Navigation Links
Disparities among patients with extremity soft-tissue sarcomas
Date:1/21/2008

A new study reveals significant racial and ethnic differences in the treatment and survival of patients with soft-tissue sarcomas, a rare but dangerous cancer that begins in muscle, fat, blood vessels or other supporting tissue of the body. The findings are published in the March 1, 2008, issue of CANCER, a peer-reviewed journal of the American Cancer Society.

While racial and ethnic disparities in treatment and disease outcomes have been reported for various cancers, this is the first study to address disparities in extremity soft-tissue sarcomas. Extremity soft-tissue sarcomas affect approximately 9,220 patients in the United States, more than half of which are estimated to involve an upper or lower extremity.

Preserving limbs with surgery is the accepted standard treatment for adult extremity soft tissue sarcomas. Amputation is seldom necessary because radiation therapy, given either before or after surgery, can effectively preserve limbs in up to 91 percent of cases. However, the research showed that this doesnt always happen for all patients.

Utilizing a database of the National Cancer Institute, Dr. Steve R. Martinez, a surgical oncologist with UC Davis Cancer Center and lead author of the study, and Dr. Anthony S. Robbins of the California Cancer Registry, mined the Surveillance, Epidemiology and End Results (SEER)-Medicare database and identified adult patients in the United States with extremity soft-tissue sarcomas who were diagnosed and treated between 1988 and 2003. Eligible patients included 4,636 whites, 663 blacks, 696 Hispanics and 411 Asians. Comparisons of treatments and survival were then made for each population.

The authors found that blacks had significantly lower rates of surgeries that would have saved their arm or leg, they had the highest rates of amputations, and they were the least likely to receive additional treatments that would lead to improved survival. The study found when compared with whites, blacks had a 39 percent higher death rate related to their disease, even when taking into account various factors known to influence sarcoma-specific survival.

In their analysis, the researchers also found that Hispanics tended to be diagnosed with extremity soft-tissue sarcomas at a younger age than whites, blacks, and Asians; blacks, Hispanics, and Asians tended to have larger tumors than whites; Asians were most likely to undergo limb-sparing procedures, and had the lowest rates of amputation; and Hispanics had lower rates of limb preservation and higher rates of amputation when compared with whites.

Martinez said that the study does not address the reasons for the different outcomes for patients with the same disease, but added that his study should be a wake-up call for physicians treating soft-tissue sarcomas.

We need to take a close look at the factors that lead to worse results for one population when compared to others, he said. And we need to focus our efforts toward improving extremity soft-tissue sarcoma treatment and outcomes for all patients, especially for those most at risk.


'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. San Francisco City Hall Turns Pink, Draws Attention to Disparities in Breast Cancer Screening, Treatment
2. LSU Forum Examines Health-Care Disparities and Access to Care
3. Despite efforts, significant racial disparities in cancer therapy still exist
4. Racial disparities persist in cancer care
5. It takes a community to address cancer disparities among underserved minority populations
6. New perspectives on health disparities in breast cancer research
7. Genetic and behavioral differences add to prostate cancer disparities
8. Genetic differences point to ethnic and racial disparities in colorectal cancer risk
9. Kaiser Permanente Recognized by NCQA for Innovative Program to Reduce Health Care Disparities
10. New study questions disparities in vascular surgery among Hispanics
11. Studies Show Importance of Language Services on Reducing Disparities, Increasing Quality of Patient Care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Dublin ... addition of the " Global Markets for Spectroscopy ... This report focuses on the ... review, including its applications in various applications. The report ... includes three main industries: pharmaceutical and biotechnology, food and ...
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced ... as its e-clinical software solution of choice.  This ... best possible value to their clients by offering ... The preferred relationship establishes nowEDC as the EDC ... for MedSource,s full-service clients.  "nowEDC has long been ...
Breaking Medicine Technology: