Navigation Links
Double mastectomy halves death risk for women with BRCA-related breast cancer
Date:2/12/2014

TORONTO, ON, February 11, 2014 Women with BRCA-related breast cancer who have a double mastectomy are nearly 50 per cent less likely to die of breast cancer within 20 years of diagnosis compared to women who have a single mastectomy, according to a new study led by Women's College Hospital's Kelly Metcalfe.

The findings, published in the British Medical Journal, suggest a double mastectomy may be an effective first-line treatment for women with early-stage breast cancer who carry a BRCA1 or BRCA2 genetic mutation. The BRCA1/2 genes belong to a class of genes that typically act to protect individuals from acquiring cancer, yet women who inherit a mutated form of the genes have a high risk of developing breast and ovarian cancers.

"Women with a BRCA mutation have a 60 to 70 per cent chance of developing breast cancer in their lifetime, and once diagnosed, a further 34 per cent chance of developing breast cancer in the opposite breast within 15 years," said Kelly Metcalfe, an adjunct scientist at Women's College Research Institute and professor at the University of Toronto. "For these women, we need to think about treating the first breast cancer, but also about preventing a second breast cancer."

To compare the survival rates of women with BRCA-related breast cancers, researchers assessed the medical records of 390 women with stage one or two breast cancer and a BRCA1 or BRCA2 mutation. The women were required to have been initially treated with a single or double mastectomy. The researchers found:

  • Women who had a double mastectomy had a 48% greater likelihood of surviving compared to women with a single mastectomy
  • For women who developed a new breast cancer in the opposite breast, the risk of dying of breast cancer was doubled
  • At twenty years, the survival rate was 88% for women with a double mastectomy and 66% for women with a single mastectomy

