Navigation Links
Drug May Shrink Fibroids, Preserve Fertility
Date:7/1/2010

THURSDAY, July 1 (HealthDay News) -- Preliminary research suggests that a new drug treatment shrinks uterine fibroids and helps women with the non-cancerous tumors retain their fertility.

Uterine fibroids, which cause abdominal pain and heavy menstrual bleeding, are a leading cause of hysterectomy. They can also contribute to miscarriage.

"Both the fibroids and the surgical interventions commonly used to treat them can cause significant fertility problems," Dr. Alicia Armstrong, chief of gynecologic services at the U.S. National Institutes of Health's Program for Reproductive and Adult Endocrinology, said in a news release.

In two new studies, researchers tested a drug called ulipristal acetate (also known as ellaOne), which blocks ovulation and is used as a form of emergency contraception. It works by adjusting the body's reaction to the hormone progesterone.

In the studies, 57 women aged 25-50 with uterine fibroids were randomly assigned to receive treatment with the drug or a placebo. They took the pills once a day for three menstrual cycles.

The fibroids shrank in more of those women who took the drug instead of the placebo, and those who took higher doses had better results. Women who took the drug also had less bleeding than those who took the placebo.

The studies show that the drug "is an effective non-invasive treatment for fibroids that can help maintain fertility in women whose only option up to now was to have surgery," Dr. Lynnette Nieman, a principal investigator with the studies, said in the news release issued by the European Society of Human Reproduction and Embryology.

The studies are both in Phase II, the second in three phases of research required before the federal government will approve a drug for a specific use.

In an interview, Dr. Scott Chudnoff, a gynecologist and uterine fibroid specialist, said the research could lead to significant new treatments for women with fibroids. But some women might not respond the same way to the treatment, and the fibroids may return when women stop taking the drug, said Chudnoff, director of gynecology at Montefiore Medical Center in New York City.

Still, a new treatment would help doctors do a better job of personalizing their approach to individual patients, he said. The research, he added, is "definitely promising."

The study findings were to be presented Wednesday at the annual meeting of the European Society of Human Reproduction and Embryology in Rome.

More information

For more about uterine fibroids, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Scott Chudnoff, M.D., assistant professor, department of obstetrics & gynecology and women's health, Albert Einstein College of Medicine, and director of gynecology, Montefiore Medical Center, New York City; European Society of Human Reproduction and Embryology, news release, June 30, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New lung cancer drug shows dramatic results for shrinking tumors
2. Virtual visits shrink the distance in stroke rehab
3. As girth grows, risk of sudden cardiac death shrinks
4. Drug for advanced kidney cancer shrinks tumors prior to surgery
5. Cognitive Skills May Shrink With Tamoxifen
6. GYN Oncologist Uses da Vinci Surgical Robot to Preserve Fertility
7. San Jose Parks Foundation Launches "ParkForce" Campaign to Protect and Preserve San Jose's Parks & Trails
8. Woodmeister Master Builders Announces Commitment to Preserve One Foot of Forest for Each Foot it Builds
9. Transplant drug preserves kidneys, avoids toxicity
10. Smell of old books offers clues to help preserve them
11. RESOLVE: The National Infertility Association Announces Partnership with Attain Fertility
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug May Shrink Fibroids, Preserve Fertility
(Date:2/13/2016)... ... , ... Hidden Cypress in Sun City is the place to be on March 3rd to ... Weniger will be hosting this educational seminar from 5:30 p.m. – 7:00 p.m. Exciting ... pricing on offers. In addition, prizes will be given away and light refreshments will be ...
(Date:2/13/2016)... ... , ... The producers of Enterprises TV are pleased to present ... world of instantaneous consumption proves very convenient for businesses. With new technologies constantly becoming ... which pollutes our air, water, and soil. It can also threaten the lives of ...
(Date:2/13/2016)... ... February 13, 2016 , ... ... top Clinical Data Management Solution Providers list for its expertise in eClinical Solutions. ... domain expertise to serve the technology needs of global clients. DDi provides smarter ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Lymphoma Research Foundation ... research and serving the lymphoma community through a comprehensive series of education programs, ... philanthropic community at its 10th anniversary Fashion Luncheon on Monday, February 8, 2016. ...
(Date:2/12/2016)... ... ... Coco Libre, the maker of coconut water beverages with a purpose, is ... Coco Libre will offer musicians and celebrities the company’s signature Organic Coconut Water, a ... suite, held this year at the W Hollywood Hotel, has become a pre-show “must” ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Mass. , Feb. 12, 2016   HeartWare ... a conference call and webcast to discuss its financial ... 31, 2015, on Thursday, February 25, 2016 at 8:00 ... results prior to the conference call and webcast.  On ... company,s financial results, highlights from the fourth quarter and ...
(Date:2/12/2016)... 12, 2016  Memorial Hermann Health System has teamed ... to bring a one-of-a-kind experience to pediatric patients ... technologies such as 360-degree video and Google Cardboard, Howard ... literally – giving the patients and their families an ... all caught on video . Memorial ...
(Date:2/12/2016)... SEOUL, South Korea , Feb. ... Macrogen, Inc. today announced they will form a ... for precision medicine in cancer. The goal of ... digital-sorting technology with Macrogen,s high-throughput Next Generation Sequencing ... the Clinical Laboratory Improvement Amendments (CLIA) of 1988 ...
Breaking Medicine Technology: