Navigation Links
Drug Combo Helps Fight Marfan Syndrome
Date:10/2/2007

Inherited condition can lead to sudden cardiac death

TUESDAY, Oct. 2 (HealthDay News) -- Treatment with the heart drug perindopril, along with a beta blocker, may help reduce certain cardiac complications of the hereditary disorder Marfan syndrome, research shows.

Marfan syndrome, which principally affects connective tissues, is often characterized by excessive bone elongation and joint flexibility, and eye and cardiovascular system abnormalities. Progressive dilation and rupture of a major blood vessel, the aorta, are the most serious complications and the most common cause of premature death in people with the disorder, according to background information in the study.

Beta blockers are the current standard treatment for Marfan syndrome, but may not be as effective in treating aortic wall degeneration as other therapies. Previous research has found that ACE inhibitors such as perindopril help reduce arterial stiffness.

Reporting in the Oct. 3 issue of the Journal of the American Medical Association, Australian researchers at the Baker Heart Research Institute examined the effectiveness of perindopril in adult Marfan syndrome patients receiving standard beta-blocker therapy. Ten patients received 8 milligrams/day of perindopril while seven others received a placebo for 24 weeks.

"The major novel finding of our study was that perindopril therapy for 24 weeks reduced aortic diameters relative to placebo in both systole (the contraction of the chambers of the heart) and diastole (the expanding of the chambers of the heart) in patients with Marfan syndrome taking standard beta-blocker therapy," the study authors wrote.

"In systole, perindopril reduced the progression of aortic dilatation observed in the placebo group. However, in diastole, perindoperil actually reduced aortic diameters below baseline levels," they noted.

The researchers recommended a larger, longer-term clinical trial.


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Drug Combo Works Better for children with ADHD, Tics
2. Scanning Combo Helps Detect Lung Cancer
3. Relief From Asthma With New Combo Therapy
4. Calcium-Vitamin D Combo For Reduced Fracture Risk
5. Drug Combo Improves Performance Of Multiple Sclerosis Drug
6. Alcohol-illusion: Alcohol and Energy Drinks Combo, Maintains Sobriety?
7. HER-2 Positive Breast Cancer Patients May Benefit With a Combo Drug Strategy
8. The Combo Treatment Is Effective to Treat Type 1 Diabetes in Mice
9. Doomed Duo: Obesity and Type 2 Diabetes Combo, Can Nip Life in the Bud
10. Arimidex-Herceptin Combo Therapy For Breast Cancer-Clinical Trial Findings
11. Fuzeon and MK-0518 Combo Holds Promise For HIV
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... December 17, 2014 A group of 127 ... Longevity, today, in reaction to a recent statement by the ... brain training and derogated the efficacy of all brain exercises. ... with the parts of the center’s statement critical of brain ... center had also overstated its case, in a document it ...
(Date:12/17/2014)... No matter how far modern medicine ... the head louse parasite—a common childhood malady and a ... between six and twelve million individuals will suffer an ... treatment company comes to the rescue, providing an all-natural ... its track record of customer service, and effectiveness in ...
(Date:12/17/2014)... December 17, 2014 Project Veritas is ... brought videos of MIT economist and Obamacare architect Jonathan ... James O’Keefe conducted the interview, which is being distributed ... there was intentional mislabeling in the Affordable Care Act ... bill: A two-hundred-and-fifty billion dollar per year tax grab. ...
(Date:12/17/2014)... Alan Mozes HealthDay Reporter , ... of infectious diseases, one worrisome phenomenon is when an illness ... process -- known as zoonosis -- is not uncommon and ... that an animal-borne disease might make inroads into the human ... development -- and the culprits in this case were guinea ...
(Date:12/17/2014)... -- Poor students get more fruits and vegetables at school ... But, the opposite is true for students from wealthier families. ... school may give a healthy boost to poor students, diets, ... family income level, students all ate a similar amount of ... study was published recently in the journal Preventive Medicine ...
Breaking Medicine News(10 mins):Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 2Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 3Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 4Health News:Lice Troopers Announces New Lice Treatment Clinic in Coral Gables to Service Key Biscayne, Coconut Grove, Kendall, Brickell & South Miami 2Health News:Project Veritas: James O’Keefe Interviews the Man Who Discovered Jonathan Gruber Videos 2Health News:Guinea Pigs Can Be Source of Serious Strep Infection 2Health News:Guinea Pigs Can Be Source of Serious Strep Infection 3Health News:Poor Students Eat Healthier Foods at School, Study Finds 2
... already revolutionized the way people around the world communicate and ... are about to do the same thing for medicine. ... engineering professor Aydogan Ozcan, a prototype cell phone has been ... and malaria patients, as well as testing water quality in ...
... the animals from smoke,s harmful effects, researchers say , , ... mice, scientists have shown that a new drug may ... cigarettes. , The finding holds out hope for patients ... progressive lung disease involving both emphysema and chronic obstructive ...
... of kids, meals served at fast-food restaurants met federal ... nutrient quality of such meals in a major U.S. ... food science and human nutrition researcher with the Michigan ... and pediatrician Jason Mendoza from Baylor College of Medicine ...
... Misled into Purchasing Brand Name Product Identical to Less Expensive Solution ... ... CA (PRWEB) December 22, 2008 -- The Schmidt Firm, LLP in ... Inc. ("AMO") was named as the defendant in a consumer fraud ...
... Scientists at the U.S. Department of Energy,s (DOE) Brookhaven ... third subtype of botulinum neurotoxin a deadly toxin ... and is also used in cosmetic and therapeutic applications ... The detailed structure, published online December 22, 2008, by ...
... normally help protect lungs by removing inhaled toxins, study ... may face an increased risk of lung cancer if ... potent of cigarette smoke carcinogens, a new study says. ... help protect the lungs by removing inhaled toxins. Specifically, ...
Cached Medicine News:Health News:Cell phones using lens-free imaging promise to improve health monitoring 2Health News:Drug Shields Mice From Emphysema 2Health News:Nutritious fast-food kids' meals are scarce, researchers find 2Health News:Californian Files Contact Lens Solution False Advertising Class Action Against Advanced Medical Optics, Announces the Schmidt Firm, LLP 2Health News:Californian Files Contact Lens Solution False Advertising Class Action Against Advanced Medical Optics, Announces the Schmidt Firm, LLP 3Health News:Scientists reveal structure of new botulism nerve toxin subtype 2Health News:Scientists reveal structure of new botulism nerve toxin subtype 3
(Date:12/19/2014)... , Dec. 18, 2014  RESMED INC. (NYSE: ... second quarter of fiscal year 2015 results on Thursday, January ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
(Date:12/19/2014)... separating membrane market has witnessed robust development with the ... as a later starter. In 2012, the size of ... billion, with the proportion worldwide soaring to 16.3%. It is ... will continue its growth rate by around 20% in the ... to roughly RMB25 billion. An integrated membrane industrial ...
(Date:12/17/2014)... N.Y. , Dec. 17, 2014  Northstar ... The Depository Trust Company (DTC) has made their ... Deposit Chill on the Company,s stock effective December ... Northstar,s common stock for depository and book entry ... the Company is now once again fully "DTC ...
Breaking Medicine Technology:ResMed To Announce Second Quarter 2015 Results 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3
Features a twist-on backswitch, with a diffused, cobalt blue light beam....
Heavy duty, all purpose illuminator available in black only. Unique Clip Switch automatically turns off when returned to pocket. Pre-focused lens tip Heine XHL Halogen bulb for bright, concentrated l...
... vision test that's automatic, ... seconds. Welch Allyn created ... accurate vision test that ... of refractive error, the ...
Portable video magnifier. This powerful new portable unit offers maximum flexibility and control. Includes a wider range of magnification settings, adjustable brightness, and even a tilted screen to ...
Medicine Products: