Navigation Links
Do elite 'power sport' athletes have a genetic advantage?
Date:9/25/2013

Philadelphia, Pa. (September 25, 2013) - A specific gene variant is more frequent among elite athletes in power sports, reports a study in the October issue of The Journal of Strength and Conditioning Research, official research journal of the National Strength and Conditioning Association (NSCA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

A "functional polymorphism" of the angiotensiogen (AGT) gene is two to three times more common in elite power athletes, compared to nonathletes or even elite endurance athletes, according to the new research by Paweł Cięszczyk, PhD, of University of Szczecin, Poland, and colleagues. They write, "[T]he M23T variant in the AGT may be one of the genetic markers to investigate when an assessment of predisposition to power sports is made."

Gene Variant More Common in Elite Power Athletes

The researchers analyzed DNA samples from two groups of elite Polish athletes: 100 power-oriented athletes, from sports such as power-lifting, short-distance runners, and jumpers; and 123 endurance athletes, such as long-distance runners and swimmers and rowers. All athletes competed at the international leveleg, World and European Championships, World Cups, or Olympic Games. A group of 344 nonathletes were studied for comparison.

The analysis focused on the genotype of the M235T polymorphism of the gene AGT. "Polymorphisms" are genes that can appear in two different forms (alleles). A previous study found that the "C" allele of the AGT gene (as opposed to the "T" allele) was more frequent among elite athletes in power sports.

The genetic tests found that elite power athletes were more likely to have two copies of the C allelein other words, they inherited the C allele from both parents. This "CC" genotype was found 40 percent of the power athletes, compared to 13 percent of endurance athletes and 18 percent of nonathletes.

Power athletes were three times more likely to have the CC genotype compared to endurance athletes, and twice as likely compared to nonathletes. At least one copy of the C allele was present in 55.5 percent of power athletes, compared to about 40 percent of endurance athletes and nonathletes.

But Functional Significance Not Yet Clear

In a further analysis, the researchers found no differences in genotype between "top-elite" athletes who had won medals in international-level competition, compared to elite-level athletes who were not medalists.

The new study is the first to replicate previous, independent research showing an increased rate of the CC genotype of the AGT gene among power athletes on Spanish national teams. That study also found about a 40 percent prevalence of the CC genotype among elite power athletes.

The AGT gene is part of the renin-angiotensin system, which plays essential roles in regulating blood pressure, body salt, and fluid balance. There are several possible ways in which the CC genotype might predispose to improved power and strength capacityincluding increased production of angiotensin II, which is crucial for muscle performance. However, the researchers emphasize that the "functional consequences" of the M235T polymorphism remain to be determined.

The study contributes to the rapidly evolving body of research on genetic factors related to exercise, fitness, and performancewhich may one day have implications for identification and training of potential elite-level athletes. Dr Cięszczyk and coauthors conclude, "Identifying genetic characteristics related to athletic excellence or individual predisposition to types of sports with different demands (power or endurance oriented) or even sport specialty may be decisive in recognizing athletic talent and probably will allow for greater specificity in steering of sports training programs."


'/>"/>

Contact: Connie Hughes
connie.hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health
Source:Eurekalert

Related medicine news :

1. Rush joins elite group of institutions with accredited research programs
2. U.S.A. Hurdle Specialist Kellie Wells has Joined Elite Athletes Tiger Woods, Hines Ward and Takaishi Saito in Using Cell Therapy
3. Cenegenics Atlanta Moves to Premier Location, Joining Elite Tenant Roster List
4. Boston Medical Center awarded elite distinction as a 2012 Leapfrog Top Hospital
5. Hearing Aids Elite Announces Launch of New Blog
6. QuickMedical Announces QM-Elite Nitrile Gloves Available In New 200/Box Money Saving Package
7. Pathways Home Health & Hospice Receives 2012 HomeCare Elite Top Honor for Quality Care
8. Britax Roundabout 55 Gets High Marks from EliteCarSeats.com
9. QuickMedical Introduces New QM-Elite Non-Woven Disposable Face Masks, Shoe Covers, Bouffants and Medical Shorts
10. Ecommerce Software Provider, Shopping Cart Elite Launches Visitor Generated SEO Plugin
11. “We Are Not Worried”, Says Shopping Cart Provider, Shopping Cart Elite in Response to Latest Google Webmaster Guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ITASCA, Ill. , June 23, 2016  In a startling ... states are failing their residents by lacking a comprehensive, proven plan ... , a definitive ranking of how states are tackling the ... rating to only four states – Kentucky , ... and Vermont . Of the 28 failing states, ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Key Pharma News Issue 52" report to their offering. ... need in influenza treatment creates a favourable commercial environment for ... and growing patient base that will serve to drive considerable ... flu vaccine would serve to cap sales considerably, but development ...
(Date:6/23/2016)... today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in Bogota. ... ... ... ... Astellas is a ...
Breaking Medicine Technology: