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Dr. Michael Brownlee receives JDRF Rumbough Award for Scientific Excellence
Date:5/19/2008

May 19, 2008 (BRONX, NY) Michael Brownlee, M.D., the Anita and Jack Saltz Professor of Diabetes Research at Albert Einstein College of Medicine of Yeshiva University, has been selected by the Juvenile Diabetes Research Foundation (JDRF) to receive the prestigious David Rumbough Award for Scientific Excellence. The award recognizes researchers for their outstanding achievement and commitment to diabetes research. Actress Dina Merrill established this award in 1974 in honor of her late son, David.

Upon the presentation of the award, Ms. Merrill noted, I am honored to join with you tonight in the presentation of the David Rumbough Award for Scientific Excellence, which was established in honor of my late, beloved son, David. He would have been very pleased to know that research towards a cure is progressing rapidly and improving the lives of so many. Keep up the good work.

Dr. Brownlee is one of the most respected and influential scientists in his field and is noted for his innovative approach to understanding the biochemical basis of diabetic complications. He is internationally recognized for his research including his discovery of a novel molecular pathway linking hyperglycemia to diabetic retinopathy, a complication of the disease.

His propensity for creative exploration has also led to other notable contributions to the field of knowledge in understanding type 1 diabetes and its complications. For example, through his studies, Dr. Brownlee has established that the four seemingly independent biochemical pathways found to contribute to hyperglycemia-induced damage in type 1 diabetes polyol pathway activation, advanced glycation endproduct (AGE) formation, protein kinase C (PKC), and hexosamine pathway activation all arise from a single hyperglycemia-induced process that is initiated by overproduction of toxic free radicals produced by the cells mitochondria. He also has demonstrated that normalizing free-radical levels inh
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Contact: Karen Gardner
kgardner@aecom.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

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