Navigation Links
Dog DNA May Yield Clues to Human Eczema
Date:5/10/2013

FRIDAY, May 10 (HealthDay News) -- A gene associated with eczema in dogs has been identified, and that might one day lead to better treatments for people with the skin disease, a new study contends.

The skin of patients with eczema -- whether canine or human -- is easily irritated by allergens such as pollens, house mites and certain foods. This irritation leads to itching, scratching and flaky skin that is vulnerable to infections.

Examining the DNA of dogs, the researchers found that a genetic region associated with eczema contains the gene PKP-2, which produces a protein important for the formation and proper functioning of skin structure. The finding suggests that an abnormal skin barrier is a potential risk factor for eczema, the study authors said.

"With the help of pet owners, we have managed to collect a unique set of DNA samples from sick and healthy dogs, which allowed us to gain insight into atopic dermatitis genetics," said first author Katarina Tengvall of Uppsala University in Sweden.

The findings, published online May 9 in the journal PLoS Genetics, could lead to better understanding of the disease, which may open the door to improved treatments and perhaps a genetic test for the condition, Tengvall said in a journal news release.

Eczema affects 10 percent to 30 percent of people and up to 10 percent of dogs. Purebred German shepherds are prone to eczema because of generations of selective breeding, the researchers said.

For the study, the researchers compared DNA samples from healthy dogs with DNA samples from German shepherds that had eczema to locate the particular genetic segment associated with the disease. Compared to human DNA, the structure of canine DNA makes it easier to locate areas that carry disease-risk genes, the researchers said.

The similarity between canine and human eczema was underscored by another recent discovery, the researchers said. In that case, a gene involved in the skin barrier was linked to human eczema.

More information

The American Academy of Family Physicians has more about eczema.

-- Robert Preidt

SOURCE: Uppsala University, news release, May 9, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Minimally Invasive Surgery for Treatment of Colorectal Cancer Yields Optimal Outcomes for Patients
2. Brain Circuitry Yields Clue to Autism, Researchers Say
3. Round or shaped, implants yield good results in breast reconstruction
4. NOAA: Tortugas marine reserve yields more, larger fish
5. Study of cancer cell metabolism yields new insights on leukemia
6. Gene Study Yields New Clues to Crohns Disease, Colitis
7. Cell death mystery yields new suspect for cancer drug development
8. Reconstructed 1918 influenza virus has yielded key insights, scientists say
9. Anti-clotting drugs yield similar results
10. Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research
11. Genomic study of rare childrens cancer yields possible prognostic tool
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Dog DNA May Yield Clues to Human Eczema
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... ... business simulation -centric training, today announced the launch of a new research study, ... having the skills needed to execute that strategy, and the actual success of ...
(Date:3/27/2017)... Georgia (PRWEB) , ... March 27, 2017 , ... ... to announce that for a second year in a row; they are the ... healthcare designers in the industry voted on the award at Design Connections 2017. ...
(Date:3/27/2017)... ... ... still in shock after receiving a $2,500 Academic Award from California Casualty . “This ... She thinks the coming week is going to be a very joyful for her classroom. ... students.” , The award will allow the 4th grade teacher at Tumwater Hill Elementary School ...
(Date:3/27/2017)... ... March 27, 2017 , ... The Anaheim Hills office ... First National Capital has added 10 new sales professionals over the past 6 months ... by 15 additional new hires over the course of 2017. , “This new ...
(Date:3/27/2017)... ... March 27, 2017 , ... ... announce the launch of a months-long rebranding effort. This includes the introduction of ... focus group discussions and market research, we learned that a simple, proactive approach ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... , March 27, 2017 FinancialBuzz.com News Commentary  ... According to a new report ... North America , grew 34 percent to $6.7 billion and can ... of (CAGR) over the next five years, from $6.7 billion in 2016, ... Americans that will be able to purchase cannabis without a doctor,s recommendation. ...
(Date:3/27/2017)... March 27, 2017   Pulmatrix, Inc . (NASDAQ: PULM), ... address serious pulmonary diseases, today announced that it has added ... fibrosis and asthma to its Scientific Advisory Board . ... Richard B. Moss , MD, former chief of the ... Cystic Fibrosis Center at Stanford University, and ...
(Date:3/27/2017)... March 27, 2017 The global ... USD 16.0 billion by 2025, according to a new ... of chronic diseases is anticipated to be responsible for ... thereby widens the scope for growth during the forecast ... population, which is highly susceptible to chronic diseases, is ...
Breaking Medicine Technology: