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Docs Claim Transplant Cured Man of HIV, But Experts Urge Caution
Date:12/15/2010

d with HIV in the future? Yes," she said.

This treatment also carries with it a 30 percent risk of death, Fischl added.

"That he was young and got through it is quite remarkable," she said. "I would never give this to a healthy patient. I could never justify it. If you use this therapy, 30 percent of your patients could die from the intervention."

Fischl said the study does present new ways to look for an HIV cure, however. "This is leading to looking at gene therapy in a totally different way," she said.

"We tell our patients that this was a very particular situation. What made this work was that he got a very rare donor. It opens doors for us, but we are years away from potentially making gene therapy more broadly available," Fischl said. "It shows us the hurdles we have to get over to get to the cure."

Rowena Johnston, director of research at the Foundation for AIDS Research, also added a note of caution but said that the case "speaks to the promise of research."

"We need to be clear that what was done for this patient was not something that can be done on a wide scale," Johnston said. "It really was a lucky case for this one guy that all the stars aligned and that all of the factors that needed to come together really did."

However, gene therapy might be an avenue to pursue, Johnston said. "We're a long way from that. There's a lot of technology that needs to be perfected, there's a lot of issues that need to be considered in terms of how you would deliver this to patients in a safe way and how the long-term effectiveness of that treatment might pan out," she said.

But the man's example has given gene therapy a "shot in the arm," Johnston said. "It's not just a pipe dream any more, somebody has been cured and we need to work out how we can come up with a cure that will be more readily available to everybody out there who needs it. That's over 30 million people living with HIV."

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Docs Claim Transplant Cured Man of HIV, But Experts Urge Caution
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