"Our study's results provide evide
'/>"/>

Contact: Julie Saccone
julie.saccone@wchospital.ca
416-323-6400 x4054
Women's College Hospital
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Obesitys Health Costs Double Earlier Estimates
2. Study finds number of battery-related emergency department visits by children more than doubles
3. Common acne medication doubles risk of eye infection
4. As Obesity Rates Rise, Cases of Kidney Stones Double: Study
5. Osteoarthritis risk not diminished in double bundle ACL surgeries
6. Moms Pot Use Doubles Risk of Preemie Birth: Study
7. Snacking and BMI linked to double effect of brain activity and self-control
8. MRSA cases in academic hospitals double in 5 years: study
9. Adding bavituximab to second-line chemotherapy doubles response rate
10. Double drug combo could shut down abnormal blood vessel growth that feeds disease
11. Early Menopause May Double Heart Disease Risk, Study Says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Balfleet.com , a leading dress company of wedding ... All the old and new customers can get a ... well-known for its high quality trendy women’s dresses, like ... more. Its formal dresses are quality made and come ... an elegant look when paired with any accessory. ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 Energy ... Bedsheets are now available. Celliant, the world’s leading ... sheets and pillowcases. , There are a number ... additional circulation, increased oxygenation and balanced body temperature; ... healing and pain relief; enhanced athletic performance; and ...
(Date:12/19/2014)... 2014 Eufaula, Oklahoma, located just 9 ... the state’s largest lake with more than 600 miles ... to a little more than 3,000 residents, hosted its ... the 6th of December. , Featuring Santa, Christmas lights ... Eufaula on Main Street. Narconon Arrowhead’s parade float ...
(Date:12/19/2014)... (PRWEB) December 20, 2014 The print ... Home and Business subscription of the Toronto Star, with ... readership of 622,169. The digital component is distributed nationally ... network of top news sites and partner outlets. To ... here . , The publication features an exclusive ...
(Date:12/19/2014)... 19, 2014 (HealthDay News) -- Potentially illness-causing E. coli ... at farmers markets, according to a new study. ... vendors from 13 farmers markets in Los Angeles and ... Out of almost 150 samples tested, 24 percent were ... salmonella, according to the researchers. Both types of ...
Breaking Medicine News(10 mins):Health News:Balfleet.com Announces Its Formal Dress Promotion For 2015 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3Health News:Mark DeMontis, Founder of Courage Canada, shares his passion for bringing hockey to those affected by blindness in Mediaplanet’s “Vision and Hearing” campaign 2Health News:E. Coli Germs Found on Farmers Market Herbs 2
... minor injuries from a series of explosions at an oil ... reported to have been triggered accidentally, but the matter is ... Trust maintained that only two people were in need of ... irritating the eyes, making people cough, and feel nauseous. The ...
... Organization has arrived in northwestern Pakistan to inspect the damage ... ,Lee is here to check on preparations being made for ... ,His agency says its main immediate task is to immunize ... off epidemics. Some 400,000 children have already been immunized against ...
... of its institution, Lasik, the eye surgery that corrects vision ... man. // An average procedure costs somewhere between $3,000 to ... ,Moreover, there are still question marks over the efficacy of ... is estimated that over 18 percent of the people require ...
... a New Year's resolution to get rid of her nicotine ... habit will have on her growing kids. // ,The ... two-year-old Cary are approaching an impressionable age, when kids become ... have to stop as my kids are at an age ...
... and her team from Virginia have developed a POCKET ... the personal information of the children.// The POCKET (Parental ... information of children’s who are using the internet for ... the applications may ask for personal information and the ...
... of breast cancer is the new nine week course of ... ,Herceptin is a monoclonal antibody that attacks the HER-2 ... breast cancers. ,The results of the combination therapy ... alone. ,A study was conducted by Finland researchers ...
Cached Medicine News:Health News:LASIK Treatments Still To Reach Common Man 2
(Date:12/19/2014)... and LYON, France , ... LLY ) and Adocia (Euronext Paris: FR0011184241 ... on developing an ultra-rapid insulin, known as BioChaperone Lispro, ... 2 diabetes. BioChaperone Lispro relies on Adocia,s proprietary BioChaperone® ... Lilly and Adocia will develop BioChaperone Lispro with ...
(Date:12/17/2014)... 2014 Revenue and earnings above the ... and development In the past 2013/14 fiscal year ... percent to EUR 4.287 billion (last year: EUR 4.190 billion) ... to EUR 360 million. "Overall, 2013/14 was a successful fiscal ... , President and CEO of Carl Zeiss AG. "Thanks to ...
(Date:12/17/2014)... Ariz. , Dec. 17, 2014  Beamz ... state-of-the-art interactive music products, today announced that it ... a leading manufacturer and supplier of innovative prosthetic, ... As part of the agreement, RSL Steeper ... bundled solution specifically configured for use within UK ...
Breaking Medicine Technology:Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 2Lilly and Adocia Announce Alliance to Co-Develop Ultra-Rapid Insulin Based on BioChaperone Technology 3ZEISS Asserts its Position in Difficult Environment 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 3
... PARK, Calif., Jan. 11 ForteBio®, Inc., a leading ... biotherapeutic and pharmaceutical products, today announced the launch of ... Kit for use on the company,s Octet platform. The ... measure levels of Protein A with unprecedented speed and ...
... , , CHICAGO, Jan. 11 ... single-database, fully-integrated electronic health record (EHR), practice management ... within a series of more than a dozen ... events today through January 15 at the Integrating ...
Cached Medicine Technology:ForteBio Launches New Dip and Read(TM) Residual Protein A Detection Kit; Introduces Sidekick(TM) Offline Biosensor Immobilization Station for All Octet(R) Instruments 2ForteBio Launches New Dip and Read(TM) Residual Protein A Detection Kit; Introduces Sidekick(TM) Offline Biosensor Immobilization Station for All Octet(R) Instruments 3Greenway Medical Technologies Advances Interoperability at Integrating the Healthcare Enterprise (IHE) North America Connectathon 2Greenway Medical Technologies Advances Interoperability at Integrating the Healthcare Enterprise (IHE) North America Connectathon 3Greenway Medical Technologies Advances Interoperability at Integrating the Healthcare Enterprise (IHE) North America Connectathon 4Greenway Medical Technologies Advances Interoperability at Integrating the Healthcare Enterprise (IHE) North America Connectathon 5
Trans-Blot Plus Gel/Cassette Assembly Tray...
PosiBlot 30-30 Masks...
A blotter fit for use with the incredible new Criterion precast gel system, the Criterion blotter combines excellent blotting efficiency with the flexibility of the Trans-Blot system and the ease-of-...
... using the Antigen-Antibody Pens-Using a proprietary and ... specialized fountain pens, called Antigen-Antibody pens-TM, that ... the blotting membranes in any form or ... colored dyes helps to see antigen being ...
Medicine Products: