Navigation Links
Do women fare worse with some heart devices?
Date:11/5/2007

PHILADELPHIA While ICDsimplantable cardioverter defibrillatorsare the device of choice to manage abnormal heart rhythms, a new study led by cardiologists at the University of Pennsylvania School of Medicine suggests that women with ICDs fare less well than their male counterparts.

In a retrospective analysis to be presented at the AHA Scientific Sessions 2007 on Sunday, November 4 (Poster #C148; 3 p.m.), lead researcher Andrea Russo, M.D., Clinical Associate Professor of Medicine, suggests that despite the proven overall effectiveness of the devices, women had a greater risk of dying than men.

Using data from the completed INTRINSIC RV trial, the researchers compared results from 1237 men and 293 women. (The INTRINSIC RV trial, which was completed in 2006, compared dual- and single-chamber ICDs.)

There is a paucity of data comparing outcome and arrhythmic events in men vs. women with ICDs, said Dr. Russo, who is also Director of the Electrophysiology Laboratory at Penn Presbyterian Medical Center. We chose the INTRINSIC RV study because it enrolled the largest total number of women.

The researchers found that women with ICDs required hospitalization and had a higher mortality than men with the device. However, after adjusting for other factors, such as the presence of coronary artery disease, heart failure and medical treatment, these gender differences in outcome were no longer present.

According to Dr. Russo, this means that women may be sicker by the time they receive ICDs. In addition, women appear to be under-treated with medications such as beta-blockers and ACE inhibitors in this study. On the other hand, she notes, women appeared to be just as likely as men to receive appropriate shocks from their devices for abnormal rapid rhythms from the lower chamber of the heart.

This research confirms the need for additional studies to learn why there is such a disparity between the sexes, Dr. Russo says. Then we also can learn which women will most benefit from the devices.

In conclusion, the researchers postulate that the differences may be related to how aging and lifestyle factors affect women and men who receive ICDs. They recommend that additional research focus on gender differences among patients who receive implantable cardioverter defibrillators.


'/>"/>

Contact: Nan Myers
nan.myers@uphs.upenn.edu
215-662-2560
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
2. Work-Family Conflict Dogs Air Force Women After Deployment
3. Work-Family Conflict Dogs Air Force Women After Deployment
4. Antioxidant Supplements May Raise Womens Skin Cancer Risk
5. Early Weight Loss in Women Linked to Dementia
6. For Health Info, Women Often Turn to the Web
7. Smoking increases risks for head and neck cancers for men and women
8. New Study Reports High Injury Rates for Hotel Workers, Even Higher Rates for Women and Nonwhites
9. Passive smoking increases sleep disturbance among pregnant women
10. Trial to Test Gene Therapy for Angina in Women
11. Exercise and yoga improves quality of life in women with early-stage breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... ambulance transport experience for the millions of people who require these medical transport ... taxi industry through the use of technology. Now, SmartEMS has put forth an ...
(Date:6/26/2016)... ... , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... a whole new perspective by using the title layers in ProSlice Levels to ... ProSlice Levels contains over 30 Different presets to choose from. FCPX users ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from ... at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center ... care topics including advance care planning, healthcare costs and patient and family engagement. ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening to conquer ... in advanced audiology and hearing aid technology, has today ... world,s first internet connected hearing aid that opens up ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... , TwinLink™ - the first dual communication ...
Breaking Medicine Technology: