Navigation Links
Drug Combo Boosts Multiple Myeloma Survival
Date:11/21/2007

A thalidomide derivative plus dexamethasone improved outcomes, studies found

WEDNESDAY, Nov. 21 (HealthDay News) -- A combination drug regimen that includes a derivative of thalidomide extended survival, as well as the time it took for the disease to reappear, in patients with multiple myeloma.

The combination of Revlimid (lenalidomide) and dexamethasone was given U.S. Food and Drug Administration regulatory approval in June of 2006 for multiple myeloma patients who had already failed one treatment.

Now, two papers, appearing in the Nov. 22 issue of the New England Journal of Medicine, mark the final publications of the study that paved the way for that approval, said Hildy Dillon, vice president of patient services disease programs at the Leukemia & Lymphoma Society in White Plains, N.Y.

"People who got [the combination regimen] had three times the likelihood of responding," added Dr. Donna M. Weber, lead author of the North American segment of the study and associate professor of medicine at M.D. Anderson Cancer Center in Houston. "Overall survival showed a nine-month improvement from 20.2 to 29.6 months," she said.

Multiple myeloma is a cancer of the blood's plasma cells that causes almost 11,000 deaths each year in the United States. Experts say the new findings -- along with the recent FDA approval of the drug combo -- should greatly broaden the treatment landscape for multiple myeloma, which historically has been a difficult disease to treat.

Revlimid is a derivative of thalidomide, with alterations in its chemistry that give it more potency with fewer side effects, experts explained.

Thalidomide first appeared in Europe in the 1950s to treat morning sickness in pregnant women. Between 1956 and 1962, however, some 10,000 children were born with severe birth defects as a result of their mother having taking the drug.

But more recently, the drug has show
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Radiation and drug combo helps boost efficacy of lung cancer treatment
2. Aerobic, Weight Training Combo Best Against Diabetes
3. New antibiotic drug combo to speed up treatment of tuberculosis
4. Drug Combo Helps Fight Marfan Syndrome
5. Drug Combo Blocks Pain Without Impairing Movement
6. Two-Drug Combo Fights Brain Tumors
7. CPR, Defibrillator Combo Boosts Cardiac Incident Survival
8. New treatment boosts muscle function in myasthenia gravis
9. Heavy Drinking Boosts Stroke Risk for Chinese Men
10. Traffic Fumes Plus Genes Boosts Kids Asthma Risk
11. Heart Attack Boosts Diabetes Risk
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug Combo Boosts Multiple Myeloma Survival
(Date:9/1/2014)... Garden City, NY (PRWEB) September 02, 2014 ... B. Brinkley, Office Manager at Gibson Orthopedics ... Professional Woman of the Year. Ms. Brinkley is ... healthcare administration. As the largest, most-recognized networking organization ... industry and profession, the National Association of Professional ...
(Date:9/1/2014)... is broadly believed to be nonaddictive, a ... that 40 percent of cannabis-using adolescents receiving outpatient ... of withdrawal, which are considered a hallmark of ... more likely to meet criteria for severe substance ... or absence of withdrawal did not appear to ...
(Date:9/1/2014)... Phoenix, AZ (PRWEB) September 01, 2014 ... Wellness conference, the American Sleep and Breathing Academy ... Wellness conference: A Conference for Healthcare Professionals. The event ... Scottsdale, Arizona on April 10th and 11th. This years’ ... experience delivered by the ASBA. , In recent ...
(Date:9/1/2014)... Reinberg HealthDay Reporter ... head-to-head comparison, an experimental drug was more effective than ... failure patients. According to the study authors, the ... of the new drug, dubbed LCZ696. In ... medication, enalapril (Vasotec), either died or were hospitalized due ...
(Date:9/1/2014)... An operating theatre or operating room ... surgical operations. An operating room comprises a myriad of ... room lights, imaging displays as well as integration systems ... Market Research, a U.S.-based market research firm, the operating ... billion by 2019. , According to this report, ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Announces Laura Brinkley, Manager, Gibson Orthopedics Pain Treatment & Cardiology Clinic, a 2014 Professional Woman of the Year 2Health News:Cannabis withdrawal symptoms common among adolescents treated for substance use disorder 2Health News:Cannabis withdrawal symptoms common among adolescents treated for substance use disorder 3Health News:Pro Player Health Alliance Confirms Big Name Speakers at 2015 American Sleep and Breathing Academy Conference 2Health News:Pro Player Health Alliance Confirms Big Name Speakers at 2015 American Sleep and Breathing Academy Conference 3Health News:Pro Player Health Alliance Confirms Big Name Speakers at 2015 American Sleep and Breathing Academy Conference 4Health News:Drug Gives 'New Hope' Against Heart Failure, Expert Says 2Health News:Drug Gives 'New Hope' Against Heart Failure, Expert Says 3Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 2Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 3
... to Take Medicines Safely, WASHINGTON, July 29 ... and Drug Administration to issue a guidance for ... receive their,prescription drugs. In a petition filed on ... organizations including the National,Association of Chain Drug Stores, ...
... AMERICANS will be diagnosed at some point in their lives ... One of the professions at the frontlines in the battle ... power and innovation of physics to study and solve the ... new imaging technologies, such as dedicated breast CT scans, and ...
... mark on the brain, by changing patterns of brain ... attention. For one in six Americans who have overactive ... frequent urges to urinate, such mind-body connections may be ... tend to focus on just one organ, but here ...
... and high thyrotropin levels associated with disease incidence, but ... News) -- High or low levels of the hormone ... Alzheimer,s disease in women. Thyrotropin affects thyroid gland function ... 1979, researchers at Beth Israel Deaconess Medical Center and ...
... to affect memory, concentration, study finds, , , TUESDAY, July ... to keep prostate cancer at bay may experience memory ... , Testosterone is thought to help spur prostate cancer. ... years to treat the disease. By reducing the level ...
... American Society for Biochemistry and Molecular Biology (ASBMB) has ... 2009 Howard K. Schachman Public Service Award, the society,s ... recognized for their outstanding commitment in supporting public health ... United States but around the world, through the Bill ...
Cached Medicine News:Health News:Consumer and Healthcare Groups Call for Clear, Concise Single Document From Pharmacy 2Health News:Cancer research highlights 2Health News:Cancer research highlights 3Health News:Cancer research highlights 4Health News:Cancer research highlights 5Health News:Cancer research highlights 6Health News:Cancer research highlights 7Health News:Cancer research highlights 8Health News:Cancer research highlights 9Health News:Cancer research highlights 10Health News:Cancer research highlights 11Health News:Cancer research highlights 12Health News:Cancer research highlights 13Health News:Cancer research highlights 14Health News:Cancer research highlights 15Health News:Cancer research highlights 16Health News:Cancer research highlights 17Health News:Findings on bladder-brain link may point to better treatments for problems in sleep, attention 2Health News:Thyroid Hormone May Boost Women's Alzheimer's Risk 2Health News:Prostate Cancer Treatment Could Impair Men's Thinking 2Health News:Prostate Cancer Treatment Could Impair Men's Thinking 3Health News:ASBMB honors Bill and Melinda Gates with Schachman Award 2
(Date:8/29/2014)... British Columbia and MENLO PARK, ... DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) ("DelMar" "the ... fiscal year-end financial statements.  The Company recently changed its ... facilitate an application to list its common stock on ... DelMar,s financial statements as filed with the ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Global Orthopedic Soft Tissue Repair Devices Market 2014-2018" ... tissues are the mass of cells that connect, support, ... soft tissues such as tendons, ligaments, cartilage, fascia, and ... degeneration of these tissues with age result in wear ...
(Date:8/29/2014)... , Aug. 29, 2014 ... PHG AEX: PHIA) ... European Society of Cardiology (ESC) Congress ... highlighting the full range of its cardiology solutions serving clinicians ... from prevention and diagnosis, to ...
Breaking Medicine Technology:DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 2Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 2Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 4Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 5
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: