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Dr. Ronald E. Cape to Retire from EntreMed Board of Directors
Date:4/7/2008

nts of the NIH National Library of Medicine.

In announcing his pending retirement, Dr. Cape commented, "I am pleased to have served on the EntreMed Board during its rebuilding period. The Company has promising programs that are making good progress, but I would now like to spend more time with my family and friends. I wish everyone at EntreMed continued progress."

EntreMed Board Chairman, Michael M. Tarnow commented, "Dr. Cape has been a distinguished member of our Board since he joined in 2003. He has been involved in the biotech industry virtually from the beginning, and he has participated actively in its development since those early days. His valuable contributions to the field of biotechnology and his contribution to EntreMed are hallmarks of his leadership and commitment to the industry. We are honored to have had the opportunity to draw from Dr. Cape's vast knowledge and sage advice. While his service will be missed, we wish him all the best in his retirement."

About EntreMed

EntreMed, Inc. is a clinical-stage pharmaceutical company developing therapeutic candidates primarily for the treatment of cancer and inflammation. MKC-1 is currently in multiple Phase 2 clinical trials for cancer. MKC-1 is an oral cell-cycle regulator with activity against the mTOR pathway. ENMD-1198, a novel antimitotic agent, is in a Phase 1 study in advanced cancer patients and ENMD-2076, a selective kinase inhibitor, is expected to begin a Phase 1 study in 2Q08. The Company also has an approved IND application for Panzem(R) in rheumatoid arthritis. EntreMed's goal is to develop and commercialize new compounds based on the Company's expertise in angiogenesis, cell-cycle regulation and inflammation -- processes vital to the treatment of cancer and other diseases, such as rheumatoid arthritis. Additional information about EntreMed is available on the Company's web site at http://www.entremed.com and in var
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