Navigation Links
Drug Improves Mobility in Some MS Patients
Date:2/27/2009

Fampridine may boost walking ability, but some risks tied to dose strength, study says

FRIDAY, Feb. 27 (HealthDay News) -- The drug fampridine improves walking ability in some people with multiple sclerosis.

In a phase III study that included 301 patients, aged 18 to 70, the participants were randomly assigned to receive either 10 milligrams of fampridine or a placebo twice a day for 14 weeks. The patients' walking speed was assessed after two weeks, six weeks, 10 weeks and 14 weeks.

The number of timed walk responders -- those who achieved a faster walking speed in at least three of the four assessments while on treatment compared to when they weren't on treatment -- was 78 out of 224 (35 percent) in the fampridine group and six out of 72 (8 percent) in the placebo group. The patients in the fampridine group also showed greater improvement in leg strength.

Eleven patients (5 percent) in the fampridine group had to withdraw from the study due to adverse events, but only two serious adverse events (focal seizure and severe anxiety) were considered to be connected with the drug, according to Andrew Goodman, of the University of Rochester Medical Center, and colleagues. But they added that the risk of seizure noted in previous studies seems to increase in a dose-dependent way with fampridine.

"Treatment with fampridine produces clinically meaningful improvement in walking ability in some people with multiple sclerosis, irrespective of disease course type or concomitant treatment with immunomodulators," the researchers concluded.

The study was published in this week's edition of The Lancet.

MS patients suffer a progressive decline in mobility, but there are few treatment options available to complement physiotherapy. While it has been suggested that fampridine may improve visual function, strength, walking ability, fatigue and endurance in MS patients, there are questions about the
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
2. Exercise and yoga improves quality of life in women with early-stage breast cancer
3. Enhanced PrecyseCode 2X(TM) Further Accelerates Remote Coding and Improves Cash Flow for Hospitals
4. Weight-based dosing of ribavirin improves outcomes for patients with hepatitis C
5. Kerry Extends, Improves Small Business Innovation Program
6. Thalidomide Improves Outcomes for Older Myeloma Patients
7. Grape Consumption Improves Antioxidant Capacity in Humans
8. JCSM: CPAP therapy improves symptoms of depression in OSA patients
9. Early intervention dramatically improves outcomes for new dialysis patients
10. New technique improves purity of medicines
11. Novel medication improves ovarian cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Improves Mobility in Some MS Patients
(Date:8/28/2014)... new study from Northwestern Medicine has found that surgical researchers ... studies -- despite a huge body of evidence showing that ... , Editors of the five major surgical journals reviewed in ... require authors to state the sex of animals and cells ... in their studies, they will be asked to justify why. ...
(Date:8/28/2014)... (Aug. 28, 2014) Solid-head power toothbrushes ... to researchers at The University of Texas Health ... The results of the study are published in ... Hygiene. Lead author and professor at the UTHealth ... notes that microbial counts were lower in the ...
(Date:8/28/2014)... about datahow to gather it, organize it, and ... analyze and share data lies at the heart ... storage, and analysis of biochemical and biological information ... used in bioinformatics have been instrumental in the ... genomics. But, in the plant sciences, bioinformatics and ...
(Date:8/28/2014)... 28, 2014 Save On Medical ... accelerator program in Tampa. Healthbox Florida has teamed ... companies grow and achieve their goals. , Healthbox ... at their launch event at the Mahaffey Theater to ... Co-founder Matt Schneider commented on the Save On Medical’s ...
(Date:8/28/2014)... Beach, CA (PRWEB) August 28, 2014 ... returns to the more than 100 million people who ... Medicine Report from the Committee on Advancing Pain Research, ... National Institutes of Health, is defined as any pain ... or even longer. And while chronic pain causes range ...
Breaking Medicine News(10 mins):Health News:Females ignored in basic medical research 2Health News:Females ignored in basic medical research 3Health News:UTHealth researchers find up to 3,000 times the bacterial growth on hollow-head toothbrushes 2Health News:Together, humans and computers can figure out the plant world 2Health News:Together, humans and computers can figure out the plant world 3Health News:Save On Medical Accepted Into Healthbox Accelerator Program 2Health News:Interventional Pain Management Expert Glenn M. Lipton, M.D. Shares Common-Sense Tips for Preventing Chronic Pain 2Health News:Interventional Pain Management Expert Glenn M. Lipton, M.D. Shares Common-Sense Tips for Preventing Chronic Pain 3
... News) -- The time between the start of substance abuse ... than for women, a U.S. government report shows. Researchers ... the first time last year and found that the average ... were primarily being treated for was 15.6 years. The ...
... -- Medical researchers are demonstrating that Office of Naval ... mines can help doctors identify and classify cancer-related cells. ... professor at Duke University and developer of the technology. ... The problem that physicians encounter in analyzing images ...
... By Denise Mann HealthDay Reporter , THURSDAY, Oct. ... likely to cause skin cancer than previously believed. New research ... suggests that the main type of ultraviolet rays used in ... of skin that is most vulnerable to the cancer-causing changes caused ...
... Thomas Jefferson University biochemistry researchers have shown for the ... hormone doesn,t activate and repress genes as once thought. In ... a heme-binding receptor to repress the same genes during the ... the last 20 years, the nuclear receptor known as EcR/Usp ...
... Oct. 6 (HealthDay News) -- As many as one-third of Medicare ... of their life, a new Harvard study finds. But ... a tricky one that can only be decided by the doctor, ... medical director at the American College of Surgeons. Nor is ...
... Where you live could play a larger role in ... study by researchers from the Johns Hopkins Bloomberg School ... low-income neighborhood in Baltimore, Maryland and found that, with ... diabetes, obesity among women and use of health services ...
Cached Medicine News:Health News:Mine-hunting software helping doctors to identify rare cells in human cancer 2Health News:Tanning Beds May Be Even Riskier Than Thought 2Health News:Tanning Beds May Be Even Riskier Than Thought 3Health News:Nuclear receptors battle it out during metamorphosis in new fruit fly model 2Health News:Many Medicare Patients Get Surgeries in Last Year of Life: Study 2Health News:Place, not race, may be a larger determinant of health disparities 2
(Date:8/28/2014)... , Aug. 28, 2014  Sequent Medical, ... enrollment in an Investigational Device Exemption ("IDE") pivotal ... the WEB™ Aneurysm Embolization System ("WEB"). Adam ... Department of Neurosurgery/Semmes-Murphey Clinic and Principal Investigator of ... the study, treating them with the WEB at ...
(Date:8/28/2014)... 28, 2014 GenSpera, Inc. (OTCQB: GNSZ), a ... cancer, announces the recent publication of the article "Targeting ... The recent article co-authored by Doan, et ... of GenSpera,s prodrug technology platform that is designed to ... plant Thapsia garganica ) directly to tumors. These ...
(Date:8/28/2014)... , Aug. 28, 2014 Synthetic ... novel anti-infective biologic and drug candidates targeting specific ... FUJIFILM Diosynth Biotechnologies UK Limited (Fujifilm), announced today ... of cGMP manufacturing of SYN-004, Synthetic Biologics, proprietary ... Clostridium difficile ( C. difficile ) infections. ...
Breaking Medicine Technology:Sequent Medical Announces Initiation Of IDE Study For The WEB Aneurysm Embolization System 2Sequent Medical Announces Initiation Of IDE Study For The WEB Aneurysm Embolization System 3GenSpera Media Advisory; "Targeting thapsigargin towards tumors" Published in Steroids 2GenSpera Media Advisory; "Targeting thapsigargin towards tumors" Published in Steroids 3Synthetic Biologics and FUJIFILM Diosynth Biotechnologies UK Announce Significant Improvement in API Manufacturing of SYN-004 for the Prevention of C. difficile 2Synthetic Biologics and FUJIFILM Diosynth Biotechnologies UK Announce Significant Improvement in API Manufacturing of SYN-004 for the Prevention of C. difficile 3Synthetic Biologics and FUJIFILM Diosynth Biotechnologies UK Announce Significant Improvement in API Manufacturing of SYN-004 for the Prevention of C. difficile 4Synthetic Biologics and FUJIFILM Diosynth Biotechnologies UK Announce Significant Improvement in API Manufacturing of SYN-004 for the Prevention of C. difficile 5
... TRACON Pharmaceuticals, a biotechnology company that develops targeted ... Phase 1 clinical results from studies of TRC105 and ... at the American Society of Clinical Oncology annual meeting ... programs target unique pathways with the potential for broad ...
... Ascenta Therapeutics announced today that eleven presentations or publications ... pan-Bcl-2 inhibitor, in several major tumor types will be ... (ASCO) Annual Meeting, May 29-June 2, in Orlando, Florida. ... .(Logo: http://www.newscom.com/cgi-bin/prnh/20090227/PH75873LOGO ...
Cached Medicine Technology:TRACON Pharmaceuticals' Small Molecule TRC102 and Antibody TRC105 to be Presented at ASCO 2009 2Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting 2Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting 3
... The Isoseeds I-125 are brachytherapy sources which ... of localized tumors, especially in the prostate. ... the conclusion of the therapeutic effect, i.e. ... are intended for single use. They are ...
... Four 64 mirrors for complete ... lens rotation. Directly hand held for ... or small holding ring. Small diameter ... gonioscopy without methylcellulose. Advanced technology, multi-layer ...
... Three mirrors of 64, ... small diameter contact surface for ... can be viewed through the ... Multi-layer polymer coating protects mirrors ...
West lacrimal cannula blunt tip with side port....
Medicine Products: