Navigation Links
Drops of Fatty Acid Curb Symptoms of Dry Eye Syndrome

Mouse study suggests new treatment options without unwanted side effects

WEDNESDAY, Feb. 13 (HealthDay News) -- Eye drops containing alpha-linolenic acid (ALA) significantly reduced symptoms of dry eye syndrome in mice, a new study says.

ALA is an omega-3 fatty acid that's not made by the body and has to be obtained through diet. Dry eye, which affects about 10 million people in the United States, causes symptoms such as stinging, burning, irritation or a feeling of scratchiness. It can lead to problems with day-to-day activities such as driving and reading.

Currently, treatment options are limited in terms of effectiveness and undesirable side effects, according to background information in the study, published in the February issue of the journal Archives of Ophthalmology.

Dr. Reza Dana, a Harvard Medical School professor and Cornea Service Director at the Massachusetts Eye and Ear Infirmary, and colleagues at the Schepens Eye Research Institute tested three formulations of fatty acids: 0.2 percent ALA; 0.2 percent linoleic acid (an omega-6 fatty acid); and 0.01 percent ALA combined with 0.1 percent linoleic acid.

Some mice received once-a-day treatment with these eye drops, while other mice did not receive any eye drops. The eyes of mice treated with ALA showed a significant reversal in epithelial damage to the cornea, which is the transparent dome that covers the pupil.

"The current study for the first time demonstrates the benefit of topical application of a particular fatty acid in treating the signs of dry eye syndrome at both the molecular and cellular levels," Dana noted.

"Using topical formulations of fatty acids to treat dry eye would allow for more flexibility for treatment, including lessening side effects that patients can experience from oral intake of fatty acids. Clinical studies with topical fatty acids are being planned, which, if successful, could alter the method by which this common condition is treated," Dana said.

The study received funding from Johnson & Johnson Vision Care Inc.

More information

The U.S. National Library of Medicine has more about dry eye syndrome.

-- Robert Preidt

SOURCE: Harvard Medical School, news release, Feb. 11, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New buffer resists pH change, even as temperature drops
2. Over-the-counter eardrops may cause hearing loss or damage
3. Over-the-counter eardrops may cause hearing loss or damage
4. Diet Change Can Curb Fatty Liver Disease
5. Attenuation of NASH by stimulation of free fatty acid metabolism
6. New treatment effective in counteracting cocaine-induced symptoms
7. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
8. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
9. New study: Pine bark reduces perimenopausal symptoms
10. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
11. Clean to Ease Allergy and Asthma Symptoms
Post Your Comments:
Related Image:
Drops of Fatty Acid Curb Symptoms of Dry Eye Syndrome
(Date:11/25/2015)... ... November 25, 2015 , ... “While riding the bus, I ... Bronx, N.Y. “I thought there had to be a convenient and comfortable way to ... The PROTECTOR enables disabled individuals to safely travel during cold or inclement weather. In ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible for advancing care ... disease. The Periwinkle Pioneers, nominated by the public, will receive special recognition throughout ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... philanthropic seniors, is resulting in a way for homeless people to have a ... have launched a new initiative whereby they are repurposing plastic bags into sleeping ...
(Date:11/25/2015)... ... November 25, 2015 , ... Since its launch in 2012, ... adult stem cell therapies to patients with chronic degenerative medical conditions. Now, the ... Registered Trademark (RTM). , Organizations are required to hold a registered trademark in ...
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software ... software creates an agreement between the practice owner and the patient that automatically ... notification, and projections. Click here to learn more. , ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... FRANCISCO , Nov. 24, 2015  Thanks to ... Dignity Health St. Mary,s Medical Center,s Sister Diane Grassilli ... breast imaging capabilities in San Francisco ... an anonymous friend, stepped forward with a gift of ... for Breast Digital Mammography with Tomosynthesis and Whole Breast ...
(Date:11/24/2015)... Colo. , Nov. 24, 2015  Array ... that its Chief Executive Officer, Ron Squarer ... Healthcare Conference in New York.  The public is ... webcast on the Array BioPharma website.Event:Piper Jaffray Annual ... , Wednesday, December 2, 2015Time:1:30 p.m. Eastern Time ...
(Date:11/24/2015)... HOUSTON, TX and VANCOUVER, Nov. 24, 2015 /PRNewswire/ ... EPI; NASDAQ: EPIX ) announced today that the ... clinical study of EPI-506 as a treatment for metastatic ... States and Canada.  --> ... --> In the Phase 1/2 clinical trial, ...
Breaking Medicine Technology: