Navigation Links
Double duty for blood pressure drugs: how they could revolutionize how we treat valve disease
Date:10/24/2011

Vancouver A type of medication known as angiotensin-receptor blockers could reduce risk of mortality in people with a heart disease called calcific aortic stenosis (AS) by 30 per cent over an eight-year period, Heart and Stroke Foundation researcher Dr. Philippe Pibarot told delegates at the Canadian Cardiovascular Congress. The condition is currently managed with open heart surgery.

"Our discovery shifts how we think about AS by looking at a new pathway which both prevents and reverses calcification," says Dr. Pibarot, a professor at Laval University and Canada Research Chair in Valvular Heart Diseases, Qubec Heart & Lung Institute. "It broadens how we can approach therapies, opening up new avenues of research, and has tremendous potential to lead to a major discovery."

From a health economics point of view, drug treatment is also far less expensive than replacing a valve through surgery, which Dr. Pibarot says costs at least $30,000.

Every year, AS is responsible for 10,000 to 15,000 deaths in North America, and upwards of 80,000 heart surgeries. Now, this promising research suggests the first possible drug therapy to treat AS.

"AS is one of the most common types of heart disease, yet the only option to save lives has been open heart surgery. And valve replacement surgery is the second most frequent heart surgery after coronary artery bypass," says Dr. Pibarot. "We may be able to slow the progress of AS to the point that most people won't need surgery."

Picture a normal heart valve as soft and thin, like a slice of tomato, Dr. Pibarot says. Compare that to a valve that has hardened and narrowed more like a cauliflower. That's calcific AS, the most common type of AS, where deposits of calcium form in the valve, which prevents it from opening properly and creates a dangerous 'pressure overload' within the heart.

For years, he notes, the assumption was that AS was a degenerative disease related to aging a
'/>"/>

Contact: Amanda Bates
amanda@curvecommunications.com
604-306-0027
Heart and Stroke Foundation of Canada
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Pot Smoking May More Than Double Crash Risk
2. Marijuana use may double the risk of accidents for drivers
3. Capacity to diagnose osteoporosis doubles in Armenia
4. Smoking May Double Risk for Stroke
5. Study examining large-scale data of double balloon enteroscopy shows it is safe and effective
6. ADHD Doubles a Childs Risk of Injury: Study
7. Double damage: Partner violence impacts mental health of over half-million Californians
8. C-Sections Linked to Doubled Risk for Blood Clots
9. Infections Among Those With Heart Devices Has Doubled: Study
10. Bone marrow transplant survival more than doubles for young high-risk leukemia patients
11. Too Much Sitting May Double Womens Risk of Blood Clots
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/7/2015)... 2015 When people think about protecting their ... their roofs than their basements. However, heavy rain falls also ... and basements. While flooding is an obvious problem in a ... unfinished areas dry to avoid a musty smell . ... Even small amounts of water can cause foundation damage, mold ...
(Date:5/7/2015)... Boston, MA (PRWEB) May 07, 2015 ... today the availability of its new free Alcohol ... is aimed at helping restaurant managers, professional bartenders, and ... earn their Alcohol Safety Certification. The material encompasses topics ... Upon completing the course, students can take the ServSafe ...
(Date:5/7/2015)... 07, 2015 “ Sky Hollywood Slots ” ... which takes a look at the latest and coolest applications ... the host of AppWatch and technology expert, conducted the app ... casino game that focuses on slots. , According to the ... traveled to Sin City in 2014. But what’s even more ...
(Date:5/7/2015)... Made with love at the Belvoir ... Vegan, no preservatives, no sweeteners or artificial colors and ... will delight every palate. , Belvoir Fruit Farms launched ... has grown successfully ever since. This range of refreshing ... opportunities as cocktail mixers. , Belvoir is available in ...
(Date:5/6/2015)... A poker run to raise funds for the 2015 National ... run will start at the United Veterans Club, 1914 W. Capital ... poker run, participants will visit checkpoints, drawing a card at each ... the end of the run. The run will start at the ... Tavern, Fairmont American Legion, Hastings DAV post, Kearney American Legion and ...
Breaking Medicine News(10 mins):Health News:Spring Storms Bring Musty Smell Inside 2Health News:Spring Storms Bring Musty Smell Inside 3Health News:Dynamic Path Adds Alcohol Safety Exam Prep Module to Test Preparation Offerings 2Health News:A Social Casino Game that Focuses on Slots Was Featured on NewsWatch Television 2Health News:Updated Contacts: Poker Run Fundraiser to Benefit National Veterans Golden Age Games 2
... This release is available in French . ... two can be spontaneously aggressive and that boys can be ... of boys will continue to be hyper-aggressive until the age ... sub-group of aggressive children has a different makeup than non-aggressive ...
... Inexpensive, well-established lab tests may hold the key ... which is the focus of World Kidney Day, March ... results in kidney failure, cardiovascular disease and anemia. ... percent over the past 10 years. But kidney disease ...
... others involved in tumor development , , TUESDAY, March 10 (HealthDay ... lower risk of developing pancreatic cancer, a finding that might ... , The study, by researchers at the Dana-Farber Cancer ... type and the disease, which is diagnosed in about 40,000 ...
... to Mount For Strawberry Nutrition BenefitsWATSONVILLE, Calif., March 10 ... of super foods that improve health and ... on time. A new study published in the scientific ... in strawberries help lower "bad" cholesterol.The study, conducted by ...
... technology programs implemented in New York state are active ... and could serve as models for new federal initiatives, ... Medical College. , "Programs such as these could transform ... says senior author Dr. Rainu Kaushal, chief of the ...
... Fee Offers Easy, Practical Strategies to Sleep Like a ... More...NEW YORK, March 10 Founder and CEO of ... announced her latest crusade -- educating people about the ... how to achieve high-quality sleep through her revolutionary wellness ...
Cached Medicine News:Health News:Perinatal environment influences aggression in children 2Health News:Upcoming World Kidney Day Underscores Role of Low-Cost Lab Tests in Combating High-Cost Kidney Disease 2Health News:Study Links Blood Type and Pancreatic Cancer 2Health News:Spoonfuls of Strawberries Help the Cholesterol Go Down 2Health News:Spoonfuls of Strawberries Help the Cholesterol Go Down 3Health News:New York State health IT strategy may be model for the nation 2Health News:New York State health IT strategy may be model for the nation 3Health News:Tired? Sleepless? ... New Sleep Program 'Good Night, Sleep Right(TM)' Launches in April 2009 2
(Date:5/6/2015)... -- 3D Communications announced today that ... pharmaceutical companies communicate the value of their drugs ... newly expanded 3D Market Access and Reimbursement ... develop and deliver their "Value Story". It will also ... stakeholders earlier in the "innovation-to-market" timeline, and incorporate ...
(Date:5/6/2015)... SAN ANTONIO , May 6, 2015   GenSpera, ... "Injectable Cancer Compositions" has entered the national phase application process ... , Eurasia, Japan , China ... the United States . When awarded, the resulting patent ... property around its entire platform technology, including its lead drug ...
(Date:5/6/2015)... Advanced wound care - assess products, developments, ... future hold for the advanced wound care ... potential revenues to 2025, assessing data, trends, opportunities and ... provides 115 tables, charts, and graphs covering 12 distinct ... industry and the future market prospects. You will see ...
Breaking Medicine Technology:3D Communications Expands Market Access and Reimbursement Communications Services for Pharmaceutical Companies 23D Communications Expands Market Access and Reimbursement Communications Services for Pharmaceutical Companies 3GenSpera Enters National Phase with Patent Application for Injectable Prodrug Formulations 2Advanced Wound Care Market Forecast 2015-2025: Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices 2Advanced Wound Care Market Forecast 2015-2025: Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices 3Advanced Wound Care Market Forecast 2015-2025: Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices 4Advanced Wound Care Market Forecast 2015-2025: Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices 5Advanced Wound Care Market Forecast 2015-2025: Prospects for Leading Companies in Wound Care Biologics, Moist Wound Care and Wound Care Devices 6
... Ohio, Sept. 13 AultCare has been using ... partnership with Cardiocom, released a white paper entitled, ... The paper describes the structure of the ... patient. Improved patient self-management has resulted in measurable ...
... 2010 Arena Pharmaceuticals, Inc. (Nasdaq: ARNA ... and webcast on Friday, September 17, 2010, at 7:00 ... US Food and Drug Administration (FDA) Endocrinologic and Metabolic ... meet on September 16, 2010, to review the lorcaserin ...
Cached Medicine Technology:AultCare/Cardiocom® White Paper Shows Telehealth Services Reduce ER Visits and Inpatient Stays for Patients 2Arena Pharmaceuticals to Host Conference Call and Webcast Following Lorcaserin FDA Advisory Committee Meeting 2Arena Pharmaceuticals to Host Conference Call and Webcast Following Lorcaserin FDA Advisory Committee Meeting 3
Open wire style 16 mm blade with a wing tip twist giving the surgeon better on-axis accessibility....
Angled upward 45 degrees for temporal approach. Open 14 mm blades....
Solid 16 mm blades. Self-locking mechanism. Dull finish....
Fenestrated 16 mm blades. Self-locking mechanism. Dull finish....
Medicine Products: