Navigation Links
Drug Combo Might Fight Aggressive Breast Cancer More Safely
Date:10/6/2011

ion leads to excess production of HER2 in the cancer cells.

The researchers evaluated disease-free survival and overall survival at five years. The addition of the one year of Herceptin improved both disease-free and overall survival. The disease-free survival rates at five years were 75 percent in the ACT group, 84 percent in the ACTH group and 81 percent in the TCH group.

Overall survival was 87 percent for the ACT group, 92 percent for the ACTH and 91 percent in the TCH group.

However, the rates of congestive heart failure and other cardiac problems were higher in the ACTH group than in the TCH group. Twenty-one of those on ACTH had congestive heart failure, compared with four in the TCH group.

There were fewer reports of side effects such as joint pain and vomiting with the TCH group compared with the ACTH group, Slamon found. "And you get comparable effects," he noted.

Sanofi-Aventis and Genentech (which makes Herceptin) funded the study; Slamon reports receiving honoraria and reimbursement for travel expenses from both companies.

The latest report echoes findings from several previous ones, Slamon said. Doctors have been using the TCH regimen in women at risk for cardiac problems; it is approved by the U.S. Food and Drug Administration. "We're saying it should be used for everybody," Slamon said. "We are saying we think it is the standard of care, with comparable effects, and you lose all the anthracycline toxicity."

However, Dr. Daniel F. Hayes, clinical director of the breast oncology program at the University of Michigan Comprehensive Cancer Center in Ann Arbor, disagreed.

"I think TCH is a standard of care, it's not the standard of care," he said.

"Herceptin itself can cause heart failure," Hayes said. In the study, there were fewer cases of it in those who got Herceptin without anthracyclines, but it did still occur.

He suggests a risk-adapted approach, in which a doctor would decide which
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
2. New Combo Therapy May Prevent TB, Save Lives in People With HIV
3. Vitamin D, Calcium Combo May Halve Melanoma Risk in Some Women
4. Energy Drink-Vodka Combo Nearly Kills Teen
5. Daily Four-Drug Combo Pill Halves Heart Disease Risk: Study
6. Combo of Paxil, Pravachol May Raise Blood Sugar
7. Chemo Combo May Help Stave Off Pancreatic Cancer Death
8. Alcohol-Energy Drink Combo Riskier Than Booze Alone, Study Says
9. Low-Intensity Exercise, Drug Combo Can Help Parkinsons Patients, Studies Show
10. Diet-Exercise Combo Seems to Work Best for Obese Seniors
11. Risks May Outweigh Benefits for Blood Pressure Drug Combo
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Combo Might Fight Aggressive Breast Cancer More Safely
(Date:12/26/2014)... Angeles, CA (PRWEB) December 26, 2014 ... power score of 3.1 out of 5. This score ... a low level of product specialization, low switching costs ... power is reduced by the low availability of substitutes ... the world price of steel and aluminum, key inputs ...
(Date:12/26/2014)... 2014 “Many people become overwhelmed by ... claim issues and phone calls with insurance companies,” The ... featuring their free eBook on pedestrian and bicycle ... pedestrian and bicycle auto accident claims assures the injured ... of professionally handling their case while they focus on ...
(Date:12/26/2014)... Phoenix, AZ (PRWEB) December 26, 2014 ... dependable source for the best in heating, cooling ... demand for 24 hour emergency services in 2014 ... customers alike know that Arizona is known for ... contractor company that understands the intricacies and details ...
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) – ... the current treatment landscape, unmet needs, current pipeline ... Stivarga is a drug which is used in ... Ingelheim is developing nintedanib (BIBF-1120), an orally available ... in the US, Europe, and Japan. The drug ...
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of ... its new selection of black one-shoulder cocktail dresses . ... they are available at discounted prices, up to 70% off. ... last for three weeks only. You know, we have thousands ... interested in our new items can visit our website for ...
Breaking Medicine News(10 mins):Health News:Cooking & Warming Equipment Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Cooking & Warming Equipment Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2
... N.J., Dec. 3 Covance Inc. (NYSE:,CVD), a ... leading,humanitarian organization, announced today that they are partnering ... for,Orphans and Vulnerable Children in Rwanda. Covance will ... day care centers for,children ages two to four ...
... protect cells from the powerful, common chemotherapeutic agent doxorubicin ... the drug also can destroy the heart., We found ... cell survival in the face of doxorubicin, says Dr. ... Georgia Cancer Center. At the moment you start inactivating ...
... debate , MONDAY, Dec. 3 (HealthDay News) -- There,s ... the risk of developing multiple sclerosis (MS) in childhood, a ... investigated a possible association between the hepatitis B vaccine and ... short- or long-term risk of MS. However, the studies ...
... HARBOR, N.Y. (Mon., Dec. 3, 2007) Two ... early embryogenesis are featured in this months release of ... which are freely accessible online ( www.cshprotocols.org ), describe ... These cell-tagging techniques, combined with sophisticated imaging methods, ...
... As momentum continues to,build on the issue of ... the Pharmaceutical Care Management Association,(PCMA) today announced a ... Ph.D., Sc.D., Last year, Dr. Bootman co-chaired ... all physicians begin using e-prescribing by,2010 to help ...
... and HUNTSVILLE, Ala., Dec. 3 Operon,Biotechnologies, Eurofins ... the,Eurofins Genomics network - announced today that they ... a new worldwide leader in the competitive,custom oligonucleotide ... state of,the art high-throughput production facilities in all ...
Cached Medicine News:Health News:Covance and Care Partner on Rwanda Early Childhood Development Initiative 2Health News:Covance and Care Partner on Rwanda Early Childhood Development Initiative 3Health News:Genes identified that protect against heart damage from chemotherapy 2Health News:No Link Between Hepatitis B Shot, MS: Study 2Health News:Cold Spring Harbor Protocols features innovative methods for embryology research 2Health News:MWG and Operon Are Joining Forces 2
(Date:12/24/2014)... BEIJING , Dec. 24, 2014  The International Trade ... by ResMed (RMD) against BMC Medical. In a notice issued ... and found that ResMed,s patent on its humidifier was invalid. ... decision a "monumental win". "We are very excited with the ... the position that we have taken since the very beginning ...
(Date:12/24/2014)... LONDON , December 24, 2014 /PRNewswire/ ... expected to grow at an average rate of 8.1%. ... and volume. Hip, knee and spine surgeries are the ... emerging economies they have a lower penetration. Increased number ... use of composites. Non-metallic orthopedic devices have gained popularity ...
(Date:12/24/2014)... ResMed (NYSE: RMD ) today announced ... medical device manufacturer BMC Medical Co., Ltd. ... listed below infringe ResMed,s patents, and entered an order prohibiting ... the United States : , iVolve ... Willow nasal pillows mask , iVolve full face mask ...
Breaking Medicine Technology:ITC Final Decision Goes Against ResMed (RMD) Monumental Win for 3B/BMC 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2
... VIEW, Calif., Sept. 16 Based on its recent ... market, Frost & Sullivan recognizes Accelrys, Inc., with the ... Product Innovation of the Year. The company has merited ... a solution that provides, for the first time, a ...
... (LIG) (Pink Sheets: LIGA ), a Dallas-based ... cleaner and disinfectant for the masks of CPAP (continuous ... for patients suffering from sleep apnea. The ... by Jones Products Company, LLC, which is 51% owned ...
Cached Medicine Technology:Frost & Sullivan Acknowledges Accelrys for Scientific Informatics Solution 2Frost & Sullivan Acknowledges Accelrys for Scientific Informatics Solution 3Frost & Sullivan Acknowledges Accelrys for Scientific Informatics Solution 4LIG Assets, Inc. Begins Distribution and Marketing of Unique CPAP Mask Cleaner 2LIG Assets, Inc. Begins Distribution and Marketing of Unique CPAP Mask Cleaner 3
... new Finnpipette Focus from Thermo ... combine ergonomics with uncompromising performance. ... plate offers a custom fit ... new shorter tip cones allow ...
... The Eppendorf Reference Series 2000 Pipette is ... stroke, a compact and robust design, and ... is used to operate the measuring stroke ... tip. Product features:Eppendorf "pipette/tip" system ensures utmost ...
Inquire...
... precision, ergonomics, and value!, Comfortable ... soft non-slip, contoured handle , Finer ... plunger spring action , Completely autoclavable ... the need for recalibration , Easy-to-read ...
Medicine Products: