Navigation Links
Disruption of biological clocks causes neurodegeneration, early death
Date:1/10/2012

that disrupts circadian rhythms and another that causes flies to develop brain pathologies during aging. These double mutants had a 32-50 percent shorter lifespan, lost much of their motor function, and developed significant "vacuoles" or holes in their brains far sooner than flies with a functional clock.

The decline and loss of clock function may be just the beginning of a damaging, circular process, said Jadwiga Giebultowicz, an OSU professor of zoology, member of the OSU Center for Healthy Aging Research and project leader.

"When the biological clock begins to fail, rhythms that regulate cell function and health get disrupted, and we now know that this predisposes the brain to neurodegeneration," Giebultowicz said. "But that neurodegeneration, in turn, may cause more damage to the clock function.

"A healthy biological clock helps protect against this damage," she said. "When the clock fails, the damage processes speed up."

Aging is closely associated with this process, Giebultowicz said, but it's not clear exactly how. Molecular clock oscillations decline during aging. Finding ways to restore them might form a possible therapy for biological clock damage and help to prevent disease, and work in that area will be part of future research.


'/>"/>

Contact: Jadwiga Giebultowicz
giebultj@science.oregonstate.edu
541-737-5530
Oregon State University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers observe disruptions of daily rhythms in Alzheimers patients brains
2. Disruption of nerve cell supply chain may contribute to Parkinsons
3. Debt ceiling agreement essential to prevent disruption of care for Medicare & Medicaid patients
4. Penn team links schizophrenia genetics to disruption in how brain processes sound
5. Study carried out into biological risks of eating reptiles
6. Biological clock could be a key to better health, longer life
7. New method to grow arteries could lead to biological bypass for heart disease
8. U of T researchers crack splicing code, solve a mystery underlying biological complexity
9. Adolescent brains biologically wired to engage in risky behavior, study finds
10. Length of biological marker associated with risk of cancer
11. Ticking biological clock increases womens libido, new research shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... 28, 2015 , ... Approximately 2,000 United Methodists are expected ... helping children, a thank you to the many creative and generous ways in ... United Methodist initiative to end malaria deaths. , The Columbus Zoo and Aquarium ...
(Date:8/28/2015)... ... 2015 , ... An article published August 19th by the LA ... through to open a pizzeria in Westchester. Mr. LaRocco was aware from opening prior ... but the current process, having already gone on for over a year, is taking ...
(Date:8/28/2015)... TX (PRWEB) , ... August 28, 2015 , ... For ... Center is taking part with their subsidiary USPI Tenet Health. , The American Heart ... fight heart disease and stroke. They believe that together, a difference can be made. ...
(Date:8/28/2015)... ... August 28, 2015 , ... As reported by Medical Daily ... FDA clearance for results that last for two years, the longest of any cellulite ... who are looking for a long-lasting, effective solution for their cellulite, according to Dr. ...
(Date:8/28/2015)... Michigan (PRWEB) , ... August 28, 2015 , ... On ... Western Michigan, joined as sponsor of the “Music With A Mission” benefit concert in ... behind the event was to raise money to support music education programs in the ...
Breaking Medicine News(10 mins):Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2
... the second year in a row, the American Red Cross and ... their families around the world this holiday season. This year a ... 300 military installations and hospitals around the world. , ... , There are many ways you can ...
... 2007, - ... - Debt financing is ... VANCOUVER, Nov. 26 /PRNewswire-FirstCall/ - CRH Medical Corporation (CRM:TSX-V) announced today ... and unveiled a new strategy designed to mitigate the need to obtain ...
... Streamline Health Solutions, Inc. (Nasdaq: STRM ) ... E. Vick, Jr., as the Company,s interim Chief Financial Officer ... Officer. Mr. Vick may be considered as a candidate ... Chief Financial Officer, Mr. Vick will also continue to serve ...
... Watson Pharmaceuticals,Inc. (NYSE: WPI ... announced,that its subsidiary, Watson Laboratories, Inc., has ... Food and Drug Administration on its Abbreviated,New ... (XL) in the 150 mg strength. ...
... may be affected by phthalates in these products, experts ... exposed to a common hairspray chemical while at work ... an abnormally placed urinary opening, a new report says. ... nail and hair products contain chemicals called phthalates, such ...
... WASHINGTON, Nov. 26 Talk about being a Grinch! On ... of the government workforce -- are having their benefits cut ... , That,s right, BCBS has drastically altered a ... upon for their healthcare coverage -- and hasn,t bothered to ...
Cached Medicine News:Health News:Remember to Send 'Holiday Mail For Heroes' and Thank a Service Member this Thanksgiving 2Health News:CRH Medical reports Q3 2008 results 2Health News:CRH Medical reports Q3 2008 results 3Health News:CRH Medical reports Q3 2008 results 4Health News:CRH Medical reports Q3 2008 results 5Health News:CRH Medical reports Q3 2008 results 6Health News:Streamline Health Announces Appointment of Interim Chief Financial Officer 2Health News:Watson Pharmaceuticals Receives FDA Final Approval for Generic Wellbutrin XL(R) 150 mg 2Health News:Blue Cross/Blue Shield Christmas Gift to Federal Employees: Surprise, We're Cutting Your Benefits!; Patients, Doctors and Health Care Providers Outraged 2
(Date:8/28/2015)... The scientific team of a new biotech company ... academics in the field of aging Prof. Robert J. ... for model animals - 10 fold for nematodes) has recently ... primarily, around the stability and stress resistance of certain gene ... analysis of a model gene network links aging, stress resistance, ...
(Date:8/28/2015)... LOS ANGELES , FARUM, Denmark ... -- On July 31, 2015 the US Food ... for the treatment of Major Depressive Disorder in adult patients ... medication in the current episode. TMS is a non-invasive technique ... implicated in patients suffering from Major Depressive Disorder. The procedure ...
(Date:8/28/2015)... y LONDRES, 28 de agosto de ... PHIA) anunció hoy su participación en el  Congreso ... sus soluciones cardiológicas más recientes y novedosas, entre ... que conectan a las personas y la tecnología ... ayudar a diagnosticar, guiar los tratamientos y permitir ...
Breaking Medicine Technology:Gero: Physics Meets Biology to Help Defeat Aging 2Gero: Physics Meets Biology to Help Defeat Aging 3Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 2Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5
... 29, 2011 UBM Canon,s leading brand, Japan Medical Design ... the launch of its new Japanese-language website with enhanced content and ... website allows users to find the resources and information they ... Editor-in-Chief, EMDT , JMDMT , and CMDM ...
... June 29, 2011 Cayenne Medical, Inc., a private ... II Meniscal Repair System, its second generation device for ... on display at the 2011 American Orthopaedic Society for ... CA.   Tal David, MD, orthopedic sports ...
Cached Medicine Technology:UBM Canon Announces New Japanese-Language Website for Japan Medical Design & Manufacturing Technology: www.jmdmt.com 2Cayenne Medical, Inc. Launches CrossFix® II Meniscal Repair System 2
... management software - was designed by ... improvement tool helps diabetes care providers ... bridges medicine with technology by providing ... information technology product. This diabetes ...
... management of diabetes in order to maintain tight ... effective way to reduce or even prevent diabetes-related ... improving a diabetes patients quality of life, however, ... have been the guiding factors in the development ...
... by the CGMS System Gold can assist ... program based on detailed glycemic profiles. Its ... improve motivation and collaboration with patients.1, ... with all diabetes patients, it may be ...
... Biographer is intended for detecting trends and ... (aged 18 and older) and children/adolescents (aged ... supervise the use of the G2 Biographer ... intended to supplement, not replace, conventional blood ...
Medicine Products: