Navigation Links
Doubling Tamiflu Dose for Severe Flu Doesn't Help: Study
Date:5/31/2013

THURSDAY, May 30 (HealthDay News) -- People with a severe case of the flu don't benefit from taking double doses of the antiviral drug Tamiflu, according to a new study conducted in Southeast Asia.

Tamiflu (oseltamivir) stocks could be conserved during pandemics if doctors prescribe only standard doses of this medication, World Health Organization experts suggested.

The study involved 326 patients diagnosed with severe flu at 13 hospitals in Indonesia, Singapore, Thailand and Vietnam between April 2007 and February 2010. Most of the patients were children younger than 15, but some adults also were included.

Health-care workers treated the patients with either a standard dose of Tamiflu (75 milligrams twice daily or the children's equivalent), or a double dose of the medication (150 milligrams twice daily or children's equivalent) over the course of five days.

Patients' virus levels were measured through nose and throat swabs. Researchers then tracked how many patients died, were admitted to the intensive care unit or required the help of a ventilator to breath.

After five days of treatment, there were no differences between the patients on a standard dose of Tamiflu and those given the double dose. Moreover, no differences were seen in death rates or other adverse events, the study found.

The findings were published online May 30 in the journal BMJ.

The study authors concluded that there's no added benefit from a higher dose of Tamiflu to treat severe flu, according to a journal news release.

In an accompanying editorial, Ian Barr and Aeron Hurt from the WHO Collaborating Centre for Reference and Research on Influenza, wrote that a double dose of Tamiflu "is unlikely to significantly improve the clinical outcomes of severe cases of seasonal influenza."

They added that the study's findings "could help to preserve oseltamivir (Tamiflu) stocks during a future pandemic if clinicians were to prescribe only regular rather than double doses." They noted, however, that flu treatment options must be expanded and further research is needed on more effective combinations of drugs.

More information

The U.S. Centers for Disease Control and Prevention has more about flu drugs.

-- Mary Elizabeth Dallas

SOURCE: BMJ, news release, May 30, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Doubling Up on Cold, Flu Remedies May Harm Liver
2. Doubling down against diabetes
3. Doubling down on heart failure: Researchers discover new route to disease, and drugs to match
4. New China Bird Flu May Be Resistant to Tamiflu
5. Spot Shortages of Flu Vaccine, Tamiflu Reported, FDA Head Says
6. Flu Drug Tamiflu OK for Babies Under 1: FDA
7. Release all Tamiflu data as promised, argue researchers
8. Vaginal Mesh Lawsuit Filed by Wright & Schulte LLC on Behalf of Iowa Woman Who Sustained Severe, Permanent Injuries Allegedly Due to Defective Ethicon Bladder Mesh
9. Telcom & Data Introduces Wheelock SAFEPATH® SP40S Emergency Evacuation System, An Effective Office Tool to Protect Employees from Severe Weather Threats
10. Ten Skechers Lawsuits Filed by Wright & Schulte on Behalf of Consumers Who Sustained Severe Tendon Damage Allegedly Due to Wearing Skechers Shape-Ups
11. New Treatment for Severe Asthma Introduced at St. Elizabeth Health Center
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Doubling Tamiflu Dose for Severe Flu Doesn't Help: Study
(Date:8/19/2017)... ... August 19, 2017 , ... Praeclarus Press ... mothers. These illustrations show the diversity of the breastfeeding mothers, using bright ... range of sizes. These illustrations are also available on tote bags, notepads, smartphone ...
(Date:8/18/2017)... ... August 19, 2017 , ... Mr. Noppadon Pakprot, Deputy ... Amazing Thailand Health and Wellness Tourism Showcase 2017 yesterday, which unveiled the latest ... for Tourism Products and Business at TAT said, “Thailand has long been recognized ...
(Date:8/18/2017)... ... August 18, 2017 , ... August ... “Vision & Hearing,” advocating for active, healthy lifestyles and highlighting the importance of ... individuals with hearing impairments and shares the latest innovations in hearing aid technology. ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... ... consulting services and asset protection assistance to communities in North-Central West Virginia, is ... critical services to at-risk boys in the area. , The Chestnut Mountain Ranch ...
(Date:8/18/2017)... ... 2017 , ... The Golseth Agency, a Texas based insurance management and financial ... regional charity campaign organized to provide support to Christina Upchurch and her two children ... and her children returned from out of town to find her husband passed away ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... Aug. 15, 2017   Mostyn Law and Gulf Coast ... Houston, Texas . The Mostyn Law family has ... years. That is why Mostyn Law is partnering with ... to show its appreciation. Blood supplies are running low. ... short of hospital needs in August. That is why the blood ...
(Date:8/15/2017)... N.C. , Aug. 15, 2017  Axium Pharmaceuticals Inc., the creator ... rumored to be in the beginning stages of an IPO. ... on epilepsy medications with the average cost of a prescription epilepsy drug ... ... Another staggering figure is the fact ...
(Date:8/15/2017)... , Aug. 15, 2017  AOTI Inc. announced today that its ... Inc., has recently opened a New York City Office in ... of its unique Topical Wound Oxygen (TWO 2 ) homecare therapy. ... Accreditation Commission for Health Care (ACHC) under the company,s DMEPOS accreditation ... ...
Breaking Medicine Technology: