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Draining away brain's toxic protein to stop Alzheimer's
Date:8/13/2007

rvice in the brain, shuttling amyloid-beta out of the brain and into the body. The amyloid plaques that speckle the brains of Alzheimers patients are a hallmark of the disease, and where they come from and how to get rid of them has long been a focus of scientists.

We used to think that Alzheimers disease was a problem with the production of too much amyloid-beta, but its become clear in recent years that the problem is with faulty clearance of amyloid-beta, said Zlokovic, professor of Neurosurgery and Neurology and director of the Frank P. Smith Laboratory for Neuroscience and Neurosurgery Research. We arent really talking about massive amounts of amyloid-beta. Even a small malfunction in the elaborate system that carries it into or out of the brain could lead, over years, to accumulate in amounts that damage the brain.


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Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center
Source:Eurekalert

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