Navigation Links
Drug Combo Helps Fight Marfan Syndrome
Date:10/2/2007

Inherited condition can lead to sudden cardiac death

TUESDAY, Oct. 2 (HealthDay News) -- Treatment with the heart drug perindopril, along with a beta blocker, may help reduce certain cardiac complications of the hereditary disorder Marfan syndrome, research shows.

Marfan syndrome, which principally affects connective tissues, is often characterized by excessive bone elongation and joint flexibility, and eye and cardiovascular system abnormalities. Progressive dilation and rupture of a major blood vessel, the aorta, are the most serious complications and the most common cause of premature death in people with the disorder, according to background information in the study.

Beta blockers are the current standard treatment for Marfan syndrome, but may not be as effective in treating aortic wall degeneration as other therapies. Previous research has found that ACE inhibitors such as perindopril help reduce arterial stiffness.

Reporting in the Oct. 3 issue of the Journal of the American Medical Association, Australian researchers at the Baker Heart Research Institute examined the effectiveness of perindopril in adult Marfan syndrome patients receiving standard beta-blocker therapy. Ten patients received 8 milligrams/day of perindopril while seven others received a placebo for 24 weeks.

"The major novel finding of our study was that perindopril therapy for 24 weeks reduced aortic diameters relative to placebo in both systole (the contraction of the chambers of the heart) and diastole (the expanding of the chambers of the heart) in patients with Marfan syndrome taking standard beta-blocker therapy," the study authors wrote.

"In systole, perindopril reduced the progression of aortic dilatation observed in the placebo group. However, in diastole, perindoperil actually reduced aortic diameters below baseline levels," they noted.

The researchers recommended a larger, longer-term clinical trial.


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Drug Combo Works Better for children with ADHD, Tics
2. Scanning Combo Helps Detect Lung Cancer
3. Relief From Asthma With New Combo Therapy
4. Calcium-Vitamin D Combo For Reduced Fracture Risk
5. Drug Combo Improves Performance Of Multiple Sclerosis Drug
6. Alcohol-illusion: Alcohol and Energy Drinks Combo, Maintains Sobriety?
7. HER-2 Positive Breast Cancer Patients May Benefit With a Combo Drug Strategy
8. The Combo Treatment Is Effective to Treat Type 1 Diabetes in Mice
9. Doomed Duo: Obesity and Type 2 Diabetes Combo, Can Nip Life in the Bud
10. Arimidex-Herceptin Combo Therapy For Breast Cancer-Clinical Trial Findings
11. Fuzeon and MK-0518 Combo Holds Promise For HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... ... options, Blue Cross and Blue Shield of Minnesota (Blue Cross) has announced Doctor ... , Based in San Francisco, Doctor On Demand provides immediate access to Board ...
(Date:9/1/2015)... ... 2015 , ... Virginia entrepreneur Marcella Ellis, CEO and founder ... firm’s success in the hair care and distribution industry through her combination of ... be providing “Look and learn” live demonstrations, as well as promoting her new ...
(Date:9/1/2015)... Melbourne, Florida (PRWEB) , ... ... ... Association of Professional Background Screeners (NAPBS®) has announced that Edge Information ... audit conducted by the Background Screening Credentialing Council (BSCC). , “Achieving ...
(Date:9/1/2015)... Winston-Salem, NC (PRWEB) , ... September 01, 2015 , ... ... (Science, Technology, Engineering and Math) disciplines since its inception more than 35 years ago. ... and high-school students and their teachers - and, not just those intent on pursuing ...
(Date:9/1/2015)... ... 2015 , ... Royal River Natural Foods, a locally-owned independent natural health store ... 19 years and found that, among those who had a stroke, people who used ... part of the September 2015 issue of “Natural Insights for Well Being,” which Royal ...
Breaking Medicine News(10 mins):Health News:Blue Cross and Blue Shield of Minnesota names Doctor On Demand as preferred telehealth destination 2Health News:Blue Cross and Blue Shield of Minnesota names Doctor On Demand as preferred telehealth destination 3Health News:Beauty Entrepreneur creates hair extension smart machine and mobile app inspired by UBER technology 2Health News:Edge Information Management Granted Continued NAPBS Accreditation 2Health News:Edge Information Management Granted Continued NAPBS Accreditation 3Health News:Inmar Announces Program to Fuel Student Passion for STEM – with an Unconventional Twist 2Health News:New Study Finds Multivitamins Extend Life After Stroke, Retailer Reports 2
... ... ... Noni International (TNI) announced the introduction of two new bioactive beverages in grape and ... loaded with iridoids and other bioactive compounds that support the immune system, neutralize ...
... ... Children,s Advancement Society , ... Sydney, New South Wales (PRWEB) November 29, 2009 -- Australia Souvenir Gift Shop ... Australian souvenirs online to the ACAS (Aboriginal Children,s Advancement Society), a New South Wales ...
... ... reports of severe tissue and bone damage , ... (PRWEB) March 17, 2010 -- According to a recent story in the New York ... of metal on metal artificial hips. New York personal injury attorney David Perecman comments ...
... ... powerful effect. Now it,s proven by Dr. Emoto. In Japan, Dr. Masaru Emoto photographed water ... Emoto could see that the water was miraculously changed to a beautiful snowflake effect. , ... Los Angeles, CA (PRWEB) March 17, 2010 -- ...
... ) announced today that Robert Myers , the company,s President, will present at the Barclays Capital 2010 Global Healthcare Conference on Wednesday, March 24, 2010 at ... ... ... ...
... , WASHINGTON , March 16 A ... human origins opens March 17 at the Smithsonian,s ... research by Smithsonian scientists, the David H. Koch (pronounced "coke") ... a special preview from noon to 3 p.m. Wednesday, ...
Cached Medicine News:Health News:Tahitian Noni Family Released in Grape and Mango Passionfruit 2Health News:Australia Souvenir Gift Shop Donates 10% Of Profits To Help Aboriginal Children 2Health News:Australia Souvenir Gift Shop Donates 10% Of Profits To Help Aboriginal Children 3Health News:New York Personal Injury Attorney David Perecman Comments On Dangers Of ‘Metal On Metal' Hip Implants 2Health News:The Power of James Bond Symbols Proven by Dr. Emoto 2Health News:The Power of James Bond Symbols Proven by Dr. Emoto 3Health News:Jazz Pharmaceuticals to Present at the Barclays Capital 2010 Global Healthcare Conference 2Health News:New Exhibition Hall Devoted to Human Origins Opens at National Museum of Natural History 2Health News:New Exhibition Hall Devoted to Human Origins Opens at National Museum of Natural History 3Health News:New Exhibition Hall Devoted to Human Origins Opens at National Museum of Natural History 4Health News:New Exhibition Hall Devoted to Human Origins Opens at National Museum of Natural History 5Health News:New Exhibition Hall Devoted to Human Origins Opens at National Museum of Natural History 6
(Date:9/1/2015)... --NOWDiagnostics Inc., based in Springdale, Ark. , ... Canada , a move that brings the company ... have greater access to information concerning their health. ... blood-based rapid tests that allow health care providers to ... ailments and diseases. ZBx Corporation, a Toronto ...
(Date:9/1/2015)... , Sept. 1, 2015 Konica Minolta ... Computed Radiography (CR) system, designed to deliver enterprise level ... utilizing the same Control Station as the Konica Minolta ... with an upgrade path from CR to DR. The ... to help improve workflow with unparalleled reliability and high ...
(Date:9/1/2015)... VEGAS , Sept. 1, 2015  Dr. ... DigiPath Labs , the cannabis testing subsidiary of DigiPath, ... Patients Group about the lack of consistency in ... the online resource for medical cannabis information, she explained ... patients because their lack of uniform requirements makes standardization ...
Breaking Medicine Technology:NOWDiagnostics Inc. Acquires Canada's ZBx Corporation 2NOWDiagnostics Inc. Acquires Canada's ZBx Corporation 3Konica Minolta Launches New CR System with Low-Cost Upgrade Path to DR 2DigiPath Labs CSO Dr. Cindy Orser Calls for Uniform Standards for Cannabis Safety Testing 2DigiPath Labs CSO Dr. Cindy Orser Calls for Uniform Standards for Cannabis Safety Testing 3
... the ADA,s Annual Scientific Sessions, SAN FRANCISCO, ... of the dose-finding study for its new,injectable diabetes ... American Diabetes Association,s (ADA) 68th Annual Scientific Sessions,meeting ... that AVE0010 was well tolerated and significantly,improved glycemic ...
... California, June 6 , - "ADVANCE Results ... the world,s largest ever study of diabetes treatments,show ... release,gliclazide and other drugs as required, protects patients ... treatment reduces,the risk of kidney disease by one-fifth. ...
Cached Medicine Technology:New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study 2New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study 3New Diabetes Compound AVE0010 Showed Clear Dose Response Results With Once-A-Day Injection in Phase IIb Study 4The Largest Ever Study of Diabetes Shows Intensive Glucose Control Reduces Serious Complications 2
... ergonomic chairs with concave seats ... support • Select options like ... and glides. • BTT/1P chairs ... environments: industry, education, laboratory, clean ...
... with concave seats and standard-sized ... Select options like seats, backrests, ... • BTT/1P chairs are recommended ... education, laboratory, clean room, static ...
... chairs with concave seats and large ... options like seats, backrests, armrests, and ... BE Series for top performance in ... education, laboratory, clean room, static control, ...
... ergonomic chairs with concave seats and ... Select options like seats, backrests, armrests, ... the BE Series for top performance ... industry, education, laboratory, clean room, static ...
Medicine Products: