Navigation Links
Doctors' Guide to Cancer Drugs May Need Revising
Date:2/17/2009

Physicians often rely on outdated data when making 'off-label' decisions, study says

MONDAY, Feb. 16 (HealthDay News) -- Doctors may not always have complete or clear information when they prescribe cancer medications for uses beyond what the drugs have been approved for, a new study finds.

According to the report, published in the Feb. 17 online issue of Annals of Internal Medicine, the online and hard-copy resource used by oncologists and pharmacists, known as the compendia, does not always contain clear or updated information on using medications for "off-label" purposes, such as treating diseases other than those approved by the U.S. Food and Drug Administration.

Doctors and pharmacists often rely on the compendia for off-label dosage information, making it an authoritative source, in some instances, when a question arises about whether insurance will cover a drug for off-label use.

But the researchers found a lack of systematic methods to ensure the compendia information is regularly reviewed or updated.

"Oncologists and pharmacists use the compendia to guide choice of drugs for cancer patients that are not FDA-approved for use in that patient's disease -- an example would be bevacizumab, or Avastin, for brain cancer," the study's lead investigator, Dr. Amy Abernethy, an oncologist at Duke University, said in a news release issued by the school. "Bevacizumab is approved for use in diseases such as colorectal and lung cancer; it is not FDA-approved for brain tumors. But we have evidence that suggests it could be effective in this population, including peer-reviewed studies."

Abernethy's team, from the Duke Comprehensive Cancer Center, also found inconsistencies and confusion in how some commonly used compendia presented information and updated it. Some entries, for example, were more detailed than others, and information was presented in different ways for different drugs.

"Our study found that there are some limitations in the way the compendia are currently presented, and there are opportunities to improve the system," Abernethy said. "Determining how to improve it will be the next step for policymakers."

More information

The U.S. Food and Drug Administration has more about prescription drugs.



-- Kevin McKeever



SOURCE: Duke University, news release, Feb. 16, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Many Hospital Patients Cant ID Their Doctors
2. Wanted: Pioneer IVF Babies Bay Area Fertility Doctors Launch National Search for First IVF Babies Born 25 Years Ago
3. Doctors Fear Patients Not Filling Prescriptions
4. Unbelievable Lack Of Marketing Knowledge Forces Doctors To Quit Practice.
5. Doctors of Optometry Cheer Obamas Call to Action on Childrens Vision
6. Consumer Advocates Call on Legislature to Support Governors Ban on Pharmaceutical Gifts to Doctors
7. Study shows that primary care doctors miss opportunities to recommend colon cancer screening
8. Columbia Doctors, the Physicians and Surgeons of Columbia University Select MxSecure, Inc., as Their Medical Transcription Vendor of Choice
9. AOA Doctors of Optometry Partner With FDA and Other Industry Leaders to Develop New Measures to Better Protect Contact Lens Wearers
10. New Web Site Connects Patients with Experienced Doctors
11. Eye Doctors Offer Advice for Viewers on Super Bowl 3D Ads
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Doctors' Guide to Cancer Drugs May Need Revising
(Date:12/2/2016)... ... December 02, 2016 , ... Yisrayl Hawkins, at The House of Yahweh ... generation fits into Bible Prophecy. Yisrayl says this generation, known as the Last Generation, ... showing how the details line up exactly with Bible Prophecy – a protected way ...
(Date:12/2/2016)... ... December 02, 2016 , ... Clarify Health ... has raised $6.0 million in an initial round of funding. The round was ... and their caregivers can receive far better care through the application of the ...
(Date:12/2/2016)... ... December 02, 2016 , ... Today CloudMine, a secure, ... was named the best Sales Team of 2016 as part of the 2016 ... by the Software & Information Industry Association (SIIA), the principal trade association for ...
(Date:12/2/2016)... FL (PRWEB) , ... December 02, 2016 , ... ‘Tis ... are winners of $1,000 each from the National Family Partnership and the Drug Enforcement ... families who decorated their homes and the 10 winning schools who decorated their campuses ...
(Date:11/30/2016)... , ... November 30, 2016 , ... ... they now offer a comprehensive in-house dental plan for all patients. Understanding that ... a plan that gives patients a number of perks, including discounts on many ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2016 Orthopedic Implants (Including Spinal Implants, ... to Gain a Significant Market Share Owing to a Large ... ... According to a new report by Persistence ... Packaging: Clamshell Product Type Segment Projected to Witness a Significantly ...
(Date:12/2/2016)... MONMOUTH JUNCTION, N.J. , Dec. 2, 2016 /PRNewswire/ ... critical care immunotherapy leader commercializing its European Union approved ... in critically-ill and cardiac surgery patients worldwide, announced that ... present at the 9th Annual LD Micro Main ... 8 th , 2016 at the Luxe Sunset Boulevard ...
(Date:12/2/2016)... NEW YORK , December 2, 2016 ... at 5,251.11, down 1.36%; the Dow Jones Industrial Average edged ... closed at 2,191.08, down 0.35%. Losses were broad based as ... Today, Stock-Callers.com has initiated research reports on the following Services ... N.V. (NASDAQ: QGEN ), INC Research Holdings Inc. ...
Breaking Medicine Technology: