Navigation Links
Dog DNA May Yield Clues to Human Eczema
Date:5/10/2013

FRIDAY, May 10 (HealthDay News) -- A gene associated with eczema in dogs has been identified, and that might one day lead to better treatments for people with the skin disease, a new study contends.

The skin of patients with eczema -- whether canine or human -- is easily irritated by allergens such as pollens, house mites and certain foods. This irritation leads to itching, scratching and flaky skin that is vulnerable to infections.

Examining the DNA of dogs, the researchers found that a genetic region associated with eczema contains the gene PKP-2, which produces a protein important for the formation and proper functioning of skin structure. The finding suggests that an abnormal skin barrier is a potential risk factor for eczema, the study authors said.

"With the help of pet owners, we have managed to collect a unique set of DNA samples from sick and healthy dogs, which allowed us to gain insight into atopic dermatitis genetics," said first author Katarina Tengvall of Uppsala University in Sweden.

The findings, published online May 9 in the journal PLoS Genetics, could lead to better understanding of the disease, which may open the door to improved treatments and perhaps a genetic test for the condition, Tengvall said in a journal news release.

Eczema affects 10 percent to 30 percent of people and up to 10 percent of dogs. Purebred German shepherds are prone to eczema because of generations of selective breeding, the researchers said.

For the study, the researchers compared DNA samples from healthy dogs with DNA samples from German shepherds that had eczema to locate the particular genetic segment associated with the disease. Compared to human DNA, the structure of canine DNA makes it easier to locate areas that carry disease-risk genes, the researchers said.

The similarity between canine and human eczema was underscored by another recent discovery, the researchers said. In that case, a
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Minimally Invasive Surgery for Treatment of Colorectal Cancer Yields Optimal Outcomes for Patients
2. Brain Circuitry Yields Clue to Autism, Researchers Say
3. Round or shaped, implants yield good results in breast reconstruction
4. NOAA: Tortugas marine reserve yields more, larger fish
5. Study of cancer cell metabolism yields new insights on leukemia
6. Gene Study Yields New Clues to Crohns Disease, Colitis
7. Cell death mystery yields new suspect for cancer drug development
8. Reconstructed 1918 influenza virus has yielded key insights, scientists say
9. Anti-clotting drugs yield similar results
10. Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research
11. Genomic study of rare childrens cancer yields possible prognostic tool
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Dog DNA May Yield Clues to Human Eczema
(Date:8/19/2014)... LunaDress, a popular supplier of fashionable ... ladies, is now providing a discount of up to ... company’s cheap white prom outfits are available in different ... outfits. , There are over 400 cheap white ... the special offer is valid until August 29, 2014. ...
(Date:8/19/2014)... (PRWEB) August 20, 2014 Recently, iFitDress.com,a ... occasion outfits, has unveiled its new collection of ... made to expand the company’s global market. Each item ... to the company’s senior spokesman, customers that have specific ... at iFitDress.com. Now, all the brand new items are ...
(Date:8/19/2014)... 2014 The National Cannabis Industry ... Southwest CannaBusiness Symposium on Saturday, August 23, from ... in Las Vegas. , Featuring keynotes by U.S. Representative ... (D-Las Vegas), the event will also include in-depth discussions ... NCIA is doing federally to advance a legitimate and ...
(Date:8/19/2014)... Drews Dental Services is proud to announce the recent election ... Maine Dental Association (MDA). After serving on the Executive Board ... been sworn in to his new position. , Dr. Drews ... and being a part of the ADA House of Delegates ... 2015. He plans to advocate for the profession of dentistry ...
(Date:8/19/2014)... Tara Haelle HealthDay ... -- Kidney injury can be added to the list ... medications often prescribed to treat behavioral symptoms of dementia ... (Seroquel), risperidone (Risperdal) and olanzapine (Zyprexa) are approved by ... disorder, schizophrenia and other serious mental disorders. They are ...
Breaking Medicine News(10 mins):Health News:Popular Supplier LunaDress Providing an Exclusive Assortment of White Prom Dresses at a Discount of Up to 67% 2Health News:Discounted Pewter Evening Dresses For 2014 Unveiled By Company iFitDress.com 2Health News:SATURDAY IN LAS VEGAS: U.S. Rep. Dina Titus, State Sen. Tick Segerblom Keynote National Cannabis Industry Association Southwest CannaBusiness Symposium 2Health News:Dr. Drews Elected VP of Maine Dental Association 2Health News:Certain Antipsychotic Meds Tied to Kidney Problems in Elderly 2Health News:Certain Antipsychotic Meds Tied to Kidney Problems in Elderly 3
... Five former directors of the Population and Reproductive Health ... (USAID) today urged the new Obama administration to move ... . The former directors issued a joint report, ... Assistance, as Barack Obama takes office as president. ...
... K. Shinseki took the oath of office today as ... leadership of the Department of Veterans Affairs following Tuesday,s ... from my first day in office is to make ... focused on the Nation,s Veterans as its clients," Shinseki ...
... 21 The following statement can be attributed ... BlueCross:"Capital BlueCross has consistently said two things: We ... other merger. But we have urged public policy ... this proposed merger without conditions, because without conditions ...
... low levels of sexual desire, often as a result of ... physical symptoms such as back pain and memory problems than ... new study by researchers at the University of North Carolina ... study, published recently as an online early view article in ...
... history was made 10 years ago, greatly impacting the ... when a team of surgeons performed the first hand ... procedure, also called composite tissue allotransplantation, criticized by some ... in the world of organ transplantation, has continued to ...
... IDEXX Laboratories, Inc. (Nasdaq: IDXX ), has scheduled ... results for Friday, January 30, at approximately 7:00 a.m. (eastern). ... 9:00 a.m. (eastern) on that day. Individuals can access a ... the IDEXX Web site, www.idexx.com . An archived edition ...
Cached Medicine News:Health News:Five Former USAID Officials Ask Obama for Leadership on Family Planning 2Health News:Shinseki Sworn In, Vows 21st Century Service to Veterans 2Health News:Capital Blue Cross Issues Statement on Withdrawal of Merger 2Health News:UNC study: Postmenopausal women's loss of sexual desire affects health, quality of life 2Health News:Hand Transplantation Marks Historical 10-Year Milestone 2Health News:Hand Transplantation Marks Historical 10-Year Milestone 3Health News:Hand Transplantation Marks Historical 10-Year Milestone 4
(Date:8/19/2014)... 2014 ,Weight Loss- Market Analysis, ... report provides comprehensive insights about phase III pipeline drugs ... of the report is to establish the understanding for ... across the different countries and regions. While the leading ... also provides details on the drug master filings across ...
(Date:8/18/2014)... Calif. , Aug. 18, 2014 ... therapeutics to treat infectious diseases, has announced intentions ... the treatment of the current Ebola Virus outbreak ... the use of GBV006, a combination of Food ... established compassionate use regulatory pathway.  The discovery of ...
(Date:8/18/2014)... 2014  Pharmacyclics, Inc. (NASDAQ: PCYC ) ... Tomasello as its Chief Commercial Officer.  Ms. Cline ... of the Americas, Hematology and Oncology, for the Celgene ... Prior to joining Celgene, Ms. Cline Tomasello was the ... Genentech, where she was responsible for over $1.7 billion ...
Breaking Medicine Technology:Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 2Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 3Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 4Globavir Seeking Approval and Launch of Novel Ebola Treatment Before Year End 2Globavir Seeking Approval and Launch of Novel Ebola Treatment Before Year End 3Globavir Seeking Approval and Launch of Novel Ebola Treatment Before Year End 4Pharmacyclics Appoints Chief Commercial Officer 2Pharmacyclics Appoints Chief Commercial Officer 3Pharmacyclics Appoints Chief Commercial Officer 4
... DELAND, Fla., May 13 USHIFU, LLC, the clinical ... pleased,to announce conditional written approval pending minor changes to ... for the treatment of,recurrent prostate cancer with the Sonablate(R) ... Dr. Herbert Lepor, Chairman of Urology at NYU ...
... Products Expand Infection Prevention Business, DUBLIN, Ohio, ... products and services that improve the safety and,productivity ... the,acquisition of assets of privately held Enturia, Inc., ... ChloraPrep(R) brand name., ChloraPrep(R) brand products are ...
Cached Medicine Technology:FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer 2Cardinal Health Completes Enturia Acquisition 2
... The Awaya stereo test was developed to ... Awaya Stereo test employs the more reliable ... eye. It is not dependent on polarizing spectacles ... first target is an attractive image of a ...
... is designed to assist patients with red-green color ... filter cuts off wavelengths shorter than 582 nm ... of their most difficult color distinctions. A color ... determine whether a color is in the longer ...
Features a twist-on backswitch, with a diffused, cobalt blue light beam....
Heavy duty, all purpose illuminator available in blue and green. Unique Clip Switch automatically turns off when returned to pocket. Pre-focused lens tip Heine XHL Halogen bulb for bright, concentra...
Medicine Products: