Navigation Links
Drug Helps Asians Battling Liver Cancer
Date:12/17/2008

Sorafenib boosts survival, even when tumor is linked to hepatitis B, researchers say

TUESDAY, Dec. 16 (HealthDay News) -- The drug sorafenib increased overall survival in Asian-Pacific patients with advanced liver cancer, according to the results of a study that included 226 patients in China, South Korea and Taiwan.

The 150 patients in the treatment group received 400 milligrams of sorafenib (Nexavar) twice a day in six-week cycles, while those in the control group received a placebo.

Median overall survival was 6.5 months for those in the treatment group and 4.2 months for those in the control group. The study also found that sorafenib prolonged the time to progression and disease control rate.

Side effects among those taking the drug included skin reactions on the hands and feet, diarrhea and fatigue. The findings appear online and in the January print issue of The Lancet Oncology.

Sorefenib has been approved in Europe and the United States for treatment of advanced liver cancer, but approval in China was dependent on results from a study in Asian-Pacific patients, who account for 75 percent of liver cancer cases worldwide, according to background information in the study. Liver cancer is associated with chronic infection with hepatitis B (HBV), which is common in the Asian-Pacific region. Many patients are diagnosed when they have advanced liver cancer, which means that surgery is an option for only 20 percent of patients.

"Although other studies suggest that sorafenib might be less efficacious in patients with HBV, we do not agree with these conclusions, and believe that the large proportion of patients with HBV enrolled in our study supports the efficacy of sorafenib in this important patient population," wrote Dr. Ann-Lii Cheng, of the National Taiwan University Hospital, and colleagues.

More information

The American Liver Foundation has more about liver cancer.



-- Robert Preidt



SOURCE: The Lancet Oncology, news release, Dec. 16, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Give Your Heart a Holiday: Eating Almonds Helps Support Healthy Fat Levels
2. Rotary Action Group Helps Launch Major Public-Private HIV Prevention Initiative in Kenya
3. Music Therapy Helps Relieve Anxiety, Emotions of Cancer Diagnosis
4. Combo Therapy Helps Multiple Myeloma Patients
5. Ultrasound Screening Helps Prevent Stroke in Children With Sickle Cell Disease
6. BCBSNC Helps Customers Fight Recession With Free Generics
7. Integrated Benefits Institute Helps Employers Make the Business Case for Health and Productivity Improvement
8. Dismissed leukemia drug helps cll patients, studies show
9. Belmont(R) Rapid Infuser Helps Save Officers Life
10. Treating sleep apnea in Alzheimers patients helps cognition
11. WHO tool helps target bone treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Helps Asians Battling Liver Cancer
(Date:4/29/2016)... ... April 29, 2016 , ... Jvion, the market ... funding led by Eastside Partners, with participation from existing investor Martin Ventures. ... and accelerate its technology and product roadmap. , “Jvion is experiencing ...
(Date:4/29/2016)... ... April 29, 2016 , ... CURE Media Group , ... with cancer, today announced that Lynne Malestic, RN, of Eisenhower Lucy Curci Cancer ... Healer® for Oncology Nursing , which honors nurses who have dedicated their careers ...
(Date:4/29/2016)... ... 29, 2016 , ... Natren, Inc. recently sent representatives to ... Petbiotics ™, as they fondly call them. As animal lovers, they were deeply ... non-profit organizations. Animal rescues across the nation face huge hurdles rescuing animals in ...
(Date:4/29/2016)... ... April 29, 2016 , ... Coalition Duchenne, ... dystrophy, and funding for Duchenne research, participated in the April 25 U.S. Food ... novel Duchenne drug eteplirsen. The meeting at the Marriott Conference Center in Hyattsville, ...
(Date:4/29/2016)... , ... April 29, 2016 , ... ... data for 2014. Each year, reproductive endocrinologists are required to report in ... main organization of professionals dedicated to the practice of assisted reproductive technologies in ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 2016 Transparency Market Research has ... - Global Industry Analysis, Size, Share, Growth, Trends, and ... global skincare devices market was valued at US$ 7,255.8 ... a CAGR of 10.1% from 2015 to 2023 to ... the full Skincare Devices Market (Treatment Device - LED Therapy ...
(Date:4/27/2016)... , April 27, 2016 ... addition of the  "Global Anesthesia Disposables Market ... http://photos.prnewswire.com/prnh/20160330/349511LOGO ) ,The global anesthesia ... a CAGR of 4.03% during the period ... a major threat to patients, safety. Organizations ...
(Date:4/26/2016)... Diplomat Pharmacy, Inc. (NYSE: DPLO) is pleased ... Pharm D., to Vice President of Education and Quality. ... will continue to lead and oversee Diplomat University, an ... and training to Diplomat employees and external professionals on ... also houses the quality assurance department, which focuses on ...
Breaking Medicine Technology: