Navigation Links
Drug Company-Funded Asthma Drug Studies More Positive

Expert review finds fewer adverse effects reported

TUESDAY, Oct. 23 (HealthDay News) -- Drug company-funded studies of asthma drugs called inhaled corticosteroids are less likely to find adverse effects than studies that were paid for by other sources, Spanish researchers say.

A team from Children's Hospital La Fe in Valencia analyzed 504 studies of the drugs conducted between 1993 and 2002.

Potentially harmful decreases in the stress hormone cortisol, decreases in bone mineral density, and growth suppression are among the adverse effects that have been associated with inhaled corticosteroids, the researchers note.

Of the 504 studies, 275 were funded by drug companies and 229 were funded by other sources, such as government agencies and non-profit organizations.

The researchers found that 34.5 percent of drug company-funded studies and 65.1 percent of studies funded by other sources identified significant differences in adverse events between patients who took inhaled corticosteroids and those in control groups who didn't take the drugs.

The researchers said the difference was no longer statistically significant when they factored in components of study design, such as dosage amounts or a focus limited to specific adverse effects. This suggests that the association between funding source and more positive findings may be the result of variations in how the studies were designed, said the researchers.

They noted that it's difficult to determine if drug company-funded studies are too positive or whether studies funded by other sources are too cautious.

Still, "having information on source of funding will help readers of these studies have a better informed and balanced judgment on the authors' interpretations," they concluded. "Disclosure of conflicts of interest should be strengthened for a more balanced opinion of the safety of drugs."

The study appears in the Oct. 22 issue of the journal Archives of Internal Medicine.

More information

The American Lung Association has more about asthma medications.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Oct. 22, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Drug for Bronchial Asthma
2. Asthma may actually be prevented by Dust and Dirt
3. Inhaled Steroids Safe & Effective for Children with Asthma
4. What happens when Asthmatics consume Aspirin?
5. Fireworks can spell death for asthmatic children
6. New vaccine helps allergy and asthma patients
7. New vaccine helps allergy and asthma patients
8. Nearly all asthma deaths preventable
9. Asthma! A new warning for heart disease
10. Soluble IL-4 Receptor - A new boon for asthmatics
11. Cats to protect children from asthma
Post Your Comments:
(Date:6/26/2016)... ... ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect Plugin ... whole new perspective by using the title layers in ProSlice Levels to split-up ... Levels contains over 30 Different presets to choose from. FCPX users can ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin ... injury. Recently, he has implemented orthobiologic procedures as a method for treating his ... of the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... ... Comfort Keepers® of San Diego, CA is excited to announce they are ... drive cancer patients to and from their cancer treatments. Comfort Keepers provides quality ... and ongoing independence. Getting to and from medical treatments is one of the ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the ... report to their offering. ... favourable commercial environment for MedImmune to enter. The US ageing ... serve to drive considerable growth for effective anti-influenza medications. The ... sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... -- , , , WHEN: , ... , , , LOCATION: , , , Online, with free ... EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice President ... Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... is witnessing an exceptional era. Several new demand spaces, such as ...
(Date:6/23/2016)... Ill. and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment ... Astellas Farma Brasil as the company,s second affiliate in Latin America . ... ... General Manager of Astellas Farma Colombia ... ...
Breaking Medicine Technology: