Navigation Links
Does night work put women's health at risk?
Date:6/19/2012

Breast cancer is the number one cause of female mortality. It affects 100 out of 100,000 women per year in developed countries. Each year, more than 1.3 million new cases are diagnosed, 53,000 of these in France.

The risk factors of breast cancer are varied. They include genetic mutations, late first pregnancy, low parity or hormone therapy, but other causes of breast cancer such as way of life, environmental or professional causes have not yet been completely identified.

In 2010, based on experimental and epidemiological work, the International Agency for Research on Cancer (IARC) classified work that disturbed the circadian rhythm as being "probably carcinogenic". The circadian rhythm, that regulates the alternation between wakefulness and sleep, controls numerous biological functions and is altered in people who work at night or who have disrupted working hours. Several hypotheses have been put forward to explain the observed links between night work and breast cancer: exposure to light during the night, that eliminates the nocturnal melatonin surge and its anti-carcinogenic effects, disturbed functioning of the biological clock genes that control cell proliferation, or sleep disorders that can weaken the immune system.

So the Inserm researchers examined the effect of night work on the health of women in a major population study carried out in France between 2005 and 2008. The careers of 3000 women were examined, including each period of night work. In total, over 11% of women had worked nights at some time during their career.

The risk of developing breast cancer was 30% higher in women who had worked nights compared to women who had never worked nights. This increased risk was particularly marked in women who had worked nights for over four years, or in women whose working rhythm was less than 3 nights per week, because this led to more frequent disturbances between night and day rhythms.

Finally, the link between night work and breast cancer seemed to be more marked when we looked at women who had worked at night prior to a first pregnancy. An explanation for this result could be that the mammary cells, incompletely differentiated in women before their first pregnancy, are more vulnerable.

"Our work has corroborated the results of previous studies and poses the problem of taking night work into consideration in public health management, especially since the number of women working atypical hours is on the increase", states Pascal Gunel, the main author of this work.


'/>"/>
Contact: Press Inserm
presse@inserm.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

Related medicine news :

1. Super Models Line Up to Walk The Catwalk and Celebrate Vogue's Fashion Night Out in LA
2. Night Shift Might Boost Womens Breast Cancer Risk: Study
3. Intensivists at night improve patient outcomes in some ICUs, says Pitt/UPMC team
4. Night Staffing With Critical Care Docs May Lower ICU Death Rates
5. Can a standard vision test predict nighttime driving performance?
6. Sprout Healthy Vending Lands More Machines in the Lone Star State
7. Insulite Labs announces the launch of the PCOS Inspiration Hour, a one hour virtual gathering place for women with PCOS and other women’s health issues to come together.
8. Qualicode and CellTrak Deliver Integrated Mobile Scheduling and Health Record Solution
9. FirstVitals Health and Wellness, Inc. awarded $4 Million CMS Innovation Grant for Unique Telehealth Diabetes Progam Focused on Glycemic Control and Prevention of Diabetic Foot Complications
10. Zane Benefits Announces Wellness HRAs: A New Way to Reward Healthy Employees
11. Seattle Physician Shares Health IT Story in the Nation’s Capital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment center ... Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This annual ... the world’s leading providers of cereal and other breakfast foods. Its residents often refer ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle ... chronic pain and the benefits of holistic treatments, Serenity Recovery Center of ... Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening ... industry leaders in advanced audiology and hearing aid technology, ... ™, the world,s first internet connected hearing aid that ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... ,world firsts,: , TwinLink™ - the first ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Surgical Procedure Volumes: Global Analysis (United States, ... Australia, Canada)" report to their offering. ... an essential tool for healthcare business planners, provides surgical ... looks at surgery trends with an in-depth analysis of ...
Breaking Medicine Technology: