Navigation Links
Drug May Be Dangerous for Kids With Graves' Disease
Date:4/17/2009

Medication known as PTU can cause liver disease, experts say

FRIDAY, April 17 (HealthDay News) -- A recommendation to restrict the use of the antithyroid drug (PTU) in children has been endorsed by the Endocrine Society.

In a letter to the editor in the April 9 New England Journal of Medicine, two experts wrote that PTU can cause severe liver disease in children and should no longer be used as a first-line treatment for children with Graves' disease, a disorder in which the thyroid gland produces more thyroid hormone than the body needs.

Liver damage has not been seen in children treated with the other thionamide derivative, methimazole, noted Dr. Scott A. Rivkees, of Yale University Medical School, and Dr. Donald R. Mattison, of the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

The Endocrine Society said this week that it supports the recommendation.

"Despite the relative rarity of Graves' disease in the young, children and adolescents account for as many as 13 of 42 cases of serious PTU-related liver failure reported to date in the medical literature and a similar disproportionate number (4 of 13) of those requiring liver transplant for this indication between 1990-2002," the society said in a news release.

An estimated 40,000 children are treated for Graves' disease each year in the United States. If 40 percent of those children are treated with PTU, then as many as one to two of those children could develop severe liver disease that could lead to a liver transplant or death.

"Even one excess death is too many if it can be prevented," the society said. It suggested that until more study was done, methimazole ought to be considered the preferred treatment for children.

More information

The U.S. National Endocrine and Metabolic Diseases Information Service has more on

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Grapefruit-Heavy Diet Helped Spur Dangerous Clot
2. Americans United for Life Condemns Ruling Increasing Minors Access to Dangerous Plan B
3. Research Finds Popular Household Pets Transmit Dangerous Parasites to Humans
4. Obesity linked to dangerous sleep apnea in truck drivers
5. Study finds cannabis use, dangerous driving behaviors interrelated
6. Supreme Court Ruling is a Victory for Consumers Injured by Dangerous Drugs, Says Hissey Kientz, LLP
7. Scientists uncover indicator that warns leukemia is progressing to more dangerous form
8. Arab-American women need supplement to boost dangerously low vitamin D levels
9. LegalView Updates Avandia Information Portal With New Articles Detailing Potentially Dangerous Side Effects
10. Cell phones dangerous for child pedestrians, UAB study finds
11. X-Tremely Dangerous Sports
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug May Be Dangerous for Kids With Graves' Disease
(Date:5/6/2015)... As the exclusive hospital of the Tampa ... Pirate Ship at Raymond James Stadium for all the “Bucs ... to be drafted into the “Bucs Babies” program last year. ... time with children, particularly those born at the Florida Hospitals ... Buccaneers fans. I really enjoyed my time participating in the ...
(Date:5/6/2015)... May 06, 2015 Edvance360 LMS-SN ... announced it won the Software & Information Industry ... in the "Best Postsecondary Learning Management Solution" category. ... has been finalists for this award seven years running, ... stands out in the industry. , "The honor ...
(Date:5/6/2015)... May 06, 2015 As Hilo ... HIMSS EMR Adoption Model, the hospital looked for ... engagement and automate processes. The leadership team realized ... to electronic workflows, patient registration still required patients ... consents. With HIMSS Stage 7 attestation fast approaching, ...
(Date:5/6/2015)... Lewisberry, PA (PRWEB) May 06, 2015 A quality ... option for a functional yet practical way to raise chickens on ... coop by Chicken Coop Condo, it will have a chicken tractor ... It will last for many years, as it is able to ... help control which areas of the land are fertilized, and it ...
(Date:5/6/2015)... Experienced Vancouver air conditioning installation and repair ... will now conduct their cooling services, including air conditioning ... commercial and residential units. Strata complex air conditioning services ... technical knowledge as well as a professionally trained staff. ... take away any old air conditioning unit to be ...
Breaking Medicine News(10 mins):Health News:Florida Hospital and the Tampa Bay Buccaneers Celebrate “Bucs Babies” Who are Turning One this Month with a Party on the Pirate Ship 2Health News:Florida Hospital and the Tampa Bay Buccaneers Celebrate “Bucs Babies” Who are Turning One this Month with a Party on the Pirate Ship 3Health News:Edvance360 Wins 2015 CODiE Award for Best LMS, Winning Twice and Maintaining Finalist Status for Seven Years Running 2Health News:Edvance360 Wins 2015 CODiE Award for Best LMS, Winning Twice and Maintaining Finalist Status for Seven Years Running 3Health News:Access Electronic Patient Signatures Help Hilo Meet HIMSS Stage 7 Paperless Targets & Save $200,000 a Year on Consent Forms 2Health News:Access Electronic Patient Signatures Help Hilo Meet HIMSS Stage 7 Paperless Targets & Save $200,000 a Year on Consent Forms 3Health News:Chicken Coop Condo Launches the Chicken Tractor 2Health News:Pro Ace Care Now Does Air Conditioning Installation for Strata Complexes 2
... supports round-the-clock monitoring , , FRIDAY, Oct. 5 (HealthDay News) ... nighttime blood pressure readings are better indicators of health ... findings support recording the ambulatory blood pressure during the ... the Oct. 6 issue of The Lancet. ...
... between, Hospitals, Coding and Patient Financial Services Departments to Positively ... ... Oct. 5 CareTech Solutions, an information,technology (IT) and health ... today that Charlie Robinson,RHIT, CCS-P, iDoc(TM) Implementation Manager, will deliver ...
... a safe and effective alternative to standard ambulance transfer ... injury or illness, finds a study published on ... 21% of visits to hospital emergency departments and previous ... manage certain conditions in the community. But current research ...
... and chronic traumatic brain injury is not strong, concludes ... such, the researchers say they cannot firmly prove nor ... brain injury. , Although the evidence for chronic traumatic ... than that in professional boxing, the safety of amateur ...
... consumers stay put in their,current Medicare prescription drug ... in their monthly premiums for 2008, says new ... CMS data and its proprietary DataFrame(R),database, Avalere experts ... Part D marketplace. Under this method, the premiums ...
... announced the,promotion of Kirk Cianciolo, D.O., MBA, CPE to ... Dr. Cianciolo is a seasoned medical,professional, with more than ... physician executive. He has been with AvMed since 2006, ... In his new position, Dr. Cianciolo will continue ...
Cached Medicine News:Health News:Daytime, Nighttime Blood Pressure Both Important 2Health News:Daytime, Nighttime Blood Pressure Both Important 3Health News:CareTech Solutions Executive to Conduct Presentation on Creating a Healthy Revenue Cycle at AHIMA Convention and Exhibit 2Health News:Paramedics can provide an effective alternative to standard ambulance service in the community 2Health News:No strong evidence linking amateur boxing with long-term brain injury 2Health News:Average Medicare Prescription Drug Premiums to Rise 21% 2Health News:AvMed Promotes Kirk Cianciolo to Senior Vice President and Chief Medical Officer 2
(Date:5/6/2015)... May 6, 2015 Alexza Pharmaceuticals, Inc. (Nasdaq: ... quarter ended March 31, 2015.  The net loss and ... $0.4 million and $13.0 million, respectively, compared to $10.7 ... 2014, respectively.  At March 31, 2015, Alexza had consolidated ... $23.9 million. "We continue to focus on ...
(Date:5/6/2015)... , May 6, 2015 /CNW/ - Celebrities, bloggers and influencers across ... media to spread the important message that melanoma prevention begins ... Maria Sharapova , Hilary Duff , and parenting ... reached out to their networks on Monday to share this ... watch The David Cornfield Melanoma Fund ...
(Date:5/6/2015)... DUBLIN , May 06, 2015 Research ... announced the addition of the "Cannulas Market ... Femoral, Injector, Infusion, Venous, Microcannula), Material (Plastic, Metal) ... Global Forecast to 2020" report to their ... expected to grow at a CAGR of 5.6% ...
Breaking Medicine Technology:Alexza Reports 2015 First Quarter Financial Results 2Alexza Reports 2015 First Quarter Financial Results 3Alexza Reports 2015 First Quarter Financial Results 4Alexza Reports 2015 First Quarter Financial Results 5Alexza Reports 2015 First Quarter Financial Results 6Alexza Reports 2015 First Quarter Financial Results 7Alexza Reports 2015 First Quarter Financial Results 8Alexza Reports 2015 First Quarter Financial Results 9Alexza Reports 2015 First Quarter Financial Results 10Celebrities Tweet Their Support of Melanoma Awareness Month and #newfamilyrule 2Global Cannulas Market 2015 - Forecasts to 2020 with Medtronic, Edward Lifesciences, Terumo, Sorin & Maquet Holding B.V. & Co. Dominating 2Global Cannulas Market 2015 - Forecasts to 2020 with Medtronic, Edward Lifesciences, Terumo, Sorin & Maquet Holding B.V. & Co. Dominating 3
... TAXUS(R) Element(TM) Stent now available in select markets ... (NYSE: BSX ) today announced the ... Coronary Stent System in select markets worldwide. ... chromium alloy engineered specifically for coronary stent applications ...
... Pa., May 18 MEDRAD Interventional(TM)/Possis(R) today announced ... the Paccocath(R) Technology closer to market as an ... the United States and Europe who suffer from ... selection of physician investigators for U.S. clinical trials ...
Cached Medicine Technology:Boston Scientific Launches Third-Generation Platinum Chromium Drug-Eluting Stent 2Boston Scientific Launches Third-Generation Platinum Chromium Drug-Eluting Stent 3Boston Scientific Launches Third-Generation Platinum Chromium Drug-Eluting Stent 4Boston Scientific Launches Third-Generation Platinum Chromium Drug-Eluting Stent 5Unique Cardiovascular Treatment Readied for Global Market: Proprietary Paccocath(R) Technology is the Only Drug Eluting Balloon with Clinical Data 2Unique Cardiovascular Treatment Readied for Global Market: Proprietary Paccocath(R) Technology is the Only Drug Eluting Balloon with Clinical Data 3Unique Cardiovascular Treatment Readied for Global Market: Proprietary Paccocath(R) Technology is the Only Drug Eluting Balloon with Clinical Data 4Unique Cardiovascular Treatment Readied for Global Market: Proprietary Paccocath(R) Technology is the Only Drug Eluting Balloon with Clinical Data 5
Anterior Stromal Puncture Cannula, 25 g. For treatment of recurrent corneal erosion. Overall length 24 mm. 5/box....
Lacrimal Cannulas, 19 g. shaft tapering to 23 g. curved cannula. Overall length 37.7 mm. 5/box....
Viscoelastic Cannula, 27 g. Angled. 7 mm angled tip cannula with unique hub that facilitates flow of viscoelastic material. Overall length 23 mm. 5/box....
Anterior Chamber Needle, 21 g., 8 mm from bend to tip. Overall length 25 mm. 5/box....
Medicine Products: