Navigation Links
Drug Delivery in Central Nervous System Diseases - 2013 Market Report
Date:3/22/2013

Dublin, Ireland (PRWEB) March 22, 2013

The delivery of drugs to central nervous system (CNS) is a challenge in the treatment of neurological disorders. Drugs may be administered directly into the CNS or administered systematically (e.g., by intravenous injection) for targeted action in the CNS. The major challenge to CNS drug delivery is the blood-brain barrier (BBB), which limits the access of drugs to the brain substance.

Advances in understanding of the cell biology of the BBB have opened new avenues and possibilities for improved drug delivery to the CNS. Several carrier or transport systems, enzymes, and receptors that control the penetration of molecules have been identified in the BBB endothelium. Receptor-mediated transcytosis can transport peptides and proteins across the BBB. Methods are available to assess the BBB permeability of drugs at the discovery stage to avoid development of drugs that fail to reach their target site of action in the CNS.

Various strategies that have been used for manipulating the blood-brain barrier for drug delivery to the brain include osmotic and chemical opening of the blood-brain barrier as well as the use of transport/carrier systems. Other strategies for drug delivery to the brain involve bypassing the BBB. Various pharmacological agents have been used to open the BBB and direct invasive methods can introduce therapeutic agents into the brain substance. It is important to consider not only the net delivery of the agent to the CNS, but also the ability of the agent to access the relevant target site within the CNS. Various routes of administration as well as conjugations of drugs, e.g., with liposomes and nanoparticles, are considered. Some routes of direct administration to the brain are non-invasive such as transnasal route whereas others involve entry into the
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Women's Excellence in Pelvic Floor Physical Therapy Near Pontiac, MI, Now Offers Therapy After Vaginal Delivery to Prevent Urinary Incontinence, Improve Sexual Function
2. Pregnant womens likelihood of cesarean delivery in Massachusetts linked to choice of hospitals
3. Service Delivery Platform (SDP) Market is Growing at a CAGR of 9.15% & to Reach $6.94 Billion by 2018 - New Report by MarketsandMarkets
4. U of M researchers find wide variation in cesarean delivery rates among US hospitals
5. Research and Markets - Drug Delivery in Cancer - Technologies, Markets and Companies - 2013 Report
6. Mussel-inspired glue for surgical repair and cancer drug delivery
7. The USPS Has Announced No Saturday Delivery and Increased Postage Again - How Does This Affect the World of Marketing?
8. Surgical Delivery of Drug Shows Promise Against Bleeding Stroke
9. No increase in brain aneurysm rupture risk during pregnancy and delivery
10. Electronic nicotine delivery systems could help reduce smoking
11. NHPCO Brings 100 Hospice Leaders Together to Create Future Care Delivery Models
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... USA Medical Card, a ... week to coincide with back-to-school and the start of “sick season” for many ... elementary school children are sick an average of 8 to 12 times each ...
(Date:9/1/2015)... ... September 01, 2015 , ... Éminence Organic Skin ... the VitaSkin™ Exfoliating Peels. This revolutionary collection of natural peel solutions complements the ... Clear. , Formulated with alpha hydroxy acids and natural active ingredients, these ...
(Date:9/1/2015)... , ... September 01, 2015 , ... Dr. Trace Curry ... JourneyLite of Cincinnati. In the last month the FDA has approved two intra-gastric ... ™. These procedures represent the first incisionless, reversible, weight loss procedures available to ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... for Alfresco, a next-generation customer communications archiving solution integrated with Alfresco‘s enterprise ... from Crawford and helps organizations save millions of dollars in printing costs ...
(Date:9/1/2015)... ... September 01, 2015 , ... Award-winning ... pick-up artists about their experiences of female beauty, women’s emotions, fertility, female violence ... issues, as well as their relationships with other men, documenting how the power ...
Breaking Medicine News(10 mins):Health News:USA Medical Card Launches New FAQ Video During Back-to-School 2Health News:Éminence Organic Skin Care Introduces Results-Oriented Exfoliating Peels for Every Skin Type 2Health News:Éminence Organic Skin Care Introduces Results-Oriented Exfoliating Peels for Every Skin Type 3Health News:Dr. Trace Curry Performs First ORBERA™ Intra-gastric Balloon in Ohio at JourneyLite, a New Incisionless Option For The Treatment of Obesity 2Health News:Introducing Next-Generation Archiving Solution PRO Archiver for Alfresco® 2Health News:Introducing Next-Generation Archiving Solution PRO Archiver for Alfresco® 3Health News:Female Porn Director Explains Male Insecurities about Women in a New Book 2
... Psoriasis Cure Now has,selected its $7,500 Grand Prize winner ... Monica, California walks away with the big prize,after a ... other,Finalists each will receive $250 in the contest. The ... ., "Brendan Hayward captured, in just 30 ...
... 12 International,Isotopes Inc. (OTC Bulletin Board: INIS) ... months ending September 30, 2007. REVENUE: Revenue ... 2007, was $1,486,112 and $3,592,049 respectively, as compared ... 2006. These numbers,represent an increase of 2% for ...
... health care risk,management and insurance provider FinCor Holdings ... ended Sept. 30, 2007, including significant,increases in net ... of the year. The privately held Lansing, ... risk management products,and services for health care providers ...
... HLM Venture Partners announced today,that it has led ... Inc. CaseNET, based in Waltham, MA, is an early-stage ... government,agencies a software solution for medical and care management. ... to the round and was joined,by existing investors Sigma ...
... 12 The American Medical,Association (AMA) proudly presented ... Service Award Saturday at its semi-annual,policy-making meeting. Dr. ... award, which is granted for meritorious service in ... has devoted himself to advancing medical education," said,AMA ...
... 12 Dileep G. Bal, M.D.,received the 2007 ... AMA Foundation, the award recognizes physicians who have ... activities. The,award was presented to Dr. Bal, a ... during the opening session of the AMA,s semi-annual,policy-making ...
Cached Medicine News:Health News:Psoriasis Cure Now Video Contest $7,500 Grand Prize Winner Announced 2Health News:International Isotopes Inc. Announces Third Quarter and Nine Months 2007 Financial Results 2Health News:International Isotopes Inc. Announces Third Quarter and Nine Months 2007 Financial Results 3Health News:International Isotopes Inc. Announces Third Quarter and Nine Months 2007 Financial Results 4Health News:FinCor Holdings Posts Double-Digit Increases in Revenue and Net Income for Third Quarter 2Health News:FinCor Holdings Posts Double-Digit Increases in Revenue and Net Income for Third Quarter 3Health News:HLM Venture Partners Leads Series B Financing of CaseNET, Inc. 2Health News:Portland Physician Wins AMA Distinguished Service Award 2Health News:AMA Foundation Honors Hawaii Physician 2
(Date:8/31/2015)... The Indiana Medical Device Manufacturers Council and ... Sciences Policy Forum to state legislators. The new policy ... Diagnostics in Indianapolis and featured ... Ellspermann and State Sen. Brandt Hershman . ... new Learning & Development Center, which is under construction ...
(Date:8/31/2015)... DALLAS , Aug. 31, 2015  Ascendant Solutions, ... "Company") today announced that its Healthcare subsidiary, Dougherty,s Holdings, ... located on the downtown square of Springtown, ... more than 35 years, this community-based pharmacy has provided ... residents of Springtown . ...
(Date:8/31/2015)... August 31, 2015 A ... global cardiovascular monitoring and diagnostic devices market stood ... to reach a value of approximately US$7.0 billion ... between 2013 and 2019. The title of the ... (ECG, Holter Monitors, Event Monitors, Cardiovascular Diagnostic Catheters, ...
Breaking Medicine Technology:Indiana Lt. Gov. Sue Ellspermann and State Sen. Brandt Hershman Kick Off New Life Sciences Policy Series 2Indiana Lt. Gov. Sue Ellspermann and State Sen. Brandt Hershman Kick Off New Life Sciences Policy Series 3Ascendant Solutions, Inc. Announces Completion of Fifth Pharmacy Acquisition by Its Dougherty's Holdings Subsidiary 2Ascendant Solutions, Inc. Announces Completion of Fifth Pharmacy Acquisition by Its Dougherty's Holdings Subsidiary 3Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 2Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 3Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 4Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 5
...  ERT (Nasdaq: ERT ), announced today that ... is scheduled to present at the Citi 2012 Global ... 2012 in New York. Interested parties may ... at http://www.ert.com . The webcast may also be ...
... a leading developer of stereotactic radiosurgery and cancer ... CyberKnife cancer center, which will begin treating patients ... through a partnership between Accelitech, physicians and Swedish ... Chicago will provide state-of-the-art CyberKnife treatment to patients ...
Cached Medicine Technology:ERT to Present at the Citi 2012 Global Health Care Conference February 29, 2012 2Accelitech to Open the First CyberKnife Cancer Center Within the City of Chicago 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: