Navigation Links
Drug Could Raise Risk of Heart Attack Among Type 2 Diabetes Patients
Date:9/18/2013

Pomona, CA (PRWEB) September 18, 2013

College of Pharmacy assistant professor Olivia J. Phung, PharmD, has published an article proposing that using a certain class of diabetes medication could potentially increase risk of heart attack and other cardiovascular problems.

The article, published in the journal Diabetic Medicine on Sept. 16, 2013, was a meta-analysis combining evidence from 33 studies to show an association with increased cardiovascular events when using this class of drug.

Phung and her WesternU team were funded by Merck to evaluate long-term use of sulfonylureas, a group of drugs that lower the amount of glucose in blood, and to find evidence behind the warnings on package insert labels that say that there is an increase in cardiovascular occurrences with these drugs.

“These results show that there is evidence of a potential association of this drug and potential harm to the patient with increased cardiovascular events,” said Phung. “It’s important for clinicians to be familiar with this so that they can be aware of the potential benefits and harms when prescribing these drugs.”

The finding warrants consideration in clinical practice when other treatment options may be available, Phung said.

“Diabetes itself is already a risk factor for increased cardiovascular events, so we don’t want to be adding to that,” Phung said.

The American Diabetes Association (ADA) recommends initial metformin as a drug therapy for most newly diagnosed Type 2 diabetes patients. Sulfonylureas remain one of the most commonly prescribed add-on therapies when treatment with metformin by itself is insufficient to reach recommended targets, Phung reported in her paper.

Phung said that the study does not provide enough evidence to show a direct cause-and-effect relationship. Rather, with these mostly observational studies, there is evidence of an association.

College of Pharmacy assistant professor Emmanuelle Schwartzman, PharmD, CDE, and Robert Allen, PharmD ’12, who was a fourth-year student at the time of the review, were key contributors to the study.

###

Western University of Health Sciences (http://www.westernu.edu), located in Pomona, Calif. and Lebanon, Ore., is an independent nonprofit health professions university, conferring degrees in biomedical sciences, dental medicine, health sciences, medical sciences, nursing, optometry, osteopathic medicine, pharmacy, physical therapy, physician assistant studies, podiatric medicine and veterinary medicine. The Chronicle of Higher Education named WesternU a Great College to Work For in 2012 and 2013.

Read the full story at http://www.prweb.com/releases/2013/9/prweb11137368.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Red wine, fruit compound could help block fat cell formation
2. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
3. Report says new evidence could tip the balance in aspirin cancer prevention care
4. Climate Change Could Be Tough on Seniors Health: Study
5. Could Menthol Cigarettes Pose Even Higher Stroke Risk?
6. Online Tool Could Diagnose Autism Quickly, Developers Say
7. Codeine After Surgery Could Endanger Certain Kids: Study
8. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
9. Discovery could help to develop drugs for organ transplant and cancer patients
10. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
11. Saliva test could dramatically increase detection of oral cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Pa. (PRWEB) , ... October 13, 2017 , ... While ... dark poses a problem. Fortunately, an inventor from Austin, Texas, has identified a solution. ... to medication in darkness or restricted lighting. As such, it eliminates the need to ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & Associates ... special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to date ... elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded by ...
(Date:10/13/2017)... ... 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out ... free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting ... children of all ages; it is a non-competitive, non-timed event, which is all about ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history ... The Brink” is the creation of published author, William Nowers. Captain Nowers and ... WWII veteran, he spent thirty years in the Navy. Following his career as ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Divoti USA will engrave and process all non-coated ... latest FDA requirements, which stipulates new criteria regarding medical device manufacture ... Medical ID jewelry such as Medical ID Bracelets, can rest assured ... of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving process ...
(Date:10/11/2017)... 11, 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), ... in Las Piedras, Puerto Rico , ... Following a ... sustained minor structural damage, temporary loss of power and ... been completed, manufacturing operations have resumed, and the company ...
(Date:10/4/2017)... 2017  South Korean-based healthcare product Development Company I.M. ... on Kickstarter. The device will educate the user about ... better efficiency compared to the dated and pricey CPR ... efficacy of the compression for a more informed CPR ... to raise $5,000. ...
Breaking Medicine Technology: