Navigation Links
Drug Given 24 Hours After Stroke Helps Repair Brain Tissue
Date:9/3/2008

Bryostatin may also work in patients with Alzheimer's and traumatic injury, study says

WEDNESDAY, Sept. 3 (HealthDay News) -- A little-used cancer drug called bryostatin can repair brain tissue if it's administered within 24 hours after a stroke, according to U.S. researchers.

Current stroke treatments must be administered within three hours and aren't able to repair damaged brain tissue, the scientists said.

"Today's stroke patient has precious minutes to receive care without suffering irreversible damage or death. One of the greatest challenges in modern medical practice is finding an effective treatment that extends that treatment time and repairs damage. Bryostatin could be an answer," Dr. Daniel Alkon, scientific director at the Blanchette Rockefeller Neurosciences Institute, said in an institute news release.

In an article in the Sept. 3 issue of the Proceedings of the National Academy of Sciences, Alkon and colleague Professor Miao-Kun Sun describe how bryostatin -- which is being investigated as a treatment for Alzheimer's disease -- repairs the brain and improves memory.

More than 780,000 strokes occur each year in the United States. Stroke is the third leading cause of death in the United States and the leading cause of long-term disability in the developing world. Almost 75 percent of all strokes occur in people older than 65, and the risk of suffering a stroke more than doubles each decade after age 55, according to background information in the news release.

"We're facing an aging Baby Boomer population, an influx of 55-plus Americans, and treatment that is less time-restrictive and able to repair the brain if a stroke destroys tissue is urgently needed," Alkon said.

In animal tests, bryostatin rescued dying neurons, stimulated the growth of new neuron connections, and restored memory. The drug is effective when administered up to 24 hours after a stroke, according to the researchers.

The drug may also prove effective in preventing and/or reversing brain degeneration in patients with Alzheimer's disease and traumatic brain injury, Alkon said.

The researchers are in discussion with the U.S. Food and Drug Administration to begin clinical trials of the drug.

More information

The U.S. Food and Drug Administration has more about stroke prevention and treatment.



-- Robert Preidt



SOURCE: Blanchette Rockefeller Neurosciences Institute, news release, Sept. 3, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. More sick leave given to men by male GPs compared with female counterparts
2. 10 Million Children Must Be Given a Chance
3. Promising new TB drug given special status by US and European regulators
4. Over 300 Children Are Given New Smiles
5. Bariatric Surgery Center of Excellence Designation Given to Montefiore by the American College of Surgeons
6. Pelosi: By Literally Fixing Broken Hearts, Dr. DeBakey Has Given Hope and Health to Millions
7. PartsSource Given 2008 Leading Edge Award for Second Straight Year
8. Less Intensive Treatment Given Diabetic Women With Heart Disease
9. PartsSource Given 2008 World Class Customer Service Award for Second Straight Year
10. Nursing Loan Forgiveness Programs -- More Applicants Needed by June 30, 2008
11. Limiting Residents Hours Has Little Impact on Patient Mortality
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... May 26, 2016 , ... MadgeTech will be showcasing its line ... in Warner, New Hampshire at the MadgeTech headquarters. With products sold in more than ... by government agencies, including NASA. , In 2012, NASA strategically set up 17 ...
(Date:5/26/2016)... ... May 26, 2016 , ... Memorial Day Weekend marks ... Amica Insurance is sharing tips to make sure your family and vehicle are ... National Safety Council, there may be 439 deaths and an additional 50,500 serious injuries ...
(Date:5/26/2016)... ... May 26, 2016 , ... Nike Yoga Camps at ... daily practices, arts & crafts, discussions, and games all geared towards enhancing your ... have combined backgrounds in kids’ yoga, collegiate sport yoga instruction, and global yoga ...
(Date:5/26/2016)... ... May 26, 2016 , ... Bunion Bootie , the manufacturer ... treatment was more than humbled by customer demand over the Mother’s Day Weekend promotion. ... sale. Now that Bunion Bootie has completely replenished its inventory levels, it hopes to ...
(Date:5/26/2016)... ... May 26, 2016 , ... Workrite ... sales leadership and to further develop their rapidly expanding portfolio of customer and ... with a concentration in Marketing and an M.B.A. with concentration in management from ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... 2016 A key trend that ... emergence of new treatments. Cardax, a development stage life ... The therapy is expected to fulfil large unmet medical ... conducting studies to develop new treatments for osteoarthritis. One ... involved in osteoarthritis are being investigated, and early trials ...
(Date:5/26/2016)... Since its commercial introduction in ... life science tool for conducting genetic studies in a ... in its new report that the industry sits on ... by a range of new applications in the clinical ... http://photos.prnewswire.com/prnh/20140723/694805 ) , Since the Human ...
(Date:5/25/2016)... HILDEN , Deutschland und GERMANTOWN, ... Zusammenarbeit mit Therawis bedient ... Entscheidungen bei Brustkrebs   QIAGEN N.V. ... QIA) gab heute bekannt, eine Lizenz- und Entwicklungsvereinbarung ... prädiktiver Assays für die Onkologie eingegangen zu sein. ...
Breaking Medicine Technology: