Dogs Help in Hunt for New Cancer Drugs (or 15 percent when applied to humans add...)

Navigation Links

Biology News Medicine News Biology Products Medicine Products Biology Definition Medicine Definition Biology Technology Medicine Technology Biology Dictionary Medicine Dictionary

HOME >> MEDICINE >> NEWS

Dogs Help in Hunt for New Cancer Drugs

Date:3/23/2009

or 15 percent when applied to humans, added Bauer, who said he now directs scientific research at the Bauer Research Foundation in Port St. Lucie, Fla.

It's been five years since Oscar's death-sentence reprieve with the new drug, and he's still going strong.

Since then, three other dogs have been treated and have responded to the drug, called nitrosylcobalamin (NO-Cbl), without any negative reactions, Bauer said. He was to present the findings Monday at the national meeting of the American Chemical Society in Salt Lake City.

The research field appears so promising that the U.S. National Cancer Institute has established the Comparative Oncology Program to evaluate chemotherapy drugs in dogs.

And the first U.S. canine tumor tissue bank started accepting tissue and blood samples from dogs with cancer in 2007. The new "biospecimen repository" facility lies adjacent to the National Cancer Institute's own library of human cancer samples.

NO-Cbl works like a "Trojan horse," binding to vitamin B12 receptors on cell surfaces. This blocks the action of B12, which aids and abets the potentially deadly divide-and-multiply process of cancer cells.

Since Oscar, Bauer has treated a 13-year-old giant schnauzer named Haley with thyroid cancer and a 6-year-old Golden Retriever named Buddy with malignant peripheral nerve sheath tumor.

Buddy's tumor shrank 40 percent after 10 months of daily treatment, he said. Haley's shrank by 77 percent.

Bauer's group is now doing research with 10 dogs. They will be tracked for a year with the help of their own veterinarians. Based on the results of that research, Bauer said, he hopes to file for an investigational new drug application for NO-Cbl from the U.S. Food and Drug Administration for a phase I clinical trial on humans.

"There's a great inequity for drugs available for veterinary use and those available for human use," Bauer said. "Most of thos
'/>"/>

1

GOOD

Page: 1 2 3
Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Survival differences by race most apparent in advanced stages of breast cancer
3. MRI finds breast cancer before it becomes dangerous
4. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
5. Pathway links inflammation, angiogenesis and breast cancer
6. Radiologists encouraged to look beyond cancer for clinically unseen diseases
7. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
8. Immune deficiency linked to a type of eye cancer
9. Drop in breast cancer incidence linked to hormone use, not mammograms
10. Breast cancer prevention practices vary across Canada
11. First biomarker discovered that predicts prostate cancer outcome

Post Your Comments:

(Date:5/22/2013)... 2013 The surging growth in specialty ... through marketing claims to compare mattresses often proves a ... a bed blog , offers shoppers faced with this ... their latest article. , Titled “ Mattress Comparison Overview ... guides readers through the basics of innerspring beds as ...

(Date:5/22/2013)... TX (PRWEB) May 22, 2013 ... sustainable practices in the textile industry, today released ... findings demonstrate that organic cotton production dropped 8% ... dramatic than the staggering 37% drop in 2010-11. ... production. , The report, Textile Exchange’s seventh, ...

(Date:5/22/2013)... Dr. Andrew Satlin offers patients with gum disease ... Assisted New Attachment Procedure (LANAP). May is Stroke Awareness Month, ... gum disease and stroke. Periodontal disease is one of the ... is linked to an increased risk for strokes because of ... pockets. , Periodontal disease is essentially an infection of ...

(Date:5/22/2013)... TWITTER: @the_USO & @SesameStreet are proud to ... in the next 6 months! , Today, the ... came together to show their heartfelt thanks to those who currently ... for distribution to our servicemen and women. The group was ... and the USO as well as the success of the ...

(Date:5/22/2013)... CHARLOTTE, (PRWEB) May 22, 2013 The ... fight against muscular dystrophy at the annual Charlotte Muscle ... $300,000 to help Charlotte-area families living with muscle disease. ... this year's event to support MDA families,” said MDA ... heroes who were partnered with a "Buddy" to make ...

Breaking Medicine News(10 mins):Health News:Mattress Comparison Overview Released by The Sleepy Shopper; Compares Top Types and Brands 2 Health News:Organic Cotton Sector Shows Signs of Stabilizing, Demonstrating Strength and Commitment of Producer Groups, According to 2011-12 Textile Exchange Farm & Fiber Report 2 Health News:Organic Cotton Sector Shows Signs of Stabilizing, Demonstrating Strength and Commitment of Producer Groups, According to 2011-12 Textile Exchange Farm & Fiber Report 3 Health News:Organic Cotton Sector Shows Signs of Stabilizing, Demonstrating Strength and Commitment of Producer Groups, According to 2011-12 Textile Exchange Farm & Fiber Report 4 Health News:For Stroke Awareness Month, Dr. Andrew Satlin is Raising Awareness of the Connections Between Gum Disease and Stroke and Offers Encino, CA Laser Gum Surgery for Treatment 2 Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 2 Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 3 Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 4 Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 5 Health News:Charlotte Muscle Team Event Raises $300,000 in the Fight Against Muscle Disease 2

[0] Mattress Comparison Overview Released by The Sleepy Shopper; Compares Top Types and Brands [0] Organic Cotton Sector Shows Signs of Stabilizing, Demonstrating Strength and Commitment of Producer Groups, According to 2011-12 Textile Exchange Farm & Fiber Report [0] For Stroke Awareness Month, Dr. Andrew Satlin is Raising Awareness of the Connections Between Gum Disease and Stroke and Offers Encino, CA Laser Gum Surgery for Treatment [0] The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC [0] Charlotte Muscle Team Event Raises $300,000 in the Fight Against Muscle Disease

... two surveys find , , THURSDAY, May 15 (HealthDay News) -- ... devices aren,t aware of recent recalls and don,t understand the ... they point to a lack of understanding among both doctors ... treat it, said Dr. Bruce Wilkoff, director of cardiac and ...

... minSURG Corporation, a,subsidiary of Orthopedic Development Corporation, ... used to treat chronic facet-oriented back,pain or to ... fuse each of the two facet joints in ... solutions to treat intractable back pain without,precluding other ...

... May 15 Nephros, Inc. (Amex: NEP ),announced today ... Recent Highlights -- Increased product revenues by ... U.S. trial for the OLpur(TM) H2H(TM) ... Joleen C. Turner as VP of Marketing and Business Development ...

... ... as a ,highlighted, poster at American Heart,Association Conference on Arteriosclerosis, Thrombosis and Vascular ... ... Inc. (TSX: PMD; Amex: PME) today announced unaudited financial,results for the first quarter ...

... hospital, they,re twice as likely to be injured, so prevention ... -- Stroke patients have a high risk of falling after ... , The University of Auckland researchers added that prevention programs ... a stroke fall almost twice as often as people who ...

... is,prepared to provide $10 million to support relief efforts ... This,contribution will assist the Red Cross Society of China, ... earthquake struck on,Monday, May 12. According to the latest ... many more are missing or trapped by debris., ...

Heart Device Recipients Often Not Aware of Recalls TruFUSE(R) Minimally Invasive Facet Fusion Procedure Tops 3,000 Spinal Levels Nephros Reports 2008 First Quarter Financial Results PreMD Reports First Quarter Results Stroke Patients at High Risk for Falls The American Red Cross Commits $10 Million to Assist China Earthquake Survivors

(Date:5/22/2013)... Advanced Prenatal Therapeutics (APT), a privately held ... alleviate the high blood pressure and other symptoms associated ... be the first medical device specifically designed to treat ... Every year, preeclampsia affects approximately 300,000 pregnant ... It is characterized by high blood pressure and proteinuria ...

(Date:5/22/2013)... NEW YORK , May 22, 2013 /PRNewswire/ ... is investigating potential claims on behalf of purchasers ... or the "Company") (NasdaqGS: AMAG -News). The investigation ... violated federal securities laws. On May ... 10.73% during intraday trading after the company announced ...

(Date:5/22/2013)... 2013 The Leukemia & Lymphoma Society (LLS) is ... LLC, a joint venture between ImmunGene and Caliber, to ... Phase I clinical trial for a novel fusion protein ... patients with indolent lymphomas who do not respond to ... IGN002, is a new class of biotherapeutics produced by ...

Breaking Medicine Technology:Advanced Prenatal Therapeutics - Using Targeted Apheresis to Treat Preeclampsia 2 Bronstein, Gewirtz & Grossman, LLC Announces Investigation of AMAG Pharmaceuticals, Inc. 2 The Leukemia & Lymphoma Society, Valor Biotherapeutics and ImmunGene Create Partnership to Advance Novel Therapy for Non-Hodgkin Lymphoma Patients 2 The Leukemia & Lymphoma Society, Valor Biotherapeutics and ImmunGene Create Partnership to Advance Novel Therapy for Non-Hodgkin Lymphoma Patients 3 The Leukemia & Lymphoma Society, Valor Biotherapeutics and ImmunGene Create Partnership to Advance Novel Therapy for Non-Hodgkin Lymphoma Patients 4

[0] Advanced Prenatal Therapeutics - Using Targeted Apheresis to Treat Preeclampsia [0] Bronstein, Gewirtz & Grossman, LLC Announces Investigation of AMAG Pharmaceuticals, Inc.[0] The Leukemia & Lymphoma Society, Valor Biotherapeutics and ImmunGene Create Partnership to Advance Novel Therapy for Non-Hodgkin Lymphoma Patients

... 2012 Niagara Thermal Products LLC is pleased to announce ... acquisition brings together two highly regarded names in the ... in the aerospace, defense and electronics markets. ... addition of Kittredge,s industry recognized dip brazing, welding, machining ...

... N.C., Jan. 23, 2012 As the influence of Managed ... that biopharma companies carry out as part of interacting ... device leaders have placed an increased importance on these ... closely intertwined with marketplace success. On average, ...

Cached Medicine Technology:Niagara Thermal Products LLC Announces the Acquisition of J. Kittredge & Sons, Inc. 2 Niagara Thermal Products LLC Announces the Acquisition of J. Kittredge & Sons, Inc. 3 Pharmaceutical Industry Places Newfound Emphasis on Managed Care Organizations 2 Pharmaceutical Industry Places Newfound Emphasis on Managed Care Organizations 3

Niagara Thermal Products LLC Announces the Acquisition of J. Kittredge & Sons, Inc.Pharmaceutical Industry Places Newfound Emphasis on Managed Care Organizations

... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...

... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...

... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...

Medicine Products:

Trig Tricyclic Antidepressant, Total Tricyclic Antidepressant Identification Quantitative, Serum Trichloraethanol (Chloral Hydrate Metabolite)