Navigation Links
Drug Could Raise Risk of Heart Attack Among Type 2 Diabetes Patients
Date:9/18/2013

Pomona, CA (PRWEB) September 18, 2013

College of Pharmacy assistant professor Olivia J. Phung, PharmD, has published an article proposing that using a certain class of diabetes medication could potentially increase risk of heart attack and other cardiovascular problems.

The article, published in the journal Diabetic Medicine on Sept. 16, 2013, was a meta-analysis combining evidence from 33 studies to show an association with increased cardiovascular events when using this class of drug.

Phung and her WesternU team were funded by Merck to evaluate long-term use of sulfonylureas, a group of drugs that lower the amount of glucose in blood, and to find evidence behind the warnings on package insert labels that say that there is an increase in cardiovascular occurrences with these drugs.

“These results show that there is evidence of a potential association of this drug and potential harm to the patient with increased cardiovascular events,” said Phung. “It’s important for clinicians to be familiar with this so that they can be aware of the potential benefits and harms when prescribing these drugs.”

The finding warrants consideration in clinical practice when other treatment options may be available, Phung said.

“Diabetes itself is already a risk factor for increased cardiovascular events, so we don’t want to be adding to that,” Phung said.

The American Diabetes Association (ADA) recommends initial metformin as a drug therapy for most newly diagnosed Type 2 diabetes patients. Sulfonylureas remain one of the most commonly prescribed add-on therapies when treatment with metformin by itself is insufficient to reach recommended targets, Phung reported in her paper.

Phung said that the study does not provide enough evidence to show a direct cause-and-effect relationship. Rather, with these mostly observational studies, there is evidence of an association.

College of Pharmacy assistant professor Emmanuelle Schwartzman, PharmD, CDE, and Robert Allen, PharmD ’12, who was a fourth-year student at the time of the review, were key contributors to the study.

###

Western University of Health Sciences (http://www.westernu.edu), located in Pomona, Calif. and Lebanon, Ore., is an independent nonprofit health professions university, conferring degrees in biomedical sciences, dental medicine, health sciences, medical sciences, nursing, optometry, osteopathic medicine, pharmacy, physical therapy, physician assistant studies, podiatric medicine and veterinary medicine. The Chronicle of Higher Education named WesternU a Great College to Work For in 2012 and 2013.

Read the full story at http://www.prweb.com/releases/2013/9/prweb11137368.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Red wine, fruit compound could help block fat cell formation
2. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
3. Report says new evidence could tip the balance in aspirin cancer prevention care
4. Climate Change Could Be Tough on Seniors Health: Study
5. Could Menthol Cigarettes Pose Even Higher Stroke Risk?
6. Online Tool Could Diagnose Autism Quickly, Developers Say
7. Codeine After Surgery Could Endanger Certain Kids: Study
8. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
9. Discovery could help to develop drugs for organ transplant and cancer patients
10. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
11. Saliva test could dramatically increase detection of oral cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is ... vendors and unique items from across the nation, this holiday-themed event will raise funds ... by the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... viewers the lowdown on sciatica in a new episode of "Success Files," which ... current events and innovation and investigates each subject in-depth with passion and integrity. ...
(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... their devotion to personalized service, SMP Pharmacy Solutions announces their ... South Florida Business Journal,s 50 Fastest-Growing Companies, and listed for ... specialty pharmacy has found its niche.  To that end, the ... by SFBJ as the 2017 Power Leader in Health Care. ... award in October, Bardisa said of the three achievements, "It,s ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium ... Master File solutions, today—from the IQPC Trial Master ... , NL)—announced that EastHORN Clinical Services has ... clinical programs and TMF management. EastHORN, a leading ... eTMF platform to increase transparency to enable greater ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
Breaking Medicine Technology: