Navigation Links
Does night work put women's health at risk?

Breast cancer is the number one cause of female mortality. It affects 100 out of 100,000 women per year in developed countries. Each year, more than 1.3 million new cases are diagnosed, 53,000 of these in France.

The risk factors of breast cancer are varied. They include genetic mutations, late first pregnancy, low parity or hormone therapy, but other causes of breast cancer such as way of life, environmental or professional causes have not yet been completely identified.

In 2010, based on experimental and epidemiological work, the International Agency for Research on Cancer (IARC) classified work that disturbed the circadian rhythm as being "probably carcinogenic". The circadian rhythm, that regulates the alternation between wakefulness and sleep, controls numerous biological functions and is altered in people who work at night or who have disrupted working hours. Several hypotheses have been put forward to explain the observed links between night work and breast cancer: exposure to light during the night, that eliminates the nocturnal melatonin surge and its anti-carcinogenic effects, disturbed functioning of the biological clock genes that control cell proliferation, or sleep disorders that can weaken the immune system.

So the Inserm researchers examined the effect of night work on the health of women in a major population study carried out in France between 2005 and 2008. The careers of 3000 women were examined, including each period of night work. In total, over 11% of women had worked nights at some time during their career.

The risk of developing breast cancer was 30% higher in women who had worked nights compared to women who had never worked nights. This increased risk was particularly marked in women who had worked nights for over four years, or in women whose working rhythm was less than 3 nights per week, because this led to more frequent disturbances between night and day rhythms.

Finally, the link between night work and breast cancer seemed to be more marked when we looked at women who had worked at night prior to a first pregnancy. An explanation for this result could be that the mammary cells, incompletely differentiated in women before their first pregnancy, are more vulnerable.

"Our work has corroborated the results of previous studies and poses the problem of taking night work into consideration in public health management, especially since the number of women working atypical hours is on the increase", states Pascal Gunel, the main author of this work.

Contact: Press Inserm
INSERM (Institut national de la sant et de la recherche mdicale)

Related medicine news :

1. Super Models Line Up to Walk The Catwalk and Celebrate Vogue's Fashion Night Out in LA
2. Night Shift Might Boost Womens Breast Cancer Risk: Study
3. Intensivists at night improve patient outcomes in some ICUs, says Pitt/UPMC team
4. Night Staffing With Critical Care Docs May Lower ICU Death Rates
5. Can a standard vision test predict nighttime driving performance?
6. Sprout Healthy Vending Lands More Machines in the Lone Star State
7. Insulite Labs announces the launch of the PCOS Inspiration Hour, a one hour virtual gathering place for women with PCOS and other women’s health issues to come together.
8. Qualicode and CellTrak Deliver Integrated Mobile Scheduling and Health Record Solution
9. FirstVitals Health and Wellness, Inc. awarded $4 Million CMS Innovation Grant for Unique Telehealth Diabetes Progam Focused on Glycemic Control and Prevention of Diabetic Foot Complications
10. Zane Benefits Announces Wellness HRAs: A New Way to Reward Healthy Employees
11. Seattle Physician Shares Health IT Story in the Nation’s Capital
Post Your Comments:
(Date:10/13/2015)... , ... October 13, 2015 , ... ... companies in the United States, today announced the release of its limited edition ... new Cranberry Cocktail Agua Fresca. All feature the unique flavor combinations and delicious ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... announced today their sponsorship of the Microsoft Dynamics AXUG, GPUG and NAVUG Summits ... GPUG Summit and NAVUG Summit are independent user conferences designed and led by ...
(Date:10/13/2015)... ... October 13, 2015 , ... Dr. Poneh Ghasri, dentist ... on September 18, 2015. The research, which was conducted at the Dental Institute at ... colleagues, show connections between stress during pregnancy and future dental health in the child. ...
(Date:10/13/2015)... ... ... Protein is essential to good health. You need it to make the bricks ... does the average man need in order to stay healthy? , The answer ... Harvard Men's Health Watch . Most Americans get about 15% of their calories ...
(Date:10/13/2015)... ... October 13, 2015 , ... Georgia Partnership ... in communities throughout Georgia, along with affiliate organizations, Alabama Partnership for Telehalth (ATP) ... telehealth summits for Fall 2015. , Each of the three conferences share ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... DIEGO , October 13, 2015 ... today announced the appointment of Harry Lander , PhD ... the Company,s Chairman & CEO David Koos as ... small molecule and immuno-oncological therapeutics. --> Regen ... the appointment of Harry Lander , PhD as its ...
(Date:10/13/2015)...  Yesterday Congresswoman Renee Ellmers (R-NC-02) visited ... located in Holly Springs, NC . ... ® (Influenza Vaccine) using cell-culture technology, a state-of-the-art production ... is not reliant on chicken eggs. 1,2 On ... business of Novartis AG in the US, which for ...
(Date:10/12/2015)... 12, 2015 Given the intricacy of ... challenging to deliver an ophthalmic drug effectively to a specific ... successful ocular drug delivery. These include dilution of a drug ... of conjunctiva and drug permeation issues with respect to the ... topical eye drops, is lost due to the aforementioned barriers. ...
Breaking Medicine Technology: