Navigation Links
Drug Effective for Temporary Sleep Disruptions
Date:12/2/2008

Trials of tasimelteon show it could aid shift workers, people affected by jet leg

TUESDAY, Dec. 2 (HealthDay News) -- The experimental drug tasimelteon helps treat temporary insomnia caused by jet lag or night shifts, according to the results of two new clinical trials.

The phase II study included 39 people randomly assigned to receive either 10 milligrams, 20 mg, 50 mg or 100 mg of tasimelteon, or a placebo. They were monitored for seven nights -- three at baseline, three after a five-hour advance of sleep-wake schedule with treatment before sleep, and one night after treatment.

The phase III trial included 411 people who had transient insomnia induced in a sleep clinic by a five-hour advance of their sleep-wake cycle. They received either 20 mg, 50 mg, or 100 mg of tasimelteon, or a placebo, 30 minutes before bedtime.

The patients in the trials were monitored to determine their sleep efficiency (amount of actual sleep during their time in bed) and sleep latency (time it took them to fall asleep). Compared to placebo, tasimelteon (a melatonin analogue) improved sleep efficiency and reduced sleep latency, according to the researchers. They also found that patients taking tasimelteon showed an earlier shift in plasma melatonin rhythm.

The findings were published online and in an upcoming print issue of the The Lancet.

"The development of melatonin analogues, which specifically target melatonin receptors, will also help us to understand more about the role of the hormone melatonin in the regulation of sleep," the American and Australian researchers said in a journal news release.

"By simultaneously improving sleep latency and sleep maintenance with a shift in circadian rhythms, tasimelteon has the potential for the treatment of patients with transient insomnia associated with circadian rhythm sleep disorders, including people affected by jet leg, or those who work at night, and ea
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. New treatment effective in counteracting cocaine-induced symptoms
2. Use of certain lipid measures not more effective in predicting coronary heart disease
3. HPV vaccine does not appear to be effective for treating pre-existing HPV infection
4. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
5. Stanford study highlights cost-effective method of lowering heart disease risks
6. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
7. Case Management Cost-Effective Way to Cut Heart Risks
8. ResMed Names Kieran Gallahue as Chief Executive Officer, Effective January 1, 2008.
9. Nasal Anthrax Vaccine Proves Effective in Animal Study
10. Family-based treatment more effective than supportive psychotherapy in treating bulimia
11. Consumer Reports Analysis: Drugs for Nerve Pain, Fibromyalgia Effective, But Not Always Best
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Effective  for Temporary Sleep Disruptions
(Date:12/20/2014)... Francisco, CA (PRWEB) December 20, 2014 ... Social Innovation company just launched first birthday focused portal ... services, “MERRY BIRTHDAY MESSAGE” launched in both US and ... MERRY BIRTHDAY MESSAGE : http://merrybirthday.net/message/ , MERRY ... for everyone’s birthday around the world. , Features, Choose ...
(Date:12/20/2014)... Xarelto bleeding lawsuits filed by men ... and other serious side effects will be consolidated in ... coordinated pretrial proceedings, Wright & Schulte LLC reports. The ... order Friday to transfer 21 Xarelto lawsuits and over ... to the Louisiana district court for coordination by Judge ...
(Date:12/19/2014)... Today, Balfleet.com , a leading ... its formal dress promotion. All the old and new ... off. , Balfleet.com is well-known for its high quality ... dresses, cocktail dresses and more. Its formal dresses are ... and they can create an elegant look when paired ...
(Date:12/19/2014)... Tampa, FL (PRWEB) December 19, 2014 ... Celliant Revitalizing Bedsheets are now available. Celliant, the ... in both sheets and pillowcases. , There are ... clinically proven additional circulation, increased oxygenation and balanced ... quality, faster healing and pain relief; enhanced athletic ...
(Date:12/19/2014)... Canadian, OK (PRWEB) December 19, 2014 ... is home to Lake Eufaula, the state’s largest lake ... lovely lakeside town is home to a little more ... at 1:00 P.M. on Saturday, the 6th of December. ... made its way through downtown Eufaula on Main Street. ...
Breaking Medicine News(10 mins):Health News:Atore, Inc. Releasing the First Birthday Portal 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Balfleet.com Announces Its Formal Dress Promotion For 2015 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3
... on June 11th, during Games for Health Conference in Boston, MA ... you take care of your brain when every week brings a ... other? Do supplements improve memory? Do you need both physical and ... training approach, if any, is worth your time and money? ...
... New York Hospital Queens One of Clinical Sites, Research Director is ... the world,s most respected medical journals, the New England Journal ... explores treatments for people with both Type 2 diabetes and coronary ... Hospital Queens was one of the sites that conducted this study. ...
... Carl D. Stevens, MD, MPH, a researcher at Los ... BioMed), recently received the Award for Excellence in Education ... at the University of California, Los Angeles (UCLA) established ... excellence in education." Dr. Stevens is a ...
... places where young women outnumber young men, research shows the ... men feel less pressure to settle down as more women ... reach their 30s, the reverse is true and proportionately more ... Daniel Kruger, a University of Michigan researcher who ...
... may meet criteria for full alert, agency says , TUESDAY, ... H1N1 swine flu in Australia may tip the balance and ... flu pandemic since 1968, agency officials said Tuesday. , Cases ... most occurring in the southern state of Victoria. Rapid spread ...
... be key to a restful night, study finds , TUESDAY, ... and having trouble getting a good night,s sleep, you may ... insomnia reported that they slept better after trying meditation, according ... SLEEP, the annual meeting of the Associated Professional Sleep Societies, ...
Cached Medicine News:Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 2Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 3Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 4Health News:First Brain Training Consumer's Guide Debunks Ten Brain Health Myths and Reviews 21 Products 5Health News:Landmark Study Published in New England Journal of Medicine 2Health News:Landmark Study Published in New England Journal of Medicine 3Health News:When young men are scarce, they're more likely to play the field than to propose 2Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 2Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 3Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 4Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 5Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 6Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 7Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 8Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 9Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 10Health News:WHO Declaration of Swine Flu Pandemic Looks Imminent 11Health News:Meditation May Help Put Primary Insomnia to Bed 2
(Date:12/19/2014)... SAN DIEGO , Dec. 18, 2014  RESMED INC. ... report its second quarter of fiscal year 2015 results on ... market close. A press release with ResMed,s results will be ... will host a webcast to discuss operating results and future ... at 1:30 p.m. US Pacific Time and the live webcast ...
(Date:12/19/2014)... , Dec. 19, 2014  Eli Lilly and ... Paris: FR0011184241 – ADOC) today announced a worldwide licensing ... BioChaperone Lispro, for treatment in people with type 1 ... proprietary BioChaperone® technology and is currently in Phase Ib ... Lispro with the goal of optimizing glucose levels during ...
(Date:12/17/2014)... Revenue and earnings above the previous year - ... In the past 2013/14 fiscal year (ended 30 September ... 4.287 billion (last year: EUR 4.190 billion) despite unfavorable currency ... million. "Overall, 2013/14 was a successful fiscal year for the ... CEO of Carl Zeiss AG. "Thanks to our broad portfolio ...
Breaking Medicine Technology:ResMed To Announce Second Quarter 2015 Results 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3ZEISS Asserts its Position in Difficult Environment 2
... Holdings, Inc. ("Bacterin") (OTC Bulletin Board: BIHI ... announced that it launched its OsteoSponge®SC product at the ... taking place February 15-19 in San Diego, CA.  Based ... the Food and Drug Administration to market OsteoSponge®SC as ...
... Feb. 16, 2011 MedAptus®, the market leader ... England Baptist Hospital (NEBH) has selected the company,s ... medicine providers. The NEBH hospitalist team, comprised of ... Inpatient Edition via the web as well as ...
Cached Medicine Technology:Bacterin International to Announce Launch of OsteoSponge®SC at American Academy of Orthopedic Surgeons 2011 Annual Meeting February 15-19 2Bacterin International to Announce Launch of OsteoSponge®SC at American Academy of Orthopedic Surgeons 2011 Annual Meeting February 15-19 3Hospitalists at New England Baptist Hospital Choose MedAptus 2
... of flexible lighting products. The first is ... different sizes 5", 10", and 15" (refers ... light). These lights are for use in ... ,The second group of flexible lights is ...
Designed to be used for neuromuscular blockage monitoring. Provides for easy placement over the ulnar nerve on a patient's wrist. Dual element permits non-invasive monitoring using a single electrode...
... standby switch maintains power to the instrument without ... pulse/s) , Tetanus: 100 Hz (200 pulses/s) ... Current: Adjustable from 0-70 mA , Stimulus ... Indicators: Battery LED (green) indicates that the units ...
... peripheral nerve stimulator from B. Braun Medical. ... nerve stimulator functionality for over 10 years. ... available, a unique, under-the-glove hand held remote ... Dig. It allows the anesthesia provider operating ...
Medicine Products: