Navigation Links
Dominion Diagnostics -- The Only Specialty Urine Drug Monitoring Laboratory to Offer Quantitative Detection of Tapentadol (Nucynta(TM)) by LC/MS/MS
Date:9/14/2009

NORTH KINGSTOWN, R.I., Sept. 14 /PRNewswire/ -- Dominion Diagnostics (Dominion) has recently developed and validated one of the first clinical quantitative assays for the drug tapentadol (Nucynta(TM)) performed by liquid chromatography/tandem mass spectrometry (LC/MS/MS). Tapentadol, recently approved for use by the FDA, is a centrally-active analgesic that has demonstrated efficacy in pain relief with improved gastrointestinal tolerability compared to other opioids for pain management.

Dominion's new assay by LC/MS/MS can detect and identify the primary drug tapentadol. Tapentadol is extensively metabolized in humans. In clinical studies 97% of the administered dose was metabolized, with 70% of the dose excreted in the urine in the conjugated form (55% as tapentadol-O-glucuronide and 15% and tapentadol-O-sulfate). Tapentadol excretion is almost exclusively renal. In a clinical study, it was shown that greater than 95% of a single dose of tapentadol was excreted in the urine within 24 hours of oral administration(1).

"This is a noteworthy achievement for our Research & Development (R&D) and Laboratory Teams," stated Chief Operating Officer Stephen Jordan. "Dominion has invested considerable time and resources in developing this new tapentadol assay. Providing assays for new pain medications allows us to better support our clients' need for relevant and accurate technologies when relying on urine drug monitoring to support patient adherence."

Dominion's quantitative tapentadol assay, one of the first presented to the industry, is now available to all clients across the country. This new development comes as part of Dominion's continued commitment to unparalleled laboratory excellence. Dominion continues to lead the industry in its quest for accurate, clinically relevant science for use in appropriately monitoring chronic pain patients. Dominion's R&D team actively works with leading assay manufacturers and pharmaceutical companies to develop accurate, specific tests that meet current and future needs of the growing pain management industry.

"Our LC/MS/MS assay for tapentadol is highly sensitive and offers clinicians an accurate means of detecting tapentadol in patients that are prescribed the drug, patients that may be diverting their medications, or in other cases where a patient may have been provided the drug from other sources," Dominion's Director of Research & Development Matthew Woodcock, Ph.D. commented. "At Dominion, we recognize the important clinical implications of urine drug monitoring, and we pride ourselves on offering scientifically accurate solutions to support every clinical scenario."

Source:

(1) Terlinden R et al., Eur J Drug Metab Pharmacokinet (2007); Jul-Sep 32(3): 163-169.

Nucynta(TM) is a registered trademark of Ortho-McNeil(R), Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc.

ABOUT DOMINION DIAGNOSTICS

Dominion Diagnostics is a premier provider of comprehensive clinical quantitative urine drug testing, medication monitoring and support services nationwide. For over 13 years, Dominion has provided services to thousands of clients in a variety of medical specialties, including Pain Medicine, Primary Care, Addiction Treatment, Behavioral Health, Psychiatry and Hospital Systems. Dominion is supported by a world-class team that shares a commitment to clinical and operational excellence. For more information about Dominion, please visit www.dominiondiagnostics.com.

    Contact:
    Julie Lenahan
    Director of Marketing
    Dominion Diagnostics
    (401) 667-0876
    jlenahan@dominiondiagnostics.com


'/>"/>
SOURCE Dominion Diagnostics
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Dominion Diagnostics to Host Open House Reception in New Vermont Laboratory Facility
2. Dominion Helps Communities by Donating $1 Million to Health Clinics
3. Capital BlueCross Acquires Dominion Dental
4. Dominion Diagnostics Announces Launch of Comprehensive New Company Website
5. Dominion Diagnostics Supports Rhode Islands Toys for Tots Initiative at Its 2007 Holiday Celebration
6. Quest Diagnostics To Speak at the Bank of America Merrill Lynch Global Healthcare Conference
7. Quest Diagnostics Marks Sixth Year on Dow Jones Sustainability Index
8. Reportlinker Adds Therapeutics and Diagnostics for Womens Disorders Report
9. Frost & Sullivan: Malaysia Diagnostics and Devices Industry Outlook 2009
10. Quest Diagnostics Declares Quarterly Cash Dividend
11. eCardio Diagnostics Expands Corporate Management Team
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... ... August 16, 2017 , ... The Data Council, the leading ... was acquired by Advantage Solutions. The Data Council’s IX-ONE platform is the ... industry’s leading suppliers, brokers, distributors and retailers. The Data Council will become a ...
(Date:8/16/2017)... ... August 16, 2017 , ... QualDerm Partners , a ... today announced Cumberland Skin Surgery and Dermatology has joined the company ... in both Hermitage and Lebanon, Tennessee, provides comprehensive general dermatology and skin cancer ...
(Date:8/16/2017)... ... August 16, 2017 , ... LabRoots , the leading provider of ... world, is excited to announce Andrew Ly as the winner of the LabRoots Summer ... costs. , Ly, who is in his third year at the University of ...
(Date:8/16/2017)... ... August 16, 2017 , ... Fusion Flix Inc., a Telly Award ... four countries and millions of viewers in a partnership with the Amazon Video Direct ... and fully available on Blu Ray disc in 2018. Proceeds will be going to ...
(Date:8/16/2017)... Houston, TX (PRWEB) , ... August 16, 2017 ... ... transforming digital health, announces their latest new client win in the healthcare market, ... and web-based solution to support healthcare staff and members. , AHF cares for ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... Aug. 2, 2017  Life Flight Network and PeaceHealth Oregon ... improves patient care and operational efficiency for patients at hospitals ... , Cottage Grove , and ... PeaceHealth and Life Flight Network work collaboratively to move patients ... or when a time sensitive emergency exists. ...
(Date:7/31/2017)... , July 31, 2017 Three Tru-D SmartUVC robots ... South Korea . Tru-D, short for "Total Room Ultraviolet Disinfection," ... rooms after an environmental services (ES) professional cleans the area with traditional ... Tru-D ... "Although the BAACH has ...
(Date:7/27/2017)... Biomet Holdings, Inc. (NYSE and SIX: ZBH) today reported financial ... Company reported second quarter net sales of $1.954 billion, ... and an increase of 2.1% on a constant currency ... the LDR Holding Corporation acquisition, second quarter 2017 revenues ... 0.3% on a constant currency basis. ...
Breaking Medicine Technology: