Navigation Links
Drug Combo Might Fight Aggressive Breast Cancer More Safely
Date:10/6/2011

By Kathleen Doheny
HealthDay Reporter

WEDNESDAY, Oct. 5 (HealthDay News) -- Treating women with an aggressive form of early stage breast cancer using Herceptin and chemotherapy, while not turning to a third type of drug known as an anthracycline, improves survival while posing less danger to the heart, researchers report.

They tested three different regimens, one of which did not include any anthracyclines. When Herceptin is given with doxorubicin (Adriamycin), an anthracycline, toxic cardiac effects have been seen.

"What the study shows is you have comparable effectiveness in a Herceptin-based regimen when you don't use the anthracyclines," said Dr. Dennis Slamon, director of clinical and translational research at the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles. Earlier research of his led to the development of Herceptin (trastuzumab).

He contends that the new regimen should be the new standard of care, but one expert who wrote an accompanying commentary disagreed.

The new study is published in the Oct. 6 issue of the New England Journal of Medicine.

Slamon and his colleagues from the Breast Cancer International Research Group tested one of three different treatments in 3,222 women who had HER2-positive early-stage breast cancer. This breast cancer is more aggressive and is linked with a worse outlook and shorter survival times.

One group got a regimen called ACT-- the standard therapy of doxorubicin (Adriamycin) and paraplatin (Carboplatin) followed by docetaxel (Taxotere). A second group got that same standard regimen plus a year of Herceptin -- called ACTH. The third group got the anthracycline-free regimen, called TCH -- doxetaxel (Taxotere) and paraplatin (Carboplatin) with a year of Herceptin.

Herceptin targets HER2, a protein known as human epidermal growth factor receptor 2. In about one of five breast cancers, a gene mutat
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
2. New Combo Therapy May Prevent TB, Save Lives in People With HIV
3. Vitamin D, Calcium Combo May Halve Melanoma Risk in Some Women
4. Energy Drink-Vodka Combo Nearly Kills Teen
5. Daily Four-Drug Combo Pill Halves Heart Disease Risk: Study
6. Combo of Paxil, Pravachol May Raise Blood Sugar
7. Chemo Combo May Help Stave Off Pancreatic Cancer Death
8. Alcohol-Energy Drink Combo Riskier Than Booze Alone, Study Says
9. Low-Intensity Exercise, Drug Combo Can Help Parkinsons Patients, Studies Show
10. Diet-Exercise Combo Seems to Work Best for Obese Seniors
11. Risks May Outweigh Benefits for Blood Pressure Drug Combo
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Combo Might Fight Aggressive Breast Cancer More Safely
(Date:6/30/2015)... ... June 30, 2015 , ... CCAR is pleased to announce its ... in Hartford, Willimantic and Bridgeport. This month, staff member Jim Higgins left his ... He is excited to take on this role of organizing peer recovery support ...
(Date:6/30/2015)... Los Angeles, CA (PRWEB) , ... June 30, ... ... Physicians News Digest discussed the advantages that fat transfer procedures had ... breast reconstruction using fat transfer techniques create breasts that “look and feel natural,” ...
(Date:6/30/2015)... GA (PRWEB) , ... June 30, 2015 , ... After ... by the U.S. Food and Drug Administration, GlobalSun (TM) — sunscreen specifically formulated for ... with an SPF rating of 35, hits the market just in time to help ...
(Date:6/30/2015)... ... June 30, 2015 , ... ... response profiling test to help oncologists provide personalized cancer treatment, will be ... assay provides the oncologist with valuable insight on how a specific patient’s ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... ... medical device market research, has launched a new reimbursement insurance policy tracking and ... professionals to receive US insurance policy and rate updates in real-time from hundreds ...
Breaking Medicine News(10 mins):Health News:The Connecticut Community for Addiction Recovery takes Recovery Coaching to a new level 2Health News:Recent Article Advocating for Breast Reconstruction with Fat Transfers Successfully Outlines the Advantages of Transfer Procedures, Notes Beverly Hills Physicians 2Health News:Recent Article Advocating for Breast Reconstruction with Fat Transfers Successfully Outlines the Advantages of Transfer Procedures, Notes Beverly Hills Physicians 3Health News:GlobalSun – The First Sunscreen Developed for All People of Color – Hits The Market 2Health News:Correct Chemo Joins NextGxDx Online Genetic Testing Marketplace 2Health News:Correct Chemo Joins NextGxDx Online Genetic Testing Marketplace 3Health News:iData Research Introduces New Medical Insurance Reimbursement Policy & Rate Tracker Subscription Service 2
... Fla., Jan. 7 - 3M, in,partnership with Roush Fenway Racing, ... paint scheme to the American Red Cross for two races,during ... space on the,rear side panel of the car where the ... year., (Photo: http://www.newscom.com/cgi-bin/prnh/20080107/DC10974 ), "This is ...
... WellPoint, Inc. (NYSE: WLP ) today,announced that ... Technology,and Government Services Business Unit, has been recognized ... Computerworld,s 2008 Premier 100 honors the 100 ... and motivating employees; envisioning,innovative solutions to business challenges; ...
... 7 Barc, the leader in the $1.8 billion,African-American ... of its new travel size for its market leading ... product is now available,in a convenient 1.7 oz bottle ... reduces irritation and ingrown hairs due to shaving,preventing new ...
... cells and cancer stem cells reveals that the cancer ... of development. The research, published by Cell Press in ... understanding of glioma pathophysiology and provides new directions for ... types of tumors. , Tumor-initiating cells with stem like ...
... COLUMBUS , Ohio New research suggests that at any ... (EMTs) and paramedics in the United States miss work because ... , A study examining how common these injuries are and ... professionals also suggests that in one year, an estimated 8.1 ...
... less food had same effect on weight at age 2, study ... toddlers consume, either by trying to get them to eat less ... weight by the age of 2, new British research suggests. , ... always in the best interest of a young child, according to ...
Cached Medicine News:Health News:3M Donates Two Full Paint Schemes to American Red Cross for the 2008 NASCAR Sprint Cup Season 2Health News:3M Donates Two Full Paint Schemes to American Red Cross for the 2008 NASCAR Sprint Cup Season 3Health News:WellPoint Executive Mark Boxer Recognized as One of Computerworld's 2008 Premier 100 IT Leaders 2Health News:WellPoint Executive Mark Boxer Recognized as One of Computerworld's 2008 Premier 100 IT Leaders 3Health News:Forever young: Differentiation blocked in tumor stem cells 2Health News:Emergency responders at high risk to miss work because of injuries 2Health News:Emergency responders at high risk to miss work because of injuries 3Health News:Parental Control of Eating Leads to Lighter Toddlers 2Health News:Parental Control of Eating Leads to Lighter Toddlers 3
(Date:6/30/2015)... LONDON , June 30, 2015 ... Street issued a survey to Rosacea sufferers as part of ... what treatments Rosacea sufferers found effective for their Rosacea. The ... age, and comprised 47% men and 53% women. ... of survey participants did not consider or attempt to visit ...
(Date:6/30/2015)... June 30, 2015 First Choice Wellness Care ... Astanza Duality and is the only clinic in the ... tattoo removal treatments. The practice has recently expanded their ... brand to showcase their focus in the procedure. They ... results, faster ink clearance, and superior service. ...
(Date:6/30/2015)... June 30, 2015  Avanir Pharmaceuticals, Inc. today ... showing that treatment with NUEDEXTA ® was ... of pseudobulbar affect (PBA) in patients with traumatic ... distressing condition characterized by sudden and uncontrollable outbursts ... diseases or brain injury. PRISM II is a ...
Breaking Medicine Technology:84% of Rosacea Sufferers Say NHS Treatments Were "Ineffective" New Survey Reveals 284% of Rosacea Sufferers Say NHS Treatments Were "Ineffective" New Survey Reveals 3First Choice Wellness Care Becomes Tallahassee Leader In Tattoo Removal With Astanza Duality 2First Choice Wellness Care Becomes Tallahassee Leader In Tattoo Removal With Astanza Duality 3Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 2Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 3Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 4Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 5Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 6Avanir Pharmaceuticals Announces Positive Top-line Results from Stroke and TBI Cohorts of PRISM II Study 7
... Top-line Data Expected in August -, EXTON, ... today the completion of the pivotal efficacy portion ... Isolagen,Therapy(TM) for the treatment of nasolabial folds, or ... the primary efficacy follow-up visit,and collation of this ...
... ... Professionals, VOORHEES, N.J., July 1 ... a wide spectrum of,severity, ranging from mild diarrhea to pseudomembranous colitis ... who develop an initial,case of CDI.(1) These patients are at increased ...
Cached Medicine Technology:Isolagen Completes Pivotal Efficacy Portion of Phase III Studies of Isolagen Therapy(TM) for Wrinkles 2Isolagen Completes Pivotal Efficacy Portion of Phase III Studies of Isolagen Therapy(TM) for Wrinkles 3Current Concepts in Clostridium difficile Infection: A Focus on Recurrent Disease 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: