Navigation Links
Dogs Help in Hunt for New Cancer Drugs
Date:3/23/2009

or 15 percent when applied to humans, added Bauer, who said he now directs scientific research at the Bauer Research Foundation in Port St. Lucie, Fla.

It's been five years since Oscar's death-sentence reprieve with the new drug, and he's still going strong.

Since then, three other dogs have been treated and have responded to the drug, called nitrosylcobalamin (NO-Cbl), without any negative reactions, Bauer said. He was to present the findings Monday at the national meeting of the American Chemical Society in Salt Lake City.

The research field appears so promising that the U.S. National Cancer Institute has established the Comparative Oncology Program to evaluate chemotherapy drugs in dogs.

And the first U.S. canine tumor tissue bank started accepting tissue and blood samples from dogs with cancer in 2007. The new "biospecimen repository" facility lies adjacent to the National Cancer Institute's own library of human cancer samples.

NO-Cbl works like a "Trojan horse," binding to vitamin B12 receptors on cell surfaces. This blocks the action of B12, which aids and abets the potentially deadly divide-and-multiply process of cancer cells.

Since Oscar, Bauer has treated a 13-year-old giant schnauzer named Haley with thyroid cancer and a 6-year-old Golden Retriever named Buddy with malignant peripheral nerve sheath tumor.

Buddy's tumor shrank 40 percent after 10 months of daily treatment, he said. Haley's shrank by 77 percent.

Bauer's group is now doing research with 10 dogs. They will be tracked for a year with the help of their own veterinarians. Based on the results of that research, Bauer said, he hopes to file for an investigational new drug application for NO-Cbl from the U.S. Food and Drug Administration for a phase I clinical trial on humans.

"There's a great inequity for drugs available for veterinary use and those available for human use," Bauer said. "Most of thos
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Survival differences by race most apparent in advanced stages of breast cancer
3. MRI finds breast cancer before it becomes dangerous
4. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
5. Pathway links inflammation, angiogenesis and breast cancer
6. Radiologists encouraged to look beyond cancer for clinically unseen diseases
7. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
8. Immune deficiency linked to a type of eye cancer
9. Drop in breast cancer incidence linked to hormone use, not mammograms
10. Breast cancer prevention practices vary across Canada
11. First biomarker discovered that predicts prostate cancer outcome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2015)... ... August 31, 2015 , ... In an article published ... Reconstructive Surgery Global Open Journal that discusses the future of 3-D printing technology as ... the future, customized implants, prosthetics, and other 3-D printed tools could be used to ...
(Date:8/31/2015)... Plains, NJ (PRWEB) , ... August 31, 2015 ... ... the Joint Replacement Surgery Program at Monmouth, was one of the first doctors ... decade, the results of this new approach have been impressive: faster recovery, decreased ...
(Date:8/31/2015)... Plains, NJ (PRWEB) , ... August 31, 2015 , ... ... as an “NJ Top Doc.” , At OSSMC, Dr. Kovatis treats all surgical and ... orthopedics and traumatic injuries to the entire musculoskeletal system, excluding the spine. , Dr. ...
(Date:8/31/2015)... ... August 31, 2015 , ... How can healthcare meet ... down costs? , In a commentary for The American Journal of Managed ... of “clinical efficacy,” which would bind parties together in agreements to intervene at ...
(Date:8/31/2015)... ... August 31, 2015 , ... ... at the 16th Innovations in Healthcare(SM) Awards Event , on October 21, ... (ABL) Organization , recognizes innovative organizations and individuals who are dramatically reducing the ...
Breaking Medicine News(10 mins):Health News:Recent Article on 3-D Printing Highlights the Future of Custom Medical Solutions Using the Technology, says Beverly Hills Physicians 2Health News:Recent Article on 3-D Printing Highlights the Future of Custom Medical Solutions Using the Technology, says Beverly Hills Physicians 3Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 2Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 3Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 4Health News:NJ Top Docs Presents, Dr. Paul Kovatis of Orthopedic Spine & Sports Medicine Center on his Five Year Anniversary as an "NJ Top Doc" 2Health News:How “Clinical Efficacy” Can Rein in Healthcare Costs 2Health News:How “Clinical Efficacy” Can Rein in Healthcare Costs 3Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 2Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 3Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 4Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 5Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 6Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 7Health News:9 Finalists Named for Innovations in Healthcare(SM) ABBY Awards; Winners to be Chosen October 21 in Long Beach, CA 8
... Ill. -- A growing number of health research programs ... groups help recruit study participants, obtain informed consent, collect ... But existing programs that educate researchers, community groups ... meet the needs of all groups that have a ...
... 2012 A new study finds differences in screening ... in colorectal cancer incidence and nearly 20 percent of ... stage-specific survival, which likely reflect differences in treatment account ... cancer mortality rates. The study, appearing early online in ...
... WEDNESDAY, May 2 (HealthDay News) -- Finding out who the ... emergence of a simple blood test for women that can ... The paternity screening, developed at a private biotech company in ... are done later in the pregnancy, its developer says. ...
... increases the life expectancy of men by 6.2 years and ... Copenhagen City Heart study presented at the EuroPRevent2012 meeting. ... Peter Schnohr told delegates that the study,s most recent analysis ... of jogging per week at a "slow or average" ...
... is currently the leading cause of pregnancy-related deaths during ... publication in The Endocrine Society,s Journal of Clinical ... adrenomedullin (ADM) may help predict this condition. TEP ... the fallopian tubes instead of in the uterus. In ...
... women aged 40-49 diagnosed with breast cancer on screening mammography report ... conducted at Elizabeth Wende Breast Care, LLC in Rochester, NY of ... out of 373 cancers (61%) were found in women, aged 40-49 ... the 228 patients did have a prior personal history of breast ...
Cached Medicine News:Health News:Better ethics education needed in community-based research 2Health News:Study says screening accounts for much of black/white disparity in colorectal cancer 2Health News:Who's the Dad? First-Trimester Blood Test May Tell 2Health News:Who's the Dad? First-Trimester Blood Test May Tell 3Health News:Regular jogging shows dramatic increase in life expectancy 2Health News:Regular jogging shows dramatic increase in life expectancy 3Health News:Hormone may help predict tubal ectopic pregnancy 2
(Date:8/31/2015)... , Aug. 31, 2015 Research and ... of the "Prescription Pain Drugs - Including ... - Global Markets, Competitors and Opportunities: 2015 - ... offering. Pain is defined as ... actual or potential tissue damage. At some point, ...
(Date:8/29/2015)... 29, 2015 La sofisticada ... los sistemas de imagen por Ultrasonidos   ofrece resultados ... examen rápidos y un flujo de trabajo   optimizado, ... el proceso de detección de Cardiopatías   ... hoy el lanzamiento europeo de HeartModel A.I ...
(Date:8/28/2015)... SOUTH SAN FRANCISCO, Calif. , Aug. 28, 2015 ... therapeutics for the treatment of cancer, today announced the ... the U.S. Securities and Exchange Commission (SEC) relating to ... The number of shares to be offered and the ... determined. CytomX intends to list its common stock under ...
Breaking Medicine Technology:Prescription Pain Drugs Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ Transdermal, Medical Marijuana - 2015-2020 Analysis and Forecasts 2Prescription Pain Drugs Including Opioid, Anticonvulsant, Injectable/ Inhaled, Topical/ Transdermal, Medical Marijuana - 2015-2020 Analysis and Forecasts 3Philips presenta HeartModel A.I en el Congreso ESC 2015 2Philips presenta HeartModel A.I en el Congreso ESC 2015 3Philips presenta HeartModel A.I en el Congreso ESC 2015 4Philips presenta HeartModel A.I en el Congreso ESC 2015 5CytomX Files Registration Statement for Proposed Initial Public Offering 2
... multiple sclerosis, remained relapse-free after three years of treatment ... active brain lesions - the ... - MS, a devastating disease causing progressive disability, affects 2.5 ... including many young adults - FTY720 regulatory filings planned before ...
... basis of methotrexate,resistance and differences in methotrexate response, ... analysis,of the genetic determinants of resistance to the ... could offer a,pathway to predicting such resistance and ... Children,s Research Hospital study., Besides its use ...
Cached Medicine Technology:FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment 2FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment 3FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment 4FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment 5FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment 6St. Jude Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia 2St. Jude Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia 3St. Jude Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia 4
The Plasma Extractor is used to express blood components from collection containers. The spring-loaded front panel exerts pressure on the collection container causing the fluid to transfer until cont...
The Eppendorf Maxipettor is a continuously adjustable pipette for precise pipetting of volumes up to 10 ml (in 10 l increments). Even liquids with a high vapor pressure or viscosity can be pipetted w...
... only catheter of its kind, the ... collects real-time cardiac electrical information, translating ... With 64 electrodes, this unique tool ... than 3,000 points of electrical data ...
... The St. Jude Medical® Pacing System Analyzer ... solution for implantation testing, programming and interrogation ... as an easy-to-use accessory to the St. ... testing by obtaining measurements of intrinsic P- ...
Medicine Products: