Navigation Links
Doing Angioplasty Long After Heart Attack Still Worth It, Analysis Shows
Date:2/25/2008

But author of one of studies in the review challenges the finding

MONDAY, Feb. 25 (HealthDay News) -- The artery-opening procedure called angioplasty does provide a benefit over drug therapy even if it's done long after a heart attack happens, a new analysis of studies claims.

However, that finding was immediately challenged by the leader of one of the studies that was analyzed.

"What we found is that putting all these studies together, altogether there is a marked survival benefit in favor of revascularization [angioplasty]," said Dr. Antonio Abbate, an assistant professor of medicine at Virginia Commonwealth University and lead author of the meta-analysis in the March 4 issue of the Journal of the American College of Cardiology.

"They're mixing apples and oranges," said Dr. Judith Hochman, the Harold Snyder Family professor of cardiology at New York University School of Medicine and leader of a widely publicized study reported in 2006 that found no such benefit. "The major principle of meta-analysis is that you include all studies that meet your criteria in an unbiased way. Their meta-analysis shows highly significant heterogeneity."

Specifically, the new analysis included six studies -- among them the one headed by Hochman -- of heart attack survivors who had completely blocked coronary arteries, and four studies of survivors with partially blocked arteries, she said.

That mixture produced "substantial flaws in terms of the violation of the principles of meta-analysis," Hochman said.

One of the studies included in the Abbate meta-analysis was a Swiss trial that he praised for having a much longer follow-up period than the Hochman study. The Swiss study followed participants for 10 years, while the follow-up in the Hochman trial was about three years. "In general, those studies that had a longer follow-up tended to show more benefit," Abbate said.

But that long follos" imgurl="http://image.bio-medicine.org/img/Doing-Angioplasty-Long-After-Heart-Attack-Still-Worth-It--Analysis-Shows.gif" timex="2/25/2008 3:04:35 PM" dirsub="(w-up period presents problems since it i...)" id="12661" index="medicine" dir="Doing Angioplasty Long After Heart Attack Still Worth It, Analysis Shows" dir2="Doing Angioplasty Long After Heart Attack Still Worth It, Anal..." keywords1=",medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news" keywords="Doing,Angioplasty,Long,After,Heart,Attack,Still,Worth,It,,Analysis,Shows" description="w-up period presents problems since it includes procedures done a dec...Statins are cholesterol-lowering drugs that are now widely prescribed ...The new meta-analysis is imperfect Abbate acknowledged. I'm not sayi...The report does not invalidate the current guidelines of the American ... The list of those who want mechanical intervention is not changed by ..." url=u&"/medicine-news-1/Doing-Angioplasty-Long-After-Heart-Attack-Still-Worth-It--Analysis-Shows-12661-2/" title="Doing%20Angioplasty%20Long%20After%20Heart%20Attack%20Still%20Worth%20It%2C%20Analysis%20Shows" %> Doing Angioplasty Long After Heart Attack Still Worth It, Anal... ( But author of one of studies in the r...)

Doing Angioplasty Long After Heart Attack Still Worth It, Analysis Shows
Date:2/25/2008

w-up period presents problems, since it includes procedures done a decade or more ago, Hochman noted. "Medical therapy 10 years ago was primitive," she said. "we didn't use high-dose statins. Some of the studies included began almost 20 years ago. So, is it relevant to look at studies that began 20 years ago and didn't use current optimum [medical] therapy?"

Statins are cholesterol-lowering drugs that are now widely prescribed for coronary problems.

The new meta-analysis is imperfect, Abbate acknowledged. "I'm not saying that it is the last word, but it helps us put things in perspective," he said. The study indicates that "if you take the entire group of patients after myocardial infarction [heart attack] who do not get revascularization within 12 hours, some groups will have a greater benefit from later revascularization," Abbate said.

The report does not invalidate the current guidelines of the American Heart Association and the American College of Cardiology, which recommend angioplasty within 12 hours of a heart attack and limit later use of the procedure to specific indications, Hochman said. The guidelines for a later angioplasty include cases where there is severe blockage of arteries, with severe symptoms, and where the left main coronary artery is affected, she said.

"The list of those who want mechanical intervention is not changed by this study," Hochman said.

More information

What angioplasty is and why it is done is explained by the U.S. National Heart, Lung, and Blood Institute.



SOURCES: Antonio Abbate, M.D., assistant professor, medicine, Virginia Commonwealth University, Richmond; Judith Hochman, Harold Snyder Family professor of cardiology, New York University, New York City; March 4, 2008, Journal of the American College of Cardiology


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Partial Face Transplant Patient Doing Well
2. Britney and K-Fed doing it all wrong, MU family researcher says
3. Adults With Diabetes Doing Better Prevention Job
4. Delayed angioplasty -- big bucks, no bang
5. Are women at greater risk from angioplasty?
6. Angioplasty Equals Bypass Surgery for Heart Patients: Study
7. On 30th Anniversary, Angioplasty Celebrated as Modern Medical Breakthrough in Stopping Heart Attack
8. 2 drugs equally effective for heart patients undergoing angioplasty, Mayo study finds
9. Many Patients Fail to Take Drugs After Heart Attack
10. The danger of blindness after ophthalmic surgery
11. Shoe Therapy Helps Survivors Celebrate Life After Abuse
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Doing Angioplasty Long After Heart Attack Still Worth It, Analysis Shows
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson ... Recently, he has implemented orthobiologic procedures as a method for treating his patients. ... the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons ...
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... OTTAWA, Ontario , June 27, 2016  VMS ... the Company,s Board will take whatever measures required to ... the Company,s stock which is currently listed on the ... S Wexler, Company Chairman and CEO, "We are seeing ... be difficult to understand, not only by the Company, ...
(Date:6/24/2016)... , June 24, 2016   Bay Area ... Network,s Dean Center for Tick Borne Illness ... and Rehabilitation, MIT Hacking Medicine, University of California, ... today announced the five finalists of Lyme ... disease.  More than 100 scientists, clinicians, researchers, entrepreneurs, ...
(Date:6/24/2016)... CLEMENTE, Calif. , June 24, 2016  American Respiratory Labs ... company, is now able to perform sophisticated lung assessments in patients, ... Technologies , Inc. Patients are no longer limited ... ndd,s EasyOne PRO ® , ARL patients like Jeanne R. of ... done in the comfort of her own home. ...
Breaking Medicine Technology: