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Drexel Scientists Develop Compound to Stop Spread of Metastatic Cancer Cells
Date:7/28/2014

t additional benefit is that the new compounds are not toxic,” adds Salvino. “We’re not talking about chemotherapy. We aim to develop a medication that someone could safely take in combination with their normal standard of care.”

The National Cancer Institute reviewed the discovery and deemed it scientifically meritorious to accept into its highly competitive Experimental Therapeutics Program (NExT), which gives the scientists access to the Institute’s drug discovery, preclinical and clinical development resources up to stage 2 clinical trials. The funding for this project is not yet finalized, but similar programs funded through NExT had budgets of approximately five million dollars.

The trials, which should begin in the next three to five years, will focus on advanced breast cancer patients with evidence of metastatic disease. But both scientists believe their discovery could have implications for other types of cancer as well, particularly prostate cancer.

“This really is a translational scientist’s dream come true,” said Fatatis, who as a medical doctor in addition to a PhD stressed the personal significance of working on something that could be brought from the bench to the clinic with the potential to make a real difference for patients.

Salvino adds, “This is the true definition of scientific collaboration. It’s not one isolated scientist in a lab. This is the result of scientists with different areas of expertise getting together and figuring out how to really make an impact.”

                                             
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