Navigation Links
Does probiotic intervention induce the serum global lipid profile change?
Date:9/17/2008

The new global metabolic profiling techniques, like lipidomics as a branch of metabolomics, have made it possible to measure large numbers of different metabolites, and are currently being applied to increase our understanding of the health and disease continuum.

A Finland research group investigated the effect of a three weeks intervention of a probiotic LGG intervention on serum global lipidomics profiles in healthy adults. This will be published on 28 May 2008, in the World Journal of Gastroenterology. The result showed that there were decreases in the levels of lysophosphatidylcholines (LysoGPCho), sphingomyelins (SM) and several glycerophosphatidylcholines (GPCho), and increases in triacylglycerols (TAG) in the probiotic LGG group. These changes may contribute, for example, to the metabolic events behind the beneficial effects of LGG on gut barrier function seen in previous studies.

This study, done in collaboration with research groups of Associate Professor Riitta Korpela and Professor Matej Oreič, was the first to characterise the effect of probiotics on global lipidomics profiles. There were indications that probiotic LGG intervention may lead to changes in global lipidomics profiles reflected in decreased LysoGPCho and SM, mainly decreased GPCho and mainly elevated TAG. In addition, among the inflammatory variables, IL-6 was moderately associated by changes in global lipidomics profiles, while there was only a weak association between the lipidomics profiles and the two other inflammatory markers, TNF-αand CRP.

The new analytical capacity of lipidomics as a branch of metabolomics can increase our understanding of lipid biology, improve the characterisation of global lipid profiles and result in the identification of previously unknown changes in lipid metabolism. Probiotics have been mostly studied in the prevention and treatment of different gastrointestinal diseases and allergy, but the action mechanisms of probiotics are poorly understood. Metabolomics may provide powerful tools for identifying new biomarkers behind the clinical effects of probiotic intervention trials and for establishing relationships between molecular profiles and other known data from the same individual.


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Applegate Farms Launches the Companys First Yogurt Cheese with Probiotics
2. Introducing GoodBelly(TM) the New Probiotic Fruit Drink Line
3. ReachMD XM 157 Announces Medical Information Feature on Irritable Bowel Syndrome, Its Treatments, and the Role of Probiotics
4. Probiotics Help Adult Weight Loss After Bariatric Surgery
5. Probiotics May Benefit Health and Quality of Life of Older People
6. Report raises C. diff concerns; yeast-based probiotic shown to help significantly reduce recurrence
7. Wildwood Organics Introduces Probiotic Soymilk(TM)
8. Probiotics affect metabolism, says new study
9. Dallas Among the First to Offer Probiotic Supplement Align(R)
10. Probiotics Play Critical Role in Pediatric Health and Immunity
11. Review of probiotic research finds only Bifantis can claim efficacy vs. placebo for IBS symptoms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... Sacramento, California (PRWEB) , ... September 22, 2017 , ... ... person at a time - carries it into the entertaining and delicious worlds ... year, Matt Gersper (founder of Happy Living) convinced him to turn his play into ...
(Date:9/22/2017)... ... September 22, 2017 , ... “Cursed with ... an obligatory tithe, and the freedom experienced when breaking free from this misconception. ... author, Lysa M. Harrison. , Published by Christian Faith Publishing, Lysa M. Harrison’s ...
(Date:9/22/2017)... ... September 22, 2017 , ... ... emergency rooms is celebrating the one year anniversary of its Houston-Fallbrook facility. ... said Dr. Otinwa, Facility Medical Director of First Choice Emergency Room Houston-Fallbrook. “It ...
(Date:9/22/2017)... ... September 22, 2017 , ... Silicon ... effectively even on the go. Their electric toothbrushes aggressively attack oral bacteria by ... UV sanitizing technology. Combining leading edge Enke technology with a premium timeless design, ...
(Date:9/22/2017)... ... September 22, 2017 , ... “Letters From Home”: ... even the lost, have value to God. “Letters From Home” is the creation of ... member of the President’s Cabinet of Jerry Savelle Ministries International, who has traveled and ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... SAN FRANCISCO , Sept. 12, 2017 /PRNewswire/ ... Lifecycle Management Solutions (VLMS), is pleased to announce ... as a member of its Board of Directors ... 2017. ValGenesis VLMS enables life science companies to ... eliminate the use of paper in this process. ...
(Date:9/7/2017)... nearly two decades, New Life Agency has been committed to providing the ... Life Agency announces a powerful three-way partnership designed to deliver substantial savings ... ... http://www.schrafts2.com/ (PRNewsfoto/PharmaCareCard) ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ...
(Date:9/6/2017)... , Sept. 6, 2017  Robert G. Szewc, M.D., ... Professional Member in recognition of his contributions to the ... as a Nephrologist at the practice of Kidney and ... kidney care and hypertension solutions. He has worked in ... of career experience, as well as expertise in kidneys, ...
Breaking Medicine Technology: