Navigation Links
Double Mastectomy Doesn't Improve Survival, Study Finds
Date:9/3/2014

By
HealthDay Reporter

TUESDAY, Sept. 2, 2014 (HealthDay News) -- More U.S. women with early stage breast cancer are choosing to have both breasts removed as a precautionary step, although the double mastectomy provides no apparent survival advantage, researchers say.

Death rates are similar for women who have both breasts taken off and those who opt for breast-conserving surgery known as lumpectomy, according to their new study.

"We found no lower death rates among women who had bilateral mastectomy compared to women who had breast-conserving surgery with radiation," said study researcher Scarlett Gomez, a research scientist at the Cancer Prevention Institute of California.

The results are important for women at average risk of breast cancer, Gomez and other experts said.

Tracking health data on more than 189,000 breast cancer patients in California, researchers found that the number of women opting for double -- or bilateral -- mastectomy jumped from 2 percent in 1998 to 12.3 percent in 2011.

One-third of women younger than 40 opted for a double mastectomy in 2011, compared to less than 4 percent at the study's start, the researchers said.

The study, published Sept. 3 in the Journal of the American Medical Association, followed most of the patients for at least seven years.

The preventive, or prophylactic, double mastectomy has been in the spotlight recently. In 2013, actress Angelina Jolie announced she had had a preventive double mastectomy because of a strong family history of breast and ovarian cancer. She'd also tested positive for the genetic mutation BRCA1, which raises breast cancer risk.

Gomez said her team realized the proportion of women opting for double mastectomy had surged in recent years and wanted to see what effect the more extensive surgery had on survival. The radical surgery is associated with higher costs, longer recovery and greater risk of complications.

Using information from a California cancer registry, they looked at survival after double mastectomy, breast-conserving therapy (lumpectomy) with radiation, and single mastectomy (removal of one breast) in women who had early cancer in one breast. The registry didn't include genetic information that might have indicated raised breast cancer risk.

Death rates were similar between women having double mastectomy and breast-conserving surgery, the researchers said. However, the death rate associated with single mastectomy was higher than the other procedures. "That is not a new finding," Gomez said. The higher rate is thought to be linked with other factors, such as the presence of other health conditions.

Over 10 years, survival was 83 percent for those who had lumpectomy, 81 percent for those who underwent double mastectomy and nearly 80 percent for a single mastectomy.

The findings echo those of other recent studies, Gomez said.

Women need this information when deciding on the surgical treatment of their breast cancer, Gomez said.

Oftentimes, survival rates are just one of many factors a woman considers when weighing surgical treatment for breast cancer, she said. A common reason for double mastectomy is fear of cancer recurrence, even though the fear usually exceeds the estimated risk, she said.

For some women, aesthetics are a key consideration, the researchers wrote. Some newer reconstruction techniques produce better breast symmetry if both are reconstructed at the same time.

Being informed is essential, said Dr. Lisa Newman, director of the Breast Care Center at the University of Michigan, who wrote an editorial accompanying the study. "Overall, I think the important message [from this study] for our breast cancer patients is there is no overwhelming survival advantage," she said.

As long as women understand the pros and cons of the procedures, "it really does become a very personal choice," she added.

Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society, agreed. Doctors need to communicate these study findings to their patients who are deciding about surgical treatment of their breast cancer, he said.

Lichtenfeld, who had no part in the study, advises women to take time after their diagnosis to learn about the pros and cons of each approach.

No matter which option she chooses, a woman's decision about surgical treatment needs to be respected, Lichtenfeld said. "If a woman is educated [about her options] and makes a decision, that is her decision."

More information

For more about surgical options for breast cancer, visit the American Cancer Society.

SOURCES: Scarlett Gomez, Ph.D., research scientist, Cancer Prevention Institute of California, Fremont; Lisa Newman, M.D., M.P.H., professor, surgery, and director, Breast Care Center, University of Michigan, Ann Arbor; Len Lichtenfeld, M.D., M.A.C.P., deputy chief medical officer, American Cancer Society; Sept. 3, 2014 JAMA


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Obesitys Health Costs Double Earlier Estimates
2. Study finds number of battery-related emergency department visits by children more than doubles
3. Common acne medication doubles risk of eye infection
4. As Obesity Rates Rise, Cases of Kidney Stones Double: Study
5. Osteoarthritis risk not diminished in double bundle ACL surgeries
6. Moms Pot Use Doubles Risk of Preemie Birth: Study
7. Snacking and BMI linked to double effect of brain activity and self-control
8. MRSA cases in academic hospitals double in 5 years: study
9. Adding bavituximab to second-line chemotherapy doubles response rate
10. Double drug combo could shut down abnormal blood vessel growth that feeds disease
11. Early Menopause May Double Heart Disease Risk, Study Says
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Double Mastectomy Doesn't Improve Survival, Study Finds
(Date:2/12/2016)... ... February 12, 2016 , ... The law firm of Morrow, ... Parishes. The purpose of these scholarships is to encourage applicants to pursue a ... seek employment within these two parishes. , “We have available jobs in St. ...
(Date:2/12/2016)... ... 2016 , ... CDRH Enforcement Trends: , Back to the Future , Feb. 25, 2016 — ... Churchill said, “Those who don’t learn from history are doomed to repeat it.” , An ... knocking this year. But that takes time. , Take a close look at the ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... As a ... hectic schedule, a demanding job, and no time to decompress, Rabinowitz found herself drawn ... herself to meditation for its impact on her life, implementing a 20-minute-per-day meditation practice ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ... Zuckerberg San Francisco General Hospital on April 5-7. The series is a multi-day, ... new habits. The workshops cover a broad range of topics, including coaching skills, ...
(Date:2/12/2016)... , ... February 12, 2016 , ... Fisher House Foundation ... Mayor John J. Lee, Nevada Military Support Alliance president Scott Bensing, and Peggy Kearns ... the VA Southern Nevada Healthcare System. This will be the first Fisher House ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... On Thursday, Feb. 11, 2016, surgeons at ... North Austin Medical Center successfully completed the first robotic ... Surgical System with Trumpf Medical,s advanced operating table, ... , M.D., colorectal surgeon at the Texas Institute for ... Motion technology, which seamlessly combines the da Vinci Xi ...
(Date:2/12/2016)... 12, 2016  Eli Lilly and Company (NYSE: LLY ... Alimta® (pemetrexed disodium) vitamin regimen patent would not presently be ... France , Italy and ... product only with dextrose solution.  --> ... Court of Appeal held that Lilly,s patent would be indirectly ...
(Date:2/12/2016)... Ga. , Feb. 12 2016  OMS Supply, ... dental and medical practitioners, announced today the recent launching ... offers visitors a variety of features that enhance the ... oral surgery supplies. --> ... is a fairly new company that started in early ...
Breaking Medicine Technology: