Navigation Links
Drug Duo May Help Fight Aggressive Form of Breast Cancer
Date:1/17/2012

ow them and see how the approaches affected survival.

Baselga stressed that the study looked only at women with early-stage HER2-positive breast cancers, and that the drug Tykerb is approved now only for advanced breast cancers.

The study is well done and important, said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society. The two drugs, he said, "affect the same pathway but do it in a different way."

While the combination showed a better response rate, "there is also an increased level of side effects," he noted.

While no major heart problems occurred, those on Tykerb alone or the two-drug combination had more diarrhea. Liver-enzyme alterations were also more frequent when Tykerb was used.

GlaxoSmithKline notes that liver toxicity with the drug may be severe and that deaths have been reported, although the cause of the deaths has not been determined.

The important question, however, has not been answered yet, Lichtenfeld said. That's the effect on overall survival in using the two-drug approach. The researchers are continuing to evaluate that.

In another study, published online Jan. 17 in The Lancet Oncology, researchers from Germany reported that Tykerb is less beneficial than Herceptin as a single-drug therapy.

They assigned 620 women with HER2-positive breast cancer to get standard chemotherapy plus Herceptin or Tykerb.

They looked to see which drug was better at eliminating invasive cancer in the breast and metastatic cells in the lymph nodes. While 30 percent of those in the Herceptin group had this response, 23 percent of the Tykerb group did. The study was funded by drug makers GlaxoSmithKline, Roche and Sanofi-Aventis.

Baselga reports receiving honoraria from Roche; other co-authors report receiving speaking fees or honoraria from GlaxoSmithKline and fees from other drug companies.

More information

To learn more about breast cancer, includ
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. MARA Fights Malaria With WaveMaker and Amazon Web Services
2. NASBE Supports First Lady Michelle Obama in Fight Against Childhood Obesity
3. Planting Seeds to Fight Childhood Obesity
4. AMA Joins First Lady in Fight Against Childhood Obesity
5. A common cholesterol drug fights cataracts, too
6. In Support of the Lets Move Campaign to Fight Childhood Obesity, Verizon Thinkfinity Providing Free Educational Resources on Nutrition and Exercise
7. The Alliance for a Healthier Generation Names Celtics Captain Paul Pierce National Athlete Spokesperson in the Fight Against Childhood Obesity
8. Tiny fruit fly could offer big clues in fight against obesity, researcher says
9. Family's Fight to Save Child Spreads Hope Around Globe
10. Businesses Rally Big Efforts to Benefit the Susan G. Komen Phoenix Affiliates Fight Against Breast Cancer
11. 29 Clear Channel stations Nationwide Raise Nearly $2.8 Million to Help Save the Lives of Kids Fighting Cancer and Other Deadly Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Duo May Help Fight Aggressive Form of Breast Cancer 
(Date:8/28/2014)... 28, 2014 Bleeding gums are not to ... flossing, according to the prosthodontists at the Anacapa Dental Art ... serious medical conditions, Dr. Saj Jivraj and Dr. Mamaly Reshad ... are not properly cleaning your teeth all the way down ... bleed easily,” Dr. Jivraj said. , Despite their reputations for ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 In the ... and private practices struggle with: How can the overall ... new multi-year study of the healthcare industry tackles this ... correlation between employee job satisfaction and the quality of ... can be found in “ Organizational Factors related to ...
(Date:8/28/2014)... AMTC graduate, rising star and The Voice Season ... the Top 10 finalists for Pepsi’s Southern Original . He’s ... for his mentor and coach from The Voice and country music ... slot on Thursday, August 28th at 9:00 pm at Tootsie’s at ... will perform at the Gulf Coast Jam main stage on Sunday, ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Top ... many web hosting companies and announces Bluehost, HostMonster ... recommended suppliers for the webmasters worldwide who want ... rates. , As the world’s most popular server-side ... and many other general-purpose programs. It is now ...
(Date:8/28/2014)... August 28, 2014 Alpine, NJ resident ... of his team, Zebras In Tiaras, to benefit the ... be held October 26, 2014 in Foley Square, New ... immunodeficiency community. Primary immunodeficiency diseases (PI) are a group ... which part of the body’s immune system is missing ...
Breaking Medicine News(10 mins):Health News:Elite Oxnard, Calif., Dentists Offer 4 Tips for Protecting Children’s Gums 2Health News:Elite Oxnard, Calif., Dentists Offer 4 Tips for Protecting Children’s Gums 3Health News:Elite Oxnard, Calif., Dentists Offer 4 Tips for Protecting Children’s Gums 4Health News:Elite Oxnard, Calif., Dentists Offer 4 Tips for Protecting Children’s Gums 5Health News:New Healthcare Study Explores Strategies for Improving Patient Care 2Health News:New Healthcare Study Explores Strategies for Improving Patient Care 3Health News:New Healthcare Study Explores Strategies for Improving Patient Care 4Health News:Rising Star Brandon Chase Named Finalist in Pepsi Southern Original Contest 2
... officials say company distributed ,adulterated, peanut butter products in ... -- The Georgia facility that produced the peanut butter ... in the past distributed questionable peanut butter product, U.S. ... 2008, Peanut Corporation of America, which owns the now-closed ...
... for Patient-Provider Decision MakingFurther Action Needed to Ensure ... Senate today improved on a comparative effectiveness research ... $1.1 billion dollar research effort on clinical effectiveness," ... of the National Alliance for Hispanic Health, the ...
... Ringling Bros.(R) Conservation and Breeding ProgramVIENNA, Va., Jan. 27 ... Elephant Conservation (R) proudly announces the ... twenty-second birth in what has proven to be the most ... importantly, this is the first calf in the Ringling ...
... Healthcare Realty,Trust Incorporated (NYSE: HR ) ... the market closes, it will report results for the ... February 24, 2009, at 9:00 a.m. Central Time, Healthcare ... results, quarterly activities,general operations of the Company and industry ...
... has completed a new study on uric acid and C8 and ... increased uric acid is associated with higher levels of C8 and ... can cause an increase in uric acid.The Science Panel team recently ... (also known as PFOA) and C8S (also known as PFOS) in ...
... St. Jude Children,s Research Hospital and the Children,s Oncology ... leukemia (ALL) scores of inherited genetic variations that clinicians ... more effective chemotherapy for this cancer. ... rates for ALL exceed 80 percent, patient responses vary ...
Cached Medicine News:Health News:Salmonella Outbreak Plant Shipped Dubious Product Before: U.S. Health Officials 2Health News:Salmonella Outbreak Plant Shipped Dubious Product Before: U.S. Health Officials 3Health News:Statement on Comparative Effectiveness Research Under Senate Appropriations Committee Stimulus Bill 2Health News:Ringling Bros. and Barnum & Bailey(R) Proudly Announces Its First Elephant Calf Born From Artificial Insemination 2Health News:Ringling Bros. and Barnum & Bailey(R) Proudly Announces Its First Elephant Calf Born From Artificial Insemination 3Health News:Ringling Bros. and Barnum & Bailey(R) Proudly Announces Its First Elephant Calf Born From Artificial Insemination 4Health News:Ringling Bros. and Barnum & Bailey(R) Proudly Announces Its First Elephant Calf Born From Artificial Insemination 5Health News:Healthcare Realty Trust Announces Fourth Quarter Earnings Release Date and Conference Call 2Health News:C8 Science Panel Completes Uric Acid Study 2Health News:St. Jude finds more than 100 gene variations linked with response to leukemia treatment 2Health News:St. Jude finds more than 100 gene variations linked with response to leukemia treatment 3
(Date:8/27/2014)... , Aug. 27, 2014 Sihuan Pharmaceutical ... the "Company"), a leading pharmaceutical company with the ... China,s prescription drug market, today ... and its subsidiaries (collectively the "Group") for the ... Financial HighlightsFor the Six months ended ...
(Date:8/27/2014)... , Aug. 27, 2014  Columbia Laboratories, Inc. ... a provider of pharmaceutical development, clinical trial manufacturing, and ... today announced that it will participate at the upcoming ... Conference, to be held in New York ... at 11:15am on September 9, 2014 at the New ...
(Date:8/27/2014)... "Fatty Liver Disease Global Clinical Trials Review, H2, 2014″ ... scenario. This report provides elemental information and data relating ... . It includes an overview of the trial numbers ... trial conduction across the globe. The databook offers a ... trial status, prominence of the sponsors and also provides ...
Breaking Medicine Technology:Sihuan Pharmaceutical Announces 2014 Interim Results 2Sihuan Pharmaceutical Announces 2014 Interim Results 3Sihuan Pharmaceutical Announces 2014 Interim Results 4Sihuan Pharmaceutical Announces 2014 Interim Results 5Sihuan Pharmaceutical Announces 2014 Interim Results 6Sihuan Pharmaceutical Announces 2014 Interim Results 7Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 2Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 3Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 4Fatty Liver Disease Therapeutics Clinical Trials Market Review 2014 Analysis Report Available at MarketOptimizer.org 5
... Medical Systems Ltd. (NASDAQ: DHRM) ("Dehaier" or ... assembly, marketing and sale of medical devices and ... plans to release its financial results for the ... 31, 2011 on Monday, March 19, 2012, after the stock ...
... Timothy C. Tyson, Aptuit Chairman, announced that effective immediately, ... Operating Officer of Aptuit LLC. Following the recent sale ... has been promoted from his previous position at Aptuit ... Needleman is responsible for all day-to-day operations of the ...
Cached Medicine Technology:Dehaier Medical Systems Schedules 2011 Fourth Quarter and Full Year Financial Results and Conference Call 2Dehaier Medical Systems Schedules 2011 Fourth Quarter and Full Year Financial Results and Conference Call 3Aptuit LLC Names Stuart E. Needleman as President and Chief Operating Officer 2
... is ideal for all liquid handling applications ... operating buttons, and various dispensing techniques such ... make this a lab favorite. It intuitively ... pipette without any adverse effects on the ...
Single channel module for Finnpipette Biocontrol - Universal handle sold separately...
... the ease and comfort you've come to expect ... in clinical trials agreed that the BD Lancet ... settings allow you to choose the best lancet ... lancets, the device also helps eliminate the "vibrations" ...
... StaRRsed-III is a system that measures ... samples. This rate may be relevant ... The sedimentation rate is measured in ... typically used in high-volume settings such ...
Medicine Products: