 L pipettes. Can also be used with 300 L pipettes when pipetting 200 L or less....
Medicine Products: