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Drug Improved Survival in Mice With Cystic Fibrosis
Date:2/19/2010

can increase bicarbonate production in intestinal tissue by increasing the activity of bicarbonate-producing enzymes called carbonic anhydrases.

"For the first time, we are able to use a drug that activates bicarbonate transport without affecting chloride transport, and see improvement in the disease," Harmon said.

The findings, published in the Feb. 14 issue of Nature Medicine, may lead to new treatments for cystic fibrosis.

More information

The Cystic Fibrosis Foundation answers questions about cystic fibrosis.



-- Robert Preidt



SOURCE: University of California, San Diego Health Sciences, news release, Feb. 14, 2010


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