Navigation Links
Donor Stem-Cell Transplant Best For Acute Myeloid Leukemia
Date:6/9/2009

k. "For patients with poor-risk acute myeloid leukemia, the consensus has been they should all go to donor transplantation. For people in the biggest group, intermediate risk, there has really been no consensus," he said.

To determine which treatment is best for which patient, Koreth's team analyzed data from 24 clinical trials. They looked at the relapse-free survival and the benefit of allogeneic stem-cell transplantation vs. nonallogeneic stem-cell transplantation, plus chemotherapy for patients who had good, intermediate or poor survival risk.

The researchers found that patients with poor- and intermediate-risk AML who received allogeneic stem cell transplants -- the donor stem cells -- in first clinical remission were more likely to survive and less likely to suffer a relapse over the long term than patients given alternative therapies.

"For all comers, there is a statistically meaningful survival benefit to getting a donor transplant," Koreth said.

People in the poor-risk group had a survival advantage, which is consistent with current practice, he noted.

Without a donor transplant, the survival range for those in the poor-risk group is 15 percent to 20 percent at five years. With a donor transplant, the chance of disease-free survival at five years is about 33 percent.

For patients in the intermediate-risk group, a donor transplant was also clearly associated with improved survival -- of around 40 percent, Koreth said. This could become the new standard of care for these patients, he said.

"This is obviously not a home run yet," Koreth said. "We need better treatments, but for what we have today, this [donor cell transplantation] is a better treatment than the alternative."

Dr. Marshall A. Lichtman, professor of medicine, biochemistry and biophysics at the University of Rochester Medical Center, described the study as a very thoughtful analysis of a complex problem.

"I
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Exempla Healthcare Contracts For Talismans Quality Donor System
2. Brookings: Donor Perspectives on Innovative Financing for Global Health
3. Global Med Technologies(R), Inc. Submits ElDorado Donor(TM) to FDA
4. Female Blood Donor Concern May Be Unfounded
5. Generous Donors Allow Red Cross to Respond Swiftly and Effectively to California Wildfires
6. No increase in cardiovascular risk for living kidney donors
7. Study on Plasma-Depleted Cord Blood Transplantation Receives Best Abstract Award From The National Marrow Donor Program
8. Optimal systemic and splanchnic hemodynamic state after living-donor liver transplantation
9. American donors put faith (and dollars) in TAU cancer research
10. Living donors may be best source of insulin-producing islets for diabetes treatment
11. AST Emergence to Convergence Highlights the Latest High-Risk Organ Donor and Recipient Issues
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Donor Stem-Cell Transplant Best For Acute Myeloid Leukemia
(Date:9/30/2014)... September 30, 2014 Coast Dental ... opening of its newest practice, located at 1010 Shaw ... x-rays, general dentistry services , and specialty dental ... addition to providing affordable and convenient dental care, our ... dental appointments . Call Coast Dental at 559-777-6113 to ...
(Date:9/30/2014)... September 30, 2014 In its latest blog ... and believes that having family close by during a stay ... not the process is successful, is focusing on 5 reasons ... lasting recovery. , “Achieving sobriety is not a one-time event, ... Drug Rehabilitation’s CEO Per Wickstrom . “It’s an ongoing ...
(Date:9/30/2014)... 2014 More than 23 per cent of Canadians report ... stress increases the risk of poor mental and physical health, ... but for others especially those most likely to sweat ... , Thankfully, new research from Concordia University has found a ... huge help for healthcare professionals working to stop stress before ...
(Date:9/30/2014)... Rochelle, NY, September 30, 2014Levothyroxine (L-T4), long the ... in most patients, but some individuals do not ... about thyroid physiology may help to explain these ... Thyroid Association on thyroid hormone replacement reviewed the ... treatments to determine whether a change to the ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 OZ Naturals ... selling beauty brand on Amazon.com. , “The majority of ... respective beauty categories on Amazon.com,” said Craig Romero, CEO of ... UK on Amazon.co.uk and Canada on Amazon.ca , Romero went ... just launched earlier last month, are already taking over top ...
Breaking Medicine News(10 mins):Health News:Coast Dental Clovis Celebrates Grand Opening 2Health News:Coast Dental Clovis Celebrates Grand Opening 3Health News:New Best Drug Rehabilitation Blog Post Focuses on 5 Reasons Why Relapse Shouldn’t Stand in the Way of Recovery 2Health News:New Best Drug Rehabilitation Blog Post Focuses on 5 Reasons Why Relapse Shouldn’t Stand in the Way of Recovery 3Health News:How to predict who will suffer the most from stress 2Health News:New hypothyroidism treatment guidelines from American Thyroid Association 2Health News:OZ Naturals Now the No. 1 Selling Beauty Brand on Amazon.com 2Health News:OZ Naturals Now the No. 1 Selling Beauty Brand on Amazon.com 3
... More than nine million people, or 34 percent of ... drug benefit through Medicare Advantage plans with prescription drug ... Using just released data from the Center for ... database, Avalere researchers analyzed 2009 Medicare Part D open ...
... ST. LOUIS, Feb. 24 The deepening economic ... some would say failing -- health care,system at ... number of,uninsured and underinsured is rising. Also, faced ... those with insurance are not compliant in,taking critical ...
... and states reconsider funding for abstinence-only programs, the largest ... classes reveals that abstinence programs are plagued with factual ... and actively discourage the use of condoms to protect ... Texas Freedom Network Education Fund - Just Say ...
... women, but different genes might raise risk in black women ... a genetic marker that may indicate if a woman has ... says. , Shorter, white women who test positive for the ... to develop the muscular tumors in their uterus, according to ...
... study published in the February 2009 issue of the ... a highly reliable depression screening tool known as the ... and Europe can be effectively administered in resource poor ... needs have been underserved. The work also confirms that ...
... U.S. editors and producers traveled to Uganda last year ... fascinating countries. A highlight of the International Reporting Project ... and HIV/AIDS with Ugandan President Yoweri Museveni. At the ... three of the Gatekeepers will discuss the U.S. media,s ...
Cached Medicine News:Health News:1 in 3 Medicare Part D Enrollees Select Medicare Advantage Drug Plans for 2009 2Health News:Health and Wellness Programs in a Tight Economy: Why They Are Critical and How to Make Them Effective 2Health News:New Texas Study Reveals Serious Flaws in Abstinence Programs 2Health News:Inexpensive depression screening tool works in resource poor countries 2Health News:U.S. Media Report From Uganda: Wilson Center Panel Discusses Health, Environment, and Security in Africa 2
(Date:9/30/2014)... , N.J. and NEW BRUNSWICK, N.J., Sept. 30, 2014 /PRNewswire-USNewswire/ ... that allows Kessler Foundation and New Jersey Health ... research, education and patient care programs has been ... chief executive officer of Kessler Foundation and ... Health Foundation. "The experience of New ...
(Date:9/30/2014)... 2014  Georgia-Pacific Professional is a leading provider ... a wide range of away from home applications. ... in healthcare, including hospitals, long-term care facilities, surgical ... its healthcare products and solutions to the dental ... of infection control in the dental office," said ...
(Date:9/30/2014)... -- In a recent study it was ... the Eldor spinal needle 25G, 103 mm appeared significantly ... spinal needles of the same gauge and length of ... an excellent type of regional anesthesia for many operations ... It is estimated that 100 million patients worldwide ...
Breaking Medicine Technology:Kessler Foundation Partners with New Jersey Health Foundation To Start Innovative Companies To Change the Lives of People with Disabilities 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3
... SAN DIEGO, Sept. 26, 2011 Elevation Pharmaceuticals, Inc., ... aerosol therapies for patients with respiratory diseases, today announced ... and Chief Business Officer and Pravin Soni, PhD, as ... created positions. The company also announced that it drew ...
... 26, 2011 Clermont Pharmaceuticals, Inc., a ... positive results from a phase III trial ... latanoprost was compared to Xalatan® (latanoprost ophthalmic ... glaucoma.  Non-preserved latanoprost achieved the primary efficacy ...
Cached Medicine Technology:Elevation Pharmaceuticals Strengthens Management Team with Appointment of Executives 2Elevation Pharmaceuticals Strengthens Management Team with Appointment of Executives 3Clermont Pharmaceuticals Reports Positive Phase III Results for Drug to Treat Glaucoma 2
... multichannel pipettes speed up ... into microplates, with super ... volumes. The improved ergonomic ... multichannels, combined with super ...
... wide variety of applications. • Whole pipette is ... freely rotated against the handle to work in ... angle towards the microtiter plate. • The special ... common pipette tips, and provides a firm, parallel ...
Pipetman 8X200 Multichannel Pipette is an eight-channel, fully adjustable, air-displacement pipette having a useful volume range from 20 L to 200 L. Robustwith the usual Gilson qualities this pipette...
... multichannel pipettes speed up ... into microplates, with super ... volumes. The improved ergonomic ... multichannels, combined with super ...
Medicine Products: