Navigation Links
Drinking Patterns Affect Heart Health, Mouse Study Finds
Date:9/14/2011

WEDNESDAY, Sept. 14 (HealthDay News) -- How often you consume alcohol may be more important than how much you consume in determining the risk of heart disease, new research in mice shows.

Researchers have found that binge drinking, defined as having seven drinks a day for two days in a week, may lead to weight gain and an increased risk for atherosclerosis or "hardening of the arteries" caused by fatty deposits on the walls of the arteries.

But the researchers from the University of Rochester Medical Center in New York found the opposite holds true for those who drink moderately on a regular basis. The study, performed in mice, revealed that drinking about two drinks every day may actually decrease the risk for heart disease.

"People need to consider not only how much alcohol they drink, but the way in which they are drinking it," lead study author John Cullen, research associate professor in the university's department of surgery, said in a university news release. "Research shows that people have yet to be convinced of the dangers of binge drinking to their health; we're hoping our work changes that."

In conducting the study, the researchers divided mice into three groups, including:

  • A "daily-moderate" group, which was fed the ethanol equivalent of two drinks a day, seven days a week.
  • A "weekend-binge" group, which was fed about seven drinks on two days of the week.
  • A "control" group, which was fed a non-alcoholic cornstarch mix.

Additionally, all of the mice were given a high-fat diet -- simulating a typical "Western" diet with fried foods -- to increase the development of atherosclerosis.

The investigators found that levels of low-density lipoprotein (LDL) cholesterol -- known as "bad" cholesterol -- dropped 40 percent in the daily-moderate drinking mice, but jumped 20 percent in the weekend-binge-drinking mice, compared to the control group. The researchers noted that previous studies have shown a 10 percent increase in LDL causes a 20 percent increase in atherosclerosis risk.

The amount of plaque, as well as the number of immune cells that cause inflammation and clogged arteries, decreased in the daily-moderate mice. The opposite was true for the binge-drinking mice, the investigators found.

Meanwhile, despite similar starting weights and diets, the binge-drinking mice gained more than three times as much weight as the moderate mice and about twice as much weight as the control mice.

"Because obesity is also a risk factor for disease, binge drinking may have a strong negative impact on cardiovascular health," Lucy Liaw, research committee chair of the American Heart Association's Founders Affiliate, noted in the news release.

Based on the study's findings, the researchers suggested that health care professionals should ask how their patients drink when considering their risk for atherosclerosis.

"This evidence is very interesting because it supports a pattern of drinking that is emerging in clinical studies as both safe and seemingly most protective against heart disease -- frequent consumption of limited amounts of alcohol. This certainly backs up widespread clinical guidelines that limit drinking to one drink daily for non-pregnant women and two drinks daily for men," Dr. Kenneth Mukamal, associate professor of medicine at Harvard Medical School, stated in the news release.

The study authors pointed out that exactly how moderate amounts of alcohol benefit heart health -- or how heavy drinking hurts it -- remains unknown. They added, however, that the nearly 15 percent of Americans who binge drink (as estimated by the U.S. Centers for Disease Control and Prevention) should be aware of the risks to their health.

More information

The American Heart Association provides more information on alcohol and heart disease.

-- Mary Elizabeth Dallas

SOURCE: University of Rochester Medical Center, news release, Sept. 7, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Drinking Milk While Pregnant May Lower Kids MS Risk
2. Coffee Drinking and Caffeine Associated With Reduced Risk of Hospitalization for Heart Rhythm Disturbances
3. Anti-Drinking Ads That Engender Guilt May Not Work
4. Light Drinking Might Help Keep Women Slim
5. Mother of Binge Drinking Victim Urges Students and Parents to Discuss Signs of Alcohol Poisoning, Emphasize Peer Responsibility Prior to Spring Break
6. Obesity, Drinking a Double Threat to the Liver
7. Progress In Access To Safe Drinking-Water; Sanitation Needs Greater Efforts
8. Light Drinking Good for the Heart
9. Binge drinking doesnt affect next-day student test-taking
10. Underage Drinking Soars in U.S.
11. Heavy Daily Drinking Linked to Worse Health
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drinking Patterns Affect Heart Health, Mouse Study Finds
(Date:12/2/2016)... ... December 02, 2016 , ... U.S. Surgeon General, Dr. Vivek Murthy, ... Murthy explains how he was inspired to practice medicine at an early age by ... about more than making diagnoses and prescribing medicine,” he states. “It is about building ...
(Date:12/2/2016)... York, NY (PRWEB) , ... December 02, 2016 , ... ... high school and while 84 percent of parents report speaking with their child about ... pornography and sexually transmitted diseases. , Mediaplanet is proud to announce the launch of ...
(Date:12/2/2016)... ... December 02, 2016 , ... Universal Medical Systems, ... and the first company to offer robotic imaging to veterinary medicine is sponsoring ... # 941 for the American Association of Equine Practitioners 62nd Annual Convention from ...
(Date:12/2/2016)... ... December 02, 2016 , ... "Pro3rd Accents Volume 2 is a ... versatile lower third titles with just a few clicks of the mouse," said Christina ... 30 lower third animations. Choose from various styles with accented animations, rigid boxes, simplistic ...
(Date:12/2/2016)... ... December 02, 2016 , ... Date aired: ... of Type 2 Diabetes: The Owner’s Manual, http://realtimepressrelease.com/press-releases-tagged-with/daryl-wein , Sharon ... of Water, Global Climate Change and Your Health radio program syndicated on Voice ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... bioLytical Laboratories, ein Weltführer bei schnellen Tests für Infektionskrankheiten, hat sein ... eingeführt. Continue Reading ... ... , ... ) bioLytical wurde durch die Clinton Health Access ...
(Date:12/2/2016)... Dec. 2, 2016 Boston Scientific Corporation (NYSE: ... to acquire certain manufacturing assets and capabilities of the ... advanced biological tissue business, as well as a 15% ... million in cash. The Neovasc advanced biological tissue business ... Boston Scientific Lotus™ Valve System. * Upon completion ...
(Date:12/2/2016)... Lianluo Smart Limited (Nasdaq: ... develops, markets and sells medical devices and wearable ... and international markets, recently attended the 2016 ... Progress Forum, co-hosted by the Institute of Interventional ... Guangdong Provincial People,s Hospital and Cardiology Department of ...
Breaking Medicine Technology: