Navigation Links
Drug May Cut Tremors Associated With Parkinson's
Date:6/2/2008

But relief not on way, since FDA has said evidence of drug's effectiveness lacking

MONDAY, June 2 (HealthDay News) -- A new drug may help people with Parkinson's disease combat the tics, spasms and tremors they experience when their main medications wear off, a new study suggests.

Istradfeylline works by helping nerve and brain signals bypass the damaged dopamine system in the brain that leads to Parkinson's. A study of 395 Parkinson's patients on levodopa, a popular Parkinson's drug, found those using istradefylline experienced 24 percent less "off" time, defined as when the physical symptoms appear after levodopa wears off. A group of those studied who took a placebo showed a 10 percent decrease in "off" time.

"These results suggest that istradefylline is effective as an add-on therapy to other drugs that treat symptoms of Parkinson's disease. More importantly, this medication seems to improve 'off' time in a population in which more than 90 percent of patients are already being treated with two or more drugs," study author Dr. Mark Stacy, of Duke University Medical Center in Durham, N.C., said in a prepared statement.

The findings, published in the June 3 issue of Neurology, may not mean relief is coming soon for Parkinson's sufferers, at least in the United States. In March, the U.S. Food and Drug Administration refused to approve the drug, calling evidence of its effectiveness insufficient. The drug's manufacturer, Kyowa Pharmaceuticals Inc., has suspended development of istradefylline in North America.

The study was supported by Kyowa Pharmaceutical.

Istradefylline is a novel drug approach to Parkinson's. The disease is usually treated with medications that work on dopamine, but their effectiveness wears off after time. Istradefylline appears to connect with receptors other than dopamine to open communication with the brain.

"Istradefylline and other agents in the same cl
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. New study shows promise in reducing surgical risks associated with surgical bleeding
2. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Increased distance to physician associated with thicker skin cancer at diagnosis
5. Minorities more likely to have sleep durations associated with increased mortality
6. Income inequality associated with overnourishment and undernourishment in India
7. Maternal depression and controlling behavior associated with increased stress response in infants
8. Nurses describe dedication, frustration associated with their jobs
9. New research shows ACTOS is associated with a 38 percent lower risk of heart attack
10. New research shows ACTOS is associated with a 38 percent lower risk of heart attack
11. Produce for Better Health Foundation Releases Statement on Study Saying Fruit & Vegetable Consumption Not Strongly Associated With Colon Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Recently, WowBobble.com, the popular online supplier of funny ... to its product line. Moreover, all the company’s products ... customers can enjoy the special offer before September 29, 2014. ... prices ($12.5 for each bobblehead doll ). , ... bobbleheads. We want to make our interesting items available to ...
(Date:9/18/2014)... 18, 2014 Fit Body Boot Camp ... fitness business in the country and its popularity, as both ... to grow enormously in 2014. , The company’s annual ... taking place in Costa Mesa, CA on September 26 and ... conferences yet. Founder Bedros Keuilian, who is also considered the ...
(Date:9/18/2014)... A positive outlook on life can go far ... year, at the Weekend for Women Conference in Los Angeles, ... talk show host Mother Love will be speaking on embracing ... The always-funny Jo Anne Hart, aka Mother Love, has appeared ... widely acclaimed talk show on LATalkRadio.com, which airs weekdays from ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 How much ... That’s one of the factors contributing to the obesity ... constitutes a single serving and how to manage portion ... Control” presentation Oct. 3 at Humility House, 755 Ohltown ... Lackey will lead the informational discussion and answer questions ...
(Date:9/18/2014)... 2014 It is true that ... when building a successful brand or business online. ... has recently compared plenty of professional web hosting ... Arvixe and iPage are the best VPS hosting ... of web hosting. All-sized businesses or enterprises can ...
Breaking Medicine News(10 mins):Health News:Discounted Custom Bobbleheads Online For Sale At WowBobble.com 2Health News:With Fit Body Boot Camp World Conference Nearing, Founder Explains the Fitness Boot Camp Franchise’s Success 2Health News:With Fit Body Boot Camp World Conference Nearing, Founder Explains the Fitness Boot Camp Franchise’s Success 3Health News:DiabetesSisters Showcases Radio Talk Show Host Mother Love at Weekend for Women Conference in Los Angeles 2Health News:HMHP Workshop Addresses Portion Control 2Health News:Best Cheap Hosting USA: GreenGeeks, Arvixe And iPage Are The Best Hosting Suppliers In 2014 2
... , , LOS ANGELES, Dec. ... lives. In a decade, like so many in the preceding century ... been uncounted lives saved . Narconon is certainly ... year out, to save lives. We congratulate the selfless staffs of ...
... working on genetic puzzle to try to save the mammals ... a better understanding of an outbreak of cancerous tumors that ... new report. , Devil facial tumor disease, a kind of ... other physical contact, is one of only two types of ...
... that condition is unavoidable, expert says , THURSDAY, Dec. 31 ... stave off frailty among the elderly. , The notion is ... old that tracked the activities of over 1,000 physically active ... reasonably high-functioning. , Those who spent time volunteering were ...
... ... Online Marketing. We,ve seen a restaurant chain launched promotion that sold out in 90 minutes ... ... downturn of 2009 and closed, there were a handful that took the path less beaten ...
... , WARMINSTER, Pa., Dec. 31 ... leading home gardening company, reports brisk sales for its recently launched, ... containing different varieties for home gardeners who want to make New ... ) , The giant seedpack contains varieties of vegetables and flowers ...
... 31 The following is a statement of Matthew L. ... http://www.newscom.com/cgi-bin/prnh/20080918/CFTFKLOGO ) , North Carolina on January 2 will ... first major tobacco-growing state to implement a statewide smoke-free law ... will protect the right of North Carolinians to breathe clean ...
Cached Medicine News:Health News:Narconon Salutes Its 1,200 Staff Worldwide on 13,000 Lives Saved This Last Decade 2Health News:Narconon Salutes Its 1,200 Staff Worldwide on 13,000 Lives Saved This Last Decade 3Health News:Clues to Cancer That Could Wipe Out Tasmanian Devils 2Health News:Volunteering May Keep Elderly Stronger 2Health News:Volunteering May Keep Elderly Stronger 3Health News:Small Businesses In Singapore Outmarkets & Outperforms Bigger Players in Tough Economy With Online Marketing 2Health News:New Year's Resolution Garden Growing Sales for Burpee 2Health News:North Carolina Goes Smoke-Free on Jan. 2 in Historic Step for Health 2Health News:North Carolina Goes Smoke-Free on Jan. 2 in Historic Step for Health 3
(Date:9/18/2014)... , Sept. 18, 2014 Australian biomarker ... important US trial of its MiStat™ prostate cancer screening ... (FDA) regulatory approval upon completion. Minomic,s proprietary ... the presence of a proprietary biomarker known as the ... of prostate cancer cells. Researchers at ...
(Date:9/18/2014)... , Sept. 18, 2014 Relmada Therapeutics, ... for the treatment of chronic pain, announced today that ... to the position of  Senior Director of Clinical Development. ... Mr. James has established and led successful global clinical ... , to facilitate the clinical development of numerous ...
(Date:9/18/2014)... MILFORD, Mass. , Sept. 18, 2014 /PRNewswire/ ... developing novel therapeutics for the treatment of RNA ... National Institutes of Health (NIH) for animal testing ... multiple viral pathogens, classified as "Special Pathogens," against ... SB 9200, derived from Spring Bank,s ...
Breaking Medicine Technology:Minomic Launches US Pilot Study of MiStat(TM) Novel Prostate Cancer Screening Technology 2Relmada Therapeutics, Inc. Appoints Christopher W. James As Senior Director of Clinical Development 2Spring Bank Pharmaceuticals Announces NIH Collaboration for Testing of SB 9200 Against Multiple Viral Pathogens 2
... United States Environmental Protection Agency (EPA) announced today a ... will be screened as part of EPA,s ToxCast initiative. ... this year, involves the application of extensive and diverse ... very pleased with our contributions to ToxCast to date, ...
... Pharmaceutical Laboratories, Ltd. (NYSE Amex: CPD ) reports ... and Sun Pharma Global, Inc ("Sun Global") for a going ... more of their affiliates would acquire all of the outstanding ... Sun Global for a per share consideration of $4.75 in ...
Cached Medicine Technology:Odyssey Thera to Participate in Expanded EPA Initiative 2Caraco Receives Sun Pharma Proposal to Purchase All Outstanding Shares 2Caraco Receives Sun Pharma Proposal to Purchase All Outstanding Shares 3
The Biopro Cox comb cup is manufactured from titanium and is porous coated on the outside of the shell. The Cox comb cup accommodates a polyethylene insert....
The MPF cup is specifically designed to achieve high primary stability, a critical factor for long term success....
The Trilogy system builds on the success of the Harris/Galante Porous and HGP II cups by combining proven features with new technology designed to inhibit the formation and migration of polyethylene ...
For primary and revision cases...
Medicine Products: