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Drug May Help Reverse Clotting Deficiency
Date:11/28/2007

- used to fight hepatitis C -- was successfully completed by 36 percent, 53 percent and 65 percent of patients receiving 30 milligrams, 50 milligrams or 75 milligrams of eltrombopag, and only 6 percent of those in the placebo group.

"We deal with people on the [liver] transplant list with low platelet counts all the time. We've never had a drug we could give them, particularly by mouth," McHutchison said.

Two larger trials are planned which, if successful, could form the basis for FDA approval of the drug, the researchers said.

More information

There's more on ITP at the U.S. National Heart, Lung and Blood Institute .



SOURCES: John G. McHutchison, M.D., associate director, Duke Clinical Research Institute, and professor of medicine, Duke University, Durham, N.C.; Robert S. Schwartz, M.D., deputy editor, The New England Journal of Medicine, Boston; Nov. 29, 2007, New England Journal of Medicine


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