Navigation Links
Doctors and rheumatoid arthritis patients differ on perception of disease activity
Date:7/17/2012

Researchers from Austria have determined that patients with rheumatoid arthritis (RA) and their doctors differ on perception of RA disease activity. The study now available in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR) and published by Wiley, reports that RA patients cite joint pain as the reason for their perception of a change in their disease activity. Rheumatologists, however, stressed joint swelling as the major determinant for their perception of change in RA disease activity.

RA is a systemic rheumatic disease that causes inflammation, pain, tenderness and swelling of the joints, which may limit functional activities and lead to permanent disability. This chronic condition is prevalent in up to 1% of the population worldwide, often striking women between 20 and 40 years of age and those in developed countries according to the World Health Organization (WHO). In the U.S., the ACR reports more than one million adults are affected by RA.

Treatment goals for RA aim to interfere with the inflammatory process and early intervention is recommended by experts. Moreover, the ACR and European League Against Rheumatism (EULAR) recently standardized criteria for measuring disease activity in RA, which were published in Arthritis Care & Research and includes:

  • Clinical Disease Activity Index (CDAI)
  • Disease Activity Score with 28-joint counts (erythrocyte sedimentation rate or C-reactive protein) (DAS-28)
  • Patient Activity Scale (PAS)
  • PAS-II
  • Routine Assessment of Patient Index Data with 3 measures (RAPID 3)
  • Simplified Disease Activity Index (SDAI)

"Discussion of treatment options by patients and physicians is important in the management of RA," explains lead author Dr. Daniel Aletaha with Medical University Vienna in Austria. "Many times there is a discrepancy between patients' and doctors' views of disease activity, with doctors providing a better rating than the patients." Currently patients may be asked to assess their disease using the patient global assessment (PGA) and rheumatologists typically measure RA disease with the evaluator global assessment (EGA).

Researchers identified 646 RA patients, who began treatment with methotrexate, from an observational patient database. Patients and physicians completed the PGA and EGA assessments, respectively, which the team used to analyze their determinants.

Results indicate that 78% of PGA variability and 67% of EGA variability could be explained by different measures in the RA patients: PGA variation is determined to about 76% by pain, 1.3% by function, and 0.5% by swollen joints. EGA variations were attributed to: 61% by swollen joints, 5% by pain, 0.6% by function, 0.4% by C-reactive protein, and 0.3% by tender joints.

Dr. Aletaha concludes, "Our study shows pain really drives patient perception of disease activity, while physicians mostly rely on the number of swollen joints when they interpret a patient's disease activity. The discrepancy of perception between patient and physician were calculated as PGA minus EGA. Pain levels and joint swelling are again explaining these discrepancies to a great deal." The authors suggest that further understanding of the reasons behind the differing views of disease activity could lead to improved shared decision making between patients and physicians in managing RA.


'/>"/>
Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Related medicine news :

1. Study finds doctors have exaggerated fears when starting patients on insulin
2. Doctors Detail High Costs of Fighting Malpractice Claims
3. Callahan honored for improving older adults health in their doctors offices
4. Doctors Urge Routine Skin Screenings
5. Doctors Restore Some Hand Function to Quadriplegic Patient
6. Men Can Still Ask for PSA Test, and Some Should, Doctors Say
7. Female Doctors Earn Less Than Male Counterparts: Study
8. Male doctors make $12K more per year than female doctors
9. Is it constitutional for states to regulate pharmaceutical gifts and meals to doctors?
10. Doctors cite concern for patients, colleagues top motives for working sick
11. Hospitals communication during residency matching may put stress on OB-GYN doctors-in-training
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2016)... ... December 10, 2016 , ... ... Santa are all sources of external stimuli that can put a great deal ... pressure to spread holiday cheer through gifts, food and festive gatherings can lead ...
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... ... counseling and aural rehabilitation—provided by audiologists—to remain a critical part of public access ... and Drug Administration (FDA) announced this week that, starting immediately, it ...
(Date:12/9/2016)... ... , ... The Justin Veatch Fund announced Thursday that The ... Whispering Spirits and its discussion guide for use by all of its ... the war against teen drug abuse. NCADD is the oldest anti-addiction advocacy organization ...
(Date:12/9/2016)... ... December 09, 2016 , ... MEDI+SIGN®, a provider ... that a new solution for Emergency Departments (ED) has been added to their ... Emergency Department examination rooms, and with a simplified pallet of information available to ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... ... Compensation Research Institute (WCRI) officially opened registration today for its 33rd Annual ... in Boston, MA . , The theme of the conference is “Persistent Challenges ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... de 2016  A Mederi Therapeutics Inc . anunciou aprovação regulatória, pela ... para a doença do refluxo gastroesofágico (DRGE). Foto -  http://photos.prnewswire.com/prnh/20161207/446903 ... ... Live Stretta procedure performed and broadcast during the Chinese Congress of ... , , ...
(Date:12/8/2016)... Pa. , Dec. 8, 2016  Pennsylvania ... Secretary of Drug and Alcohol Programs Gary ... and insomnia medications, known as benzodiazepines, developed with ... "Benzodiazepines are medications that are frequently prescribed ... when they are used with opioid pain medications, ...
(Date:12/8/2016)... 2016 True Health Diagnostics today announced ... services and management expertise to hospital systems throughout ... more doctors and patients to benefit from state-of-the-art ... Logo - http://photos.prnewswire.com/prnh/20161208/447162LOGO ... pressure to contain costs, have struggled to keep ...
Breaking Medicine Technology: