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Doctors See Return of Kaposi's Sarcoma in Handful of AIDS Patients
Date:9/26/2007

The skin cancer, which causes lesions, can be controlled with newer treatments

WEDNESDAY, Sept. 26 (HealthDay News) -- San Francisco doctors say they've seen a small number of longtime HIV patients with mild cases of Kaposi's sarcoma, a potentially dangerous condition that once plagued people with AIDS.

It's not clear why Kaposi's sarcoma is making a comeback, or whether it may pose a significant health threat to AIDS patients. Still, it's unusual that the condition is appearing in people who have largely controlled the AIDS virus in their bodies, said report lead author Dr. Toby Maurer, associate professor of dermatology at the University of California, San Francisco.

Kaposi's sarcoma, a type of skin cancer that causes disfiguring lesions, was largely limited to Mediterranean men before the AIDS epidemic. When the epidemic began in the United States, many gay men with AIDS developed the condition, apparently because their bodies already harbored the virus that causes it, Maurer said.

Kaposi's sarcoma stigmatized AIDS patients by causing lesions on their faces, and some people died. But a new generation of AIDS drugs released in the late 1990s helped patients strengthen their immune systems and kept Kaposi's sarcoma at bay, at least in the Western world.

The condition remains common in Africa, where it affects both men and women, Maurer said.

The condition hasn't disappeared entirely in the United States, however, and is still seen in AIDS patients who don't take antiretroviral drugs.

In a new report, published in a letter to the editor in the Sept. 27 issue of the New England Journal of Medicine, Maurer and his colleagues said they've seen an "unusual" cluster of nine cases of Kaposi's sarcoma in patients who have their HIV infection under control.

The patients, who were diagnosed with Kaposi's sarcoma between 2004 and 2006, had been HIV-positive for an average of
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