Navigation Links
Drug Duo May Help Fight Aggressive Form of Breast Cancer
Date:1/17/2012

By Kathleen Doheny
HealthDay Reporter

TUESDAY, Jan. 17 (HealthDay News) -- Combining two drugs that target an aggressive type of breast cancer known as HER2-positive appears to work better than using either drug alone, researchers report.

The dual-drug approach greatly boosted the chances of eliminating microscopic signs of early cancer by the time a woman was due to have surgery, said researcher Dr. Jose Baselga, chief of hematology/oncology at Massachusetts General Hospital Cancer Center and a professor of medicine at Harvard Medical School.

The study was published online Jan. 17 in The Lancet.

The two drugs are Tykerb (lapatinib) and Herceptin (trastuzumab). Using both together resulted in a 51 percent response, compared with a 30 percent response in women given Herceptin alone. Those given Tykerb alone had a 25 percent response.

"What we observed was a massive improvement in response," Baselga said.

GlaxoSmithKline, the maker of Tykerb, helped fund the study.

"Lapatinib was approved for advanced breast cancer in 2007," Baselga said. "The question we had was, what is the efficacy if we give it in early-stage breast cancer prior to surgery?"

Baselga and his colleagues conducted a trial treating 455 women from 23 countries. All had HER2-positive breast cancers. All had tumors larger than about three-fourths of an inch.

In HER2-positive breast cancer, test results are positive for a protein called human epidermal growth factor receptor 2, which promotes cancer cell growth.

In the study, 154 women got Tykerb, 149 Herceptin and the other 152 both drugs. All had the drug regimen before surgery, with Taxol (paclitaxel), a standard chemotherapy, added after six weeks. After 12 more weeks of treatment, the women had surgery.

At that point, researchers evaluated who had better responses. The women continued the treatments for one more year, allowing researchers to foll
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. MARA Fights Malaria With WaveMaker and Amazon Web Services
2. NASBE Supports First Lady Michelle Obama in Fight Against Childhood Obesity
3. Planting Seeds to Fight Childhood Obesity
4. AMA Joins First Lady in Fight Against Childhood Obesity
5. A common cholesterol drug fights cataracts, too
6. In Support of the Lets Move Campaign to Fight Childhood Obesity, Verizon Thinkfinity Providing Free Educational Resources on Nutrition and Exercise
7. The Alliance for a Healthier Generation Names Celtics Captain Paul Pierce National Athlete Spokesperson in the Fight Against Childhood Obesity
8. Tiny fruit fly could offer big clues in fight against obesity, researcher says
9. Family's Fight to Save Child Spreads Hope Around Globe
10. Businesses Rally Big Efforts to Benefit the Susan G. Komen Phoenix Affiliates Fight Against Breast Cancer
11. 29 Clear Channel stations Nationwide Raise Nearly $2.8 Million to Help Save the Lives of Kids Fighting Cancer and Other Deadly Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Duo May Help Fight Aggressive Form of Breast Cancer 
(Date:4/17/2014)... vaccine brands for children may not be the most ... factors when choosing vaccines, driving the market toward what ... new study by University of Illinois researchers. , "The ... numerous factors," says Sheldon H. Jacobson, a co-author of ... of mathematics at the U. of I. "In an ...
(Date:4/17/2014)... Diego School of Medicine report that older women, plucky ... loss are more likely to be compassionate toward strangers ... in this month,s issue of the International Journal ... associated with better health and well-being as we age, ... the outcomes of individuals whose deficits in compassion put ...
(Date:4/17/2014)... Pediatrician-in-Chief Jon McCullers, MD, was recently invited to ... Nature Reviews Microbiology , one of the ... world-renowned infectious disease specialist, and chair of the ... Health Science Center, analyzed the epidemiology and microbiology ... pandemics, as well as more recent 2009 novel ...
(Date:4/17/2014)... who treat patients with a severe and progressive ... agonizing treatment decision. , The drug sirolimus can ... shortness of breath. But some patients eventually may ... fatal complications following transplantation. , "It,s a terrible ... of Loyola University Medical Center,s LAM Clinic and ...
(Date:4/17/2014)... IL, April 17, 2014-- Colic affects about one in ... for numerous pediatric visits during the first several months ... colic symptoms was showing promise; however, the April 1, ... (BMJ2014;348:g2107; Sung, Valerie) reported on a study, "Probiotics and ... L reuteri for infant colic did ...
Breaking Medicine News(10 mins):Health News:Study recalculates costs of combination vaccines 2Health News:The ilk of human kindness 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2
... Saving Benefit Faces Eventual Elimination Without Relief , ... of President Obama,s pledge not to raise taxes on the ... outside of the normal legislative process -- adopting provisions approved ... the use of flexible spending accounts (FSAs) in order to ...
... from a new virtual reality training programme created at ... have been working with researchers in the School of ... scenarios that test expert players, perceptual skills. Lead ... Senior Lecturer in Visual Perception who has previously collaborated ...
... to educate, inform, and empower the people of Chicago, ... its 25-minute live call-in show, "Community Health," on ... at 6:00 PM on Channel 21. , ... Health Clinics with Erin Buckley, FNP-C, Certified Family Nurse ...
... Oct. 14 Peter Sheldon, Vice President of Operations ... commercial cleaning businesses, will be a featured speaker at ... to be held on October 14-15 at The Fairmont ... is "Be the Best in Your Business with Best ...
... 15, 2009 marks the 35th anniversary of the founding of ... McDonald Houses in 52 countries and regions throughout the world, ... the Philadelphia House,s two locations (on Chestnut Street, and at ... McDonald House of Southern New Jersey, the world,s 51st House, ...
... ... a few years ago, today it seems "Natural" is the new buzz word in retail, ... Buster was recently featured on an episode of The Dr. Oz Show in a segment ... ...
Cached Medicine News:Health News:Fight to Preserve Flexible Spending Accounts Moves to the House of Representatives 2Health News:Fight to Preserve Flexible Spending Accounts Moves to the House of Representatives 3Health News:Increased success a 'virtual' certainty for rugby players 2Health News:Retail Health Clinics - The Real Story 2Health News:Coverall Executive Peter Sheldon To Be Featured Speaker at PRSM Mid-Year Conference 2Health News:Philadelphia-Born Ronald McDonald House(R) Program Celebrates 35 Years 2Health News:Philadelphia-Born Ronald McDonald House(R) Program Celebrates 35 Years 3Health News:Sinus Buster Paves the Way for Natural OTC Products and Mainstream Success 2
(Date:1/15/2014)... 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting ... China,s orthopedic instrument industry has ... size rising from 3.28 billion yuan in 2006 to ...
(Date:1/15/2014)... 2014  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) has announced ... Global Industry Analysis, Size, Share, Growth, Trends And Forecast, ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) ... patients in order to treat dental impairments, for tooth ...
(Date:1/15/2014)... AARP Foundation today announced it has established a relief ... cold weather that has gripped much of the nation. AARP ... so to support these emergency relief efforts AARP and AARP ... mean up to $500,000 in aid. The matching program will ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3
... LAS VEGAS, Jan. 10, 2012 What: ... the Consumer Electronics Show (CES) in Las Vegas.  The Ion ... one day for $1,000 When:   Tuesday, ... hours Where:   Las Vegas Convention Center, ...
... Jan. 10, 2012   Reportlinker.com announces that a new ... The Outlook for Medical Devices ... .html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Devices 66 Key Markets Covered ... device market will approach US$350 billion, an annual ...
Cached Medicine Technology:The Outlook for Medical Devices Worldwide 2
... containment system work station has a ... panel hinges from top and covers ... The sides and front are made ... to most chemicals. Comes complete ...
Reusable shielded cable...
Surgical-grade stainless steel disposable concentric needle with Trocar tip has an insulated platinum-alloy core and two attached 61-cm (24-in) lead wires. Needles sold in packages of 20....
... The RSV OIA test features a dual-detection ... results. Approved for children under age 5 ... an answer in just over 15 minutes. ... enable you to decrease costs for unnecessary ...
Medicine Products